Explanipedia

p63-negative thoracic NUT carcinoma - A potential diagnostic pitfall Open

K R Anila, S. Kaviya, T Priyakumari, K Jayasree · 2025

NUT carcinoma is a rare, aggressive, undifferentiated carcinoma characterized by NUTM1 gene rearrangement. It was formerly termed NUT midline carcinoma due to its propensity to occur in midline anatomical structures. While initially believ…

Survival and prognostic factors of childhood Ewing sarcoma – Experience from a cancer center in South India Open

Binitha Rajeswari, V.R. Prasanth, Priyakumari Thankamony, Manjusha Nair, Guruprasad Chellappan Sojamani , et al. · 2025

Background: Childhood Ewing sarcoma (ES) – both osseous and extraosseous – has good outcomes with aggressive treatment that includes chemotherapy, surgery, and radiation therapy (RT). In this paper, we report our experience on the survival…

Clinico-pathologic profile and pattern of p53 expression of lung adenocarcinoma in non-smokers and smokers in a tertiary cancer centre Open

Puj Ketul S, Sindhu Nair P, Renu Sukumaran, AL Lijeesh, K Jayasree · 2024

Background: Lung cancer is the most common cause of cancer mortality worldwide. Smoking is undoubtedly the major risk factor of lung cancer in both genders. Adenocarcinoma is the most common form of lung cancer in both men and women and th…

Angiosarcoma of the head and neck: A clinicopathologic study with special emphasis on diagnostic pitfalls Open

Jayapriya Gangadharan, Anitha Mathews, Sindhu N. Prasanna Kumary, Thara Somanathan, K Jayasree , et al. · 2024

Background and Aims: Angiosarcoma (AS) is a rare malignant vascular tumor that phenotypically and functionally recapitulate normal endothelium. They constitute approximately 2–4% of soft tissue sarcomas. We present 36 cases of head and nec…

SMARCB1 deficient sinonasal carcinoma Open

KR Anila, V Ginju, V. P. Vishnu, Rejnish Kumar, K Jayasree · 2023

SMARCB1 deficient sinonasal carcinomas are rare neoplasms, classified under sinonasal undifferentiated carcinomas by the fourth edition of the World Health Organization (WHO) classification of head and neck tumors. It is characterized immu…

Stage migration and treatment outcome in carcinoma tongue – A comparison of seventh and eighth AJCC pathological staging systems Open

R P George, Aparna Mullangath Prakasan, KR Anila, K. M. Jagathnath Krishna, Elizabeth Mathew Iype , et al. · 2022

Background: The eighth edition of the American Joint Committee on Cancer (AJCC) for oral cancer has incorporated additional pathological features like depth of invasion (DOI) and extranodal extension (ENE) into T and N staging. The incorpo…

Aggressive histopathological variants of papillary thyroid carcinoma, diagnostic challenge, and clinical significance—A case series Open

PK Pravanya, KR Anila, Shaji Thomas, A Sreekumar, K Jayasree · 2022

Papillary thyroid carcinoma is the most common form of thyroid cancer and is usually associated with a good outcome. However, there are some aggressive variants wherein the prognosis may not be as good as for a conventional papillary thyro…

Immunohistochemical Expression of PD-L1 and MDR1 in Breast Tumors: Association with Clinico-Pathological Parameters and Treatment Outcome Open

Gisha Rose Antony, Paul Augustine, TP Sulfath, BL Ajeesh, K Jayasree , et al. · 2022

Antitumor immune evasion is a hallmark for the development and progression of cancer. Tumor cells adopt various mechanisms to escape the host immune system recognition. One such mechanism is the over expression of programmed death ligand (…

Lymphocytic Thyroiditis- Association between Cytology and Biochemical Findings Open

Priya P Kartha, Aysha Ali, K Jayasree, Balachandran Sreeram · 2022

Introduction: Hashimoto’s thyroiditis otherwise called as chronic lymphocytic thyroiditis is the most common cause of hypothyroidism and one of the most common thyroid lesions in Fine Needle Aspiration Cytology (FNAC). Diagnosis depends on…

Immunoexpression of TTF1 and p63 Differentiates Lung Adenocarcinomas in Sputum Samples Open

VS Veena, Valliamma N. Saritha, Preethi Sara George, Kumar B. Rajan, K Jayasree , et al. · 2021

Context: Differentiating NSCLC as either adeno or squamous type and identification of Epidermal Growth Factor Receptor (EGFR) mutations is clinically relevant for lung cancer patients for selecting treatment. Thyroid transcription factor-1…

Sinonasal mucosal melanoma: A 9-year experience from a tertiary-cancer centre in South India Open

KR Anila, ElizabethMathew Iype, Malu Rafi, Thara Somanathan, K Jayasree · 2020

Sinonasal tract malignancies are uncommon, representing not more than 5% of all head and neck neoplasm. Primary sinonasal mucosal melanomas (SNMM) are rare and constitute 1% of all melanomas and about 4% of all sinonasal tumors. Mucosal me…

Osteosarcoma and LCH in children – clinical and radiological mimicks Open

Trivedi Maharshi, Thankamony Priya kumari, C.S. Guruprasad, Binitha Rajeswari, Manjusha Nair , et al. · 2019

Sinonasal nonsalivary-type adenocarcinoma: A 9-year experience from a tertiary cancer center in South India Open

KR Anila, Kunnambath Ramadas, ElizabethMathew Iype, TR Preethi, Anitha Mathews , et al. · 2019

Background: Sinonasal tract malignancies are uncommon, representing not more than 5% of all head and neck neoplasm. Primary non-salivary type adenocarcinomas of the sinonasal tract are rare and may originate from respiratory surface epithe…

Histopathological Study of the Relationship of Columnar Cell Lesions to Carcinoma Breast Open

Surekha Vijayan M, K Jayasree, G Krishna, Jayaraman M.B · 2019

Introduction: Columnar cell lesions (CCLs) of the breast comprise a spectrum of benign to atypical entities that have in common variably dilated terminal duct lobular units lined by columnar epithelial cells with prominent apical cytoplasm…

Papillary carcinoma thyroid serving as recipient tumor to carcinoma breast: A rare example of tumor-to-tumor metastasis Open

AnilaKunjulekshmyamma Raveendrannair, Anitha Mathews, BipinT Varghese, K Jayasree · 2019

A 36-year-old female presented with lump in the left breast of 2 months duration. Fine-needle aspiration cytology (FNAC) and trucut biopsy confirmed the diagnosis of carcinoma. Clinically, it was T3N1Mx disease. Computed tomography (CT) of…

Immunocytochemistry on sputum samples predicts prognosis of lung cancer Open

K. Sujathan, VS Veena, P.S. George, K Rajan, K Chandramohan , et al. · 2019

This is the first report of immunocytochemistry of a panel of markers on cells exfoliated in sputum samples which suggests that analysis of immunocytochemical markers in sputum samples can be attempted as a cost-effective and reliable pred…

Cyclooxygenase-2 expression in squamous cell carcinoma of larynx: association with clinico-pathological factors and treatment outcomes Open

Elizabeth Mathew Iype, Rajan Balakrishna, Lakshmi Subhadradevi, Jissa Vinoda Thulaseedharan, Rajesh Kumar Singh , et al. · 2018

Background: Squamous cell carcinoma (SCC) of larynx is widely prevalent in India and is one of the leading cancers in males. Tumor Cyclooxygenase-2 (Cox-2) expression can be used as a prognostic and predictive marker in la…

Role of rapid on-site evaluation in CT-guided fine needle aspiration cytology of lung nodules Open

K R Anila, Nileena Nayak, M Venugopal, K Jayasree · 2018

CT-guided FNA with ROSE is a safe and useful tool in the diagnostic work-up of lung cancer patients. A multidisciplinary approach along with onsite evaluation of adequacy will increase the diagnostic utility of cytology in lung lesions.

Is extracorporeal irradiation and re-implantation a good enough alternative to implants in paediatric bone tumors? Open

Deepthi Boddu, T. Priya Kumari, K Jayasree, Subin Sugath Aswinkumar, C.S. Guruprasad , et al. · 2018

Tubulocystic renal cell carcinoma: An entity related to papillary renal cell carcinoma? Open

KR Anila, Anitha Mathews, Paul Augustine, E Krithika, K Jayasree · 2018

A 48-year-old man presented to our surgical oncology division with incidentally detected abdominal mass. On examination, a ballotable swelling was present in the right lumbar region. His imaging studies showed a large multicystic mass in t…

Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid gland: Not so indolent a neoplasm? Open

AnilaKunjulekshmi Amma Raveendran Nair, NebuA George, Rejnish Kumar, A Sreekumar, K Jayasree · 2018

A 58-year-old female, a known diabetic and hypertensive, presented with left-sided swelling on the anterior aspect of the neck of 1-year duration, which was rapidly increasing in size for the past 6 months. She was on Eltroxin for hypothyr…

Diabetic mastopathy: An entity clinically mimicking malignancy; review of a series of three cases Open

KR Anila, K Chandramohan, SumodMathew Koshy, K Jayasree · 2018

Diabetic mastopathy is an unusual lesion affecting the breast of patients with longstanding diabetes mellitus (DM). This lesion presents as large hard masses, leading to clinical suspicion of malignancy, and may result in unnecessary surge…

DNA Replication Licensing Proteins for Early Detection of Lung Cancer Open

VS Veena, K Rajan, V.N. Saritha, Preethi Sara George, K Chandramohan , et al. · 2017

Background: To identify and characterize malignant and premalignant cells in sputum and matched tissue samples with reference to expression of minichromosome maintenance proteins (MCM2, MCM5) and cell division cycle protein 6 (CDC 6) and t…

Cytology of Malignant Lesions of Liver: An Institutional Study Open

K Jayasree, Jayalaxmi · 2017

Rare cancers Open

Raveendran K. Pillai, K Jayasree · 2017

Rare cancers account for about 22 per cent of all cancers diagnosed worldwide, disproportionately affecting some demographic groups, with an occurrence of less than 6 per 100,000 individuals annually. Many rare cancers in adults, adolescen…

The Bethesda System for Reporting Thyroid Cytopathology with Histological Correlation Open

K Jayasree, Jayalaxmi, C. Priyanka · 2017

ANOMALOUS ORIGIN OF CORONARY ARTERIES: ANATOMICAL STUDY AND CLINICAL CORRELATES Open

K Jayasree, PR Ashalatha · 2016

AIMS AND OBJECTIVESThe arterial supply of the heart is obtained by the two coronary arteries, right and left, which originate respectively from the right and left aortic sinuses of ascending aorta.Considering all congenital cardiac anomali…

Cytomorphologic spectrum of lymphocytic thyroiditis and correlation between cytological grading and biochemical parameters Open

KR Anila, Nileena Nayak, K Jayasree · 2016

Lymphocytic infiltration of thyroid follicles is pathognomonic of lymphocytic thyroiditis. Positivity for antithyroid antibodies is strongly associated with HT but no correlation was observed between the grades of thyroiditis and the level…

Green urine and extrapyramidal symptoms Open

R. Ram, K Jayasree, B Sangeetha, V Chaitanya, BV Subramanyam , et al. · 2016

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