Perumal Kaliraj
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View article: Enhancing Tuberculosis Treatment Adherence: Evaluating the Efficacy of the Support for Treatment Adherence and Medication Protocols (STAMP) Device for Automatic Dispensing and Real-Time Medication Monitoring
Enhancing Tuberculosis Treatment Adherence: Evaluating the Efficacy of the Support for Treatment Adherence and Medication Protocols (STAMP) Device for Automatic Dispensing and Real-Time Medication Monitoring Open
Tuberculosis (TB) remains a significant global health challenge, necessitating strict adherence to medication for successful treatment and prevention of drug resistance. Adherence to a regular medication regimen is crucial in TB management…
View article: Conformational epitopes of thioredoxin as potential vaccines for lymphatic filariasis
Conformational epitopes of thioredoxin as potential vaccines for lymphatic filariasis Open
Background: Lymphatic filariasis (LF) is a neglected tropical disease (NTD) that threatens nearly half of the endemic population in India. India accounts for 40% of the world's LF burden. Currently, there may be up to 31 million microfilar…
View article: Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in experimental mice model
Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in experimental mice model Open
View article: Elucidation of immunological response and its regulatory network by P-TUFT-ALT-2: a promising fusion protein vaccine for human lymphatic filariasis
Elucidation of immunological response and its regulatory network by P-TUFT-ALT-2: a promising fusion protein vaccine for human lymphatic filariasis Open
Human lymphatic filariasis, a mosquito-borne neglected tropical parasitic disease, needs an early development of prophylactic agents such as a vaccine for its successful elimination. Our earlier study suggested the enhanced immunological r…
View article: Cloning, expression and characterization of <i>Brugia malayi</i> abundant larval protein transcript-2 (BmALT-2) expressed in <i>Pichia pastoris</i>
Cloning, expression and characterization of <i>Brugia malayi</i> abundant larval protein transcript-2 (BmALT-2) expressed in <i>Pichia pastoris</i> Open
Besides mass drug administration, successful elimination of human lymphatic filariasis, a mosquito-borne tropical parasitic disease, requires developing other suitable prophylactic agents such as vaccines. The Brugia malayi abundant larval…
View article: Effect of muramyl dipeptide and alum adjuvants on immunization with Filarial multi antigen peptide vaccine in mice model
Effect of muramyl dipeptide and alum adjuvants on immunization with Filarial multi antigen peptide vaccine in mice model Open
Summary Filarial thioredoxin and transglutaminase are enzymes that are secreted throughout the lifecycle of the parasites which are mandatory for the survival of the parasite. They are reported to be promising vaccine candidates, yet the l…
View article: Standardized r<i>Wb</i>SXP-1 assay for the slide method of samples.
Standardized r<i>Wb</i>SXP-1 assay for the slide method of samples. Open
Four different clinical groups MF (n = 20), EN (n = 20), CP (n = 20) and NEN (n = 10) were used for the assay. The MF samples had high significance with a P value of <0.0001. The horizontal bars represents the mean value of each group. The…