Kenneth L. Gage
YOU?
Author Swipe
Yersinia pestis Δ <i>ail</i> Mutants Are Not Susceptible to Human Complement Bactericidal Activity in the Flea Open
This work contributes to our understanding of how highly virulent Y. pestis evolved from its innocuous enteric predecessor. Among identified virulence factors is the attachment invasion locus protein, Ail, that is required to protect Y. pe…
Epidemiology, Ecology and Prevention of Plague in the West Nile Region of Uganda: The Value of Long-Term Field Studies Open
Plague, a fleaborne rodent-associated zoonosis, is a neglected disease with most recent cases reported from east and central Africa and Madagascar. Because of its low incidence and sporadic occurrence, most of our knowledge of plague ecolo…
The changing triad of plague in Uganda: invasive black rats<i>(Rattus rattus)</i>, indigenous small mammals, and their fleas Open
Rattus rattus was first reported from the West Nile Region of Uganda in 1961, an event that preceded the appearance of the first documented human plague outbreak in 1970. We investigated how invasive R. rattus and native small mammal popul…
Historical and genomic data reveal the influencing factors on global transmission velocity of plague during the Third Pandemic Open
Significance Plague is a devastating infectious disease that has caused three pandemics during the last millennia. Today, plague still causes sporadic cases every year and even some outbreaks. In this paper, we analyze how factors associat…
An Evaluation of Removal Trapping to Control Rodents Inside Homes in a Plague-Endemic Region of Rural Northwestern Uganda Open
Rodents pose a significant threat to human health, particularly in rural subsistence farming communities in Africa, where rodents threaten food security and serve as reservoirs of human pathogens, including the agents of plague, leptospiro…
View article: Drivers of flea (Siphonaptera) community structure in sympatric wild carnivores in northwestern Mexico
Drivers of flea (Siphonaptera) community structure in sympatric wild carnivores in northwestern Mexico Open
Host identity, habitat type, season, and interspecific interactions were investigated as determinants of the community structure of fleas on wild carnivores in northwestern Mexico. A total of 540 fleas belonging to seven species was collec…
Comparison of Zoonotic Bacterial Agents in Fleas Collected from Small Mammals or Host-Seeking Fleas from a Ugandan Region Where Plague Is Endemic Open
Fleas play critical roles in transmitting some infections among animals and from animals to humans. Detection of pathogens in fleas is important to determine human risks for flea-borne diseases and can help guide diagnosis and treatment. O…
Rat Fall Surveillance Coupled with Vector Control and Community Education as a Plague Prevention Strategy in the West Nile Region, Uganda Open
Plague, primarily a disease of rodents, is most frequently transmitted by fleas and causes potentially fatal infections in humans. In Uganda, plague is endemic to the West Nile region. Primary prevention for plague includes control of rode…
Small-Scale Die-Offs in Woodrats Support Long-Term Maintenance of Plague in the U.S. Southwest Open
Our longitudinal study of plague dynamics was conducted in north-central New Mexico to identify which species in the community were infected with plague, to determine the spatial and temporal patterns of the dynamics of plague epizootics, …
Ecological Traits Driving the Outbreaks and Emergence of Zoonotic Pathogens Open
Infectious diseases that are transmitted from wildlife hosts to humans, such as the Ebola virus and MERS virus, can be difficult to understand because the pathogens emerge from complex multifaceted ecological interactions. We use a wildlif…