Congo Tak‐Shing Ching
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View article: Thermal Cycling Stimulation via Nasal Inhalation Attenuates Aβ25–35-Induced Cognitive Deficits in C57BL/6 Mice
Thermal Cycling Stimulation via Nasal Inhalation Attenuates Aβ25–35-Induced Cognitive Deficits in C57BL/6 Mice Open
Alzheimer’s disease (AD) remains a significant public health challenge, with current treatments limited partly due to the difficulty of delivering therapeutics across the blood–brain barrier (BBB). The nose-to-brain (N-2-B) pathway offers …
View article: Bioengineering an AI-augmented platform for remote mental health interventions
Bioengineering an AI-augmented platform for remote mental health interventions Open
This study developed and tested a new teletherapy system that uses artificial intelligence (AI) to improve remote psychological treatment and reduce therapists’ workload. The system includes a case management platform and a video-based the…
View article: Noncontact monitoring of the peripheral microcirculation using laser speckle contrast imaging to evaluate the skin perfusion pressure
Noncontact monitoring of the peripheral microcirculation using laser speckle contrast imaging to evaluate the skin perfusion pressure Open
[[abstract]]The skin perfusion pressure (SPP) is traditionally measured with laser Doppler flowmetry (LDF), but this technique is limited by its single-point fiber optic probe, the need to contact the skin, and susceptibility to various fa…
View article: Thermal cycling-stimulation via nasal inhalation attenuates Aβ<sub>25-35</sub>-induced cognitive deficits in C57BL/6 mice
Thermal cycling-stimulation via nasal inhalation attenuates Aβ<sub>25-35</sub>-induced cognitive deficits in C57BL/6 mice Open
Alzheimer’s disease (AD) continues to pose a significant public health challenge, with current treatments demonstrating limited effectiveness, partly due to the difficulty of delivering therapeutics across the blood-brain barrier (BBB). Th…
View article: An Innovative Real-Time Cell Viability Analysis: A Cutting-Edge Flexible Bioimpedance Sensor
An Innovative Real-Time Cell Viability Analysis: A Cutting-Edge Flexible Bioimpedance Sensor Open
There are many compounds used to treat cancer, but still, only 20% of proposed anticancer agents have been commercialized after clinical trials due to serious side effects and unsatisfactory results. To screen potential drugs precisely and…
View article: Enhancing Diagnostic Accuracy for Knee Osteoarthritis Using a Deep Learning Approach
Enhancing Diagnostic Accuracy for Knee Osteoarthritis Using a Deep Learning Approach Open
This research introduces a deep learning framework that combines convolutional neural networks with autoencoders to improve the diagnostic accuracy of knee osteoarthritis. The study utilized a publicly available dataset from the Mendeley D…
View article: Cole Parameter Estimation for Calibrating the Electrical Impedance Tomography System
Cole Parameter Estimation for Calibrating the Electrical Impedance Tomography System Open
Impedance measurement inaccuracies and difficulties in modeling the complex electrical properties of biological tissues often compromise the diagnostic reliability of Electrical Impedance Tomography (EIT). To address these limitations, thi…
View article: IoT‐Based Hand Hygiene Compliance Monitoring System and Validation of Its Effectiveness in Hospital Environments (Global Challenges 12/2024)
IoT‐Based Hand Hygiene Compliance Monitoring System and Validation of Its Effectiveness in Hospital Environments (Global Challenges 12/2024) Open
The cover image is based on the Article IoT‐Based Hand Hygiene Compliance Monitoring System and Validation of Its Effectiveness in Hospital Environments by Ju‐Yu Wu et al., https://doi.org/10.1002/gch2.202400124. [Image: see text]
View article: Validation of Ultrasound Measurement of Vastus Lateralis for Appendicular Skeletal Muscle Mass in Chronic Kidney Disease Patients with Hemodialysis
Validation of Ultrasound Measurement of Vastus Lateralis for Appendicular Skeletal Muscle Mass in Chronic Kidney Disease Patients with Hemodialysis Open
Background: Chronic kidney disease patients undergoing hemodialysis (HD) are at a high risk of developing sarcopenia. This study aimed to validate the performance of ultrasound (US) measurements of the vastus lateralis (VL) for estimating …
View article: IoT‐Based Hand Hygiene Compliance Monitoring System and Validation of Its Effectiveness in Hospital Environments
IoT‐Based Hand Hygiene Compliance Monitoring System and Validation of Its Effectiveness in Hospital Environments Open
Healthcare‐associated infection (HAI) is the most common adverse medical event that affects patients. Internationally, healthcare workers (HCWs) are monitored for hand hygiene compliance to reduce HAI risk. While direct observation is cons…
View article: Improving the early diagnosis and clinical outcomes of shock patients via laser speckle contrast imaging assessment of peripheral hemodynamics
Improving the early diagnosis and clinical outcomes of shock patients via laser speckle contrast imaging assessment of peripheral hemodynamics Open
Shock is defined as a critical circulatory failure that requires prompt diagnosis to optimize patient outcomes. Traditional diagnostic methods have limitations, including contact-based measurements, high costs, and lengthy procedures. The …
View article: Design and Implementation of a Cost‐Effective, Portable Impedance Analyzer Device with <scp>AD5941</scp>
Design and Implementation of a Cost‐Effective, Portable Impedance Analyzer Device with <span>AD5941</span> Open
This study proposes a cost‐effective, small‐size, and portable impedance analyzer using the AD5941 Analog Front End (AFE) that makes frequency sweep measurement for various applications. The design utilizes a microcontroller and an AD5941 …
View article: A Comparative Study of Machine Learning Classifiers for Enhancing Knee Osteoarthritis Diagnosis
A Comparative Study of Machine Learning Classifiers for Enhancing Knee Osteoarthritis Diagnosis Open
Knee osteoarthritis (KOA) is a leading cause of disability, particularly affecting older adults due to the deterioration of articular cartilage within the knee joint. This condition is characterized by pain, stiffness, and impaired movemen…
View article: Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system Open
Wound monitoring is crucial for effective healing, as nonhealing wounds can lead to tissue ulceration and necrosis. Evaluating wound recovery involves observing changes in angiogenesis. Laser speckle contrast imaging (LSCI) is vital for wo…
View article: Wave-Weighted Modulation in Electrical Impedance Tomography
Wave-Weighted Modulation in Electrical Impedance Tomography Open
This study proposes a wave-weighted modulation method to improve the distinction between areas with small conductivity differences in Electrical Impedance Tomography. The modulated signal is generated by modulating the probe and carrier si…
View article: Machine learning-enhanced gesture recognition through impedance signal analysis
Machine learning-enhanced gesture recognition through impedance signal analysis Open
Gesture recognition is a crucial aspect in the advancement of virtual reality, healthcare, and human-computer interaction, and requires innovative methodologies to meet the increasing demands for precision. This paper presents a novel appr…
View article: An Approximate Point-Spread Function for Electrical Impedance Tomography Imaging
An Approximate Point-Spread Function for Electrical Impedance Tomography Imaging Open
In Electrical Impedance Tomography, the ill-posed nature of the inverse problem and the interaction between the electric current and objects cause poor spatial resolution and blurring in the reconstructed images. This study proposes a nume…
View article: Comparative Analysis of Audio Processing Techniques on Doppler Radar Signature of Human Walking Motion Using CNN Models
Comparative Analysis of Audio Processing Techniques on Doppler Radar Signature of Human Walking Motion Using CNN Models Open
Artificial intelligence (AI) radar technology offers several advantages over other technologies, including low cost, privacy assurance, high accuracy, and environmental resilience. One challenge faced by AI radar technology is the high cos…
View article: IoT-based wearable health monitoring device and its validation for potential critical and emergency applications
IoT-based wearable health monitoring device and its validation for potential critical and emergency applications Open
The COVID-19 pandemic brought the world to a standstill, posing unprecedented challenges for healthcare systems worldwide. The overwhelming number of patients infected with the virus placed an enormous burden on healthcare providers, who s…
View article: Bioimpedance-Measurement-Based Non-Invasive Method for In Ovo Chicken Egg Sexing
Bioimpedance-Measurement-Based Non-Invasive Method for In Ovo Chicken Egg Sexing Open
Day-old male chick culling is one of the world’s most inhumane problems in the poultry industry. Every year, seven billion male chicks are slaughtered in laying-hen hatcheries due to their higher feed exchange rate, lower management than f…
View article: Emerging Wearable Biosensor Technologies for Stress Monitoring and Their Real-World Applications
Emerging Wearable Biosensor Technologies for Stress Monitoring and Their Real-World Applications Open
Wearable devices are being developed faster and applied more widely. Wearables have been used to monitor movement-related physiological indices, including heartbeat, movement, and other exercise metrics, for health purposes. People are als…
View article: A New Biorecognition-Element-Free IDμE Sensor for the Identification and Quantification of E. coli
A New Biorecognition-Element-Free IDμE Sensor for the Identification and Quantification of E. coli Open
The label-free biosensor has emerged as an effective tool for the purpose of early detection of causative pathogens such as Escherichia coli as a preventive measure. In this study, a biorecognition-element-free interdigitated microelectrod…
View article: Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and <scp>SerpinB2</scp> downregulation
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and <span>SerpinB2</span> downregulation Open
Urological chronic pelvic pain syndrome (UCPPS) manifests as pelvic pain with frequent urination and has a 10% prevalence rate without effective therapy. Nanoceria (cerium oxide nanoparticles [CNPs]) were synthesized in this study to achie…
View article: Intelligent Fall-Risk Assessment Based on Gait Stability and Symmetry Among Older Adults Using Tri-Axial Accelerometry
Intelligent Fall-Risk Assessment Based on Gait Stability and Symmetry Among Older Adults Using Tri-Axial Accelerometry Open
This study aimed to use the k-nearest neighbor (kNN) algorithm, which combines gait stability and symmetry derived from a normalized cross-correlation ( NCC ) analysis of acceleration signals from the bilateral ankles of older adults, to a…
View article: A Pioneer Study on a Non-invasive Method for in Ovo Chicken Egg Sexing.
A Pioneer Study on a Non-invasive Method for in Ovo Chicken Egg Sexing. Open
Background: Day-old male chicks culling is one of the world most inhumane problems in the poultry industry. Every year, seven billions of male chicks are being killed in laying-hen hatcheries, due to their higher feed exchange rate, lower …
View article: Cytotoxicity of ZnO Paper against Cancer Cells
Cytotoxicity of ZnO Paper against Cancer Cells Open
Paper incorporated with ZnO nanostructures (called ZnO paper) is a flexible substrate material with applications in many areas including UV detectors and gas sensors.In this work, we tested the cytotoxicity of ZnO paper against cancer cell…
View article: Ultraviolet Light Exposure Effect on the Nanoscale Current-Voltage Characteristics of Bare and Silicate Nanoparticle Incorporated 3-aminopropyltrimethylsiloxane Films Deposited Using a Focus Ion Beam-Milled Atomic Force Microscopy Tip
Ultraviolet Light Exposure Effect on the Nanoscale Current-Voltage Characteristics of Bare and Silicate Nanoparticle Incorporated 3-aminopropyltrimethylsiloxane Films Deposited Using a Focus Ion Beam-Milled Atomic Force Microscopy Tip Open
Polysilicon wire (PSW) sensor with a sensing membrane of 3-aminopropyltrimethylsiloxan (γ-APTES) incorporated with polydimethylsiloxane (PDMS)-treated silica nanoparticles (NPs) (γ-APTES+NPs nanocomposite) deposited by a focus ion beam (FI…
View article: A Dynamic Joint Angle Measurement Device for an Active Hand Rehabilitation System
A Dynamic Joint Angle Measurement Device for an Active Hand Rehabilitation System Open
Traditional methods of measuring a joint angle are neither repeatable nor accurate and cannot instantly display, record, and upload the data onto a cloud drive. These mechanisms require development if they are to be used to evaluate rehabi…
View article: Quantitative Ultrasound Texture Analysis to Assess the Spastic Muscles in Stroke Patients
Quantitative Ultrasound Texture Analysis to Assess the Spastic Muscles in Stroke Patients Open
This study aimed to investigate the feasibility of sonoelastography for determining echotexture in post-stroke patients. Moreover, the relationships of muscle echotexture features, muscle stiffness, and functional performance in spastic mu…