A. K. M. Mohiuddin
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View article: Transcriptomics analysis unveils the complex interplay between diabetes and hypertension in regulating renal cell carcinoma pathway followed by pancreatic metastasis
Transcriptomics analysis unveils the complex interplay between diabetes and hypertension in regulating renal cell carcinoma pathway followed by pancreatic metastasis Open
View article: Biodegradation of plastics and pesticides by soil bacteria in Bangladesh: Insights into antibiotic resistance and potential therapeutic targets
Biodegradation of plastics and pesticides by soil bacteria in Bangladesh: Insights into antibiotic resistance and potential therapeutic targets Open
Soil bacteria exhibit varying degrees of tolerance to different concentrations of pesticides and plastics, and some possess the ability to degrade them, which is crucial for bioremediation. However, the multidrug-resistant properties of th…
View article: Highly Effective Removal of Ciprofloxacin from Aqueous Solution Using Graphene Oxide Functionalized Zeolite
Highly Effective Removal of Ciprofloxacin from Aqueous Solution Using Graphene Oxide Functionalized Zeolite Open
Graphene oxide (GO) functionalized zeolites (ZGO) was synthesized as an adsorbent for swift and successful removal of the ciprofloxacin (CIP) antibiotic. The as-prepared nanocomposite was characterized by field emission scanning electron m…
View article: Relationship between Induction of Novel Somaclonal Variants and Types of Organogenesis in Muskmelon (Cucumis melo L.)
Relationship between Induction of Novel Somaclonal Variants and Types of Organogenesis in Muskmelon (Cucumis melo L.) Open
View article: Modern Approaches to Protein Constructions: A Comprehensive Review of Computational Tools and Databases for De Novo Protein Design and Engineering
Modern Approaches to Protein Constructions: A Comprehensive Review of Computational Tools and Databases for De Novo Protein Design and Engineering Open
The field of protein engineering has witnessed transformative advancements, with computational tools and databases driving novel innovations in de novo protein design. This review consolidates and critiques a comprehensive range of modern …
View article: Production of Plant Garbage Juice and Its Effects on Plant Growth, Antibacterial Activity and Soil Reconditioning
Production of Plant Garbage Juice and Its Effects on Plant Growth, Antibacterial Activity and Soil Reconditioning Open
Plant Garbage Juice (PGJ) is a highly concentrated bio-molecular solution. It contains water and bio-molecules such as acetic acid, sugar, proteins, alcohol, as well several enzymes like protease, amylase, lipase, and papain. It is promote…
View article: Optimization of Plant Growth Regulators for Efficient Embryogenic Callus Induction and Subsequent Plant Regeneration in Two Indigenous Aromatic Rice Varieties of Bangladesh
Optimization of Plant Growth Regulators for Efficient Embryogenic Callus Induction and Subsequent Plant Regeneration in Two Indigenous Aromatic Rice Varieties of Bangladesh Open
An efficient regeneration protocol via somatic embryogenesis for two aromatic Indica rice varieties, Kalijira and Tulshimala was developed. Using mature, dehusked seeds, the process involved callus initiation, embryo development and plant …
View article: Structure‐based pharmacophore modeling for precision inhibition of mutant <scp>ESR2</scp> in breast cancer: A systematic computational approach
Structure‐based pharmacophore modeling for precision inhibition of mutant <span>ESR2</span> in breast cancer: A systematic computational approach Open
Background Breast cancer, a leading cause of female mortality, is closely linked to mutations in estrogen receptor beta (ESR2), particularly in the ligand‐binding domain, which contributed to altered signaling pathways and uncontrolled cel…
View article: Investigating the role of hypothetical protein (AAB33144.1) in HIV-1 virus pathogenicity: A comparative study with FDA-Approved inhibitor compounds through In silico analysis and molecular docking
Investigating the role of hypothetical protein (AAB33144.1) in HIV-1 virus pathogenicity: A comparative study with FDA-Approved inhibitor compounds through In silico analysis and molecular docking Open
This study suggests that the annotated hypothetical protein related to protease action, which may be useful in viral genetics and drug discovery.
View article: Gene silencing of <i>Helicobacter pylori</i> through newly designed <scp>siRNA</scp> convenes the treatment of gastric cancer
Gene silencing of <i>Helicobacter pylori</i> through newly designed <span>siRNA</span> convenes the treatment of gastric cancer Open
Background Helicobacter pylori is a gastric pathogen that is responsible for causing chronic inflammation and increasing the risk of gastric cancer development. It is capable of persisting for decades in the harsh gastric environment becau…
View article: Mpropred: A machine learning (ML) driven Web-App for bioactivity prediction of SARS-CoV-2 main protease (Mpro) antagonists
Mpropred: A machine learning (ML) driven Web-App for bioactivity prediction of SARS-CoV-2 main protease (Mpro) antagonists Open
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic emerged in 2019 and still requiring treatments with fast clinical translatability. Frequent occurrence of mutations in spike glycoprotein of SARS-CoV-2 led the consi…
View article: Screening of Preliminary Phytochemicals, Molecular Identification, and Antimicrobial and Anti‐Inflammatory Activity of <i>Justicia</i> g<i>endarussa</i>
Screening of Preliminary Phytochemicals, Molecular Identification, and Antimicrobial and Anti‐Inflammatory Activity of <i>Justicia</i> g<i>endarussa</i> Open
Justicia gendarussa is a well‐known medicinal plant from ancient times that has been using to treat a variety of ailments. The main objectives of the current study were to assess the phytochemicals, molecular identification of the plant, a…
View article: Pathogen-driven gene expression patterns lead to a novel approach to the identification of common therapeutic targets
Pathogen-driven gene expression patterns lead to a novel approach to the identification of common therapeutic targets Open
Developing a common medication strategy for disease control and management could be greatly beneficial. Investigating the differences between diseased and healthy states using differentially expressed genes aids in understanding disease pa…
View article: The scenario of knowledge, attitude and practice of the Bangladeshi population towards thalassemia prevention: A nationwide study
The scenario of knowledge, attitude and practice of the Bangladeshi population towards thalassemia prevention: A nationwide study Open
Thalassemia is one of the most common life-threatening yet preventable congenital hemoglobin disorders especially in South Asian regions like Bangladesh. It has become a rising public health concern for Bangladesh as 6–12% of the populatio…
View article: Energy Efficiency and Optimization of Buildings for Sustainable Development in Malaysia
Energy Efficiency and Optimization of Buildings for Sustainable Development in Malaysia Open
Energy is the core requirement for all sectors to operate efficiently and successfully. Many sectors in Malaysia progressively uses more energy as its economy grows rapidly. The main four energy expending sectors are Industry, transportati…
View article: Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies
Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies Open
Colorectal cancer (CRC) is the second most deadly cancer. Global incidence and mortality are likely to be increased in the coming decades. Although the deaths associated with CRC are very high in high-income countries, the incidence and fa…
View article: A Review of HVAC System Optimization and Its Effects on Saving Total Energy Utilization of a Building
A Review of HVAC System Optimization and Its Effects on Saving Total Energy Utilization of a Building Open
The paper illustrates the review on the optimizations studies of HVAC systems based on three main methods – HVAC operational variables optimization, optimization of control parameters in HVAC system and parameter optimization in building m…
View article: Lack of knowledge is the leading key for the growing cervical cancer incidents in Bangladesh: A population based, cross-sectional study
Lack of knowledge is the leading key for the growing cervical cancer incidents in Bangladesh: A population based, cross-sectional study Open
Introduction Cervical cancer is the second most common gynecological cancer in Bangladesh. Lack of awareness of screening methods, risk factors, and symptoms may lead to presenting most cervical cancers at an advanced stage. We investigate…
View article: Pathogenic genetic variants from highly connected cancer susceptibility genes confer the loss of structural stability
Pathogenic genetic variants from highly connected cancer susceptibility genes confer the loss of structural stability Open
View article: Evaluation of knowledge, awareness and attitudes towards breast cancer risk factors and early detection among females in Bangladesh: A hospital based cross-sectional study
Evaluation of knowledge, awareness and attitudes towards breast cancer risk factors and early detection among females in Bangladesh: A hospital based cross-sectional study Open
Background Breast cancer (BCa) is a leading cause of mortality among women in Bangladesh. Many young women in Bangladesh have poor knowledge about breast cancer screening, including risk factors, warning signs/symptoms, diagnosis and early…
View article: Knowledge, awareness and preventive practices of dengue outbreak in Bangladesh: A countrywide study
Knowledge, awareness and preventive practices of dengue outbreak in Bangladesh: A countrywide study Open
Background Dengue, the mosquito borne disease has become a growing public health threat in Bangladesh due to its gradual increasing morbidity and mortality since 2000. In 2019, the country witnessed the worst ever dengue outbreak. The pres…
View article: Appraisal of Heavy Metal Presence and Water Quality having Microbial Load and Associated Human Health Risk: A study on tube-well water in Nalitabari township of Sherpur district, Bangladesh
Appraisal of Heavy Metal Presence and Water Quality having Microbial Load and Associated Human Health Risk: A study on tube-well water in Nalitabari township of Sherpur district, Bangladesh Open
This article is based on a study aimed to determine physiochemical parameters, fecal coliform, total coliforms, heterotrophic plate count, arsenic, iron and lead of water to evaluate their effects on human health. Analysis was carried out …
View article: Designing potential siRNA molecule for the nucleocapsid(N) gene silencing of different SARS-CoV-2 strains of Bangladesh: Computational approach
Designing potential siRNA molecule for the nucleocapsid(N) gene silencing of different SARS-CoV-2 strains of Bangladesh: Computational approach Open
View article: Public Perceptions and Attitudes of Bangladeshi Population towards Thalassemia Prevention: A Nationwide Study
Public Perceptions and Attitudes of Bangladeshi Population towards Thalassemia Prevention: A Nationwide Study Open
Background: Thalassemia is one of the most common life-threatening yet preventable congenital hemoglobin disorders especially in South Asian regions like Bangladesh. It has become a rising public health concern for Bangladesh as 6-12% of t…
View article: Newly designed analogues from SARS-CoV inhibitors mimicking the druggable properties against SARS-CoV-2 and its novel variants
Newly designed analogues from SARS-CoV inhibitors mimicking the druggable properties against SARS-CoV-2 and its novel variants Open
Three designed inhibitors with potential inhibition efficacy against the emerging variants of SARS coronavirus-2 (SARS-CoV-2).
View article: Antibacterial Activity of Eight Medicinal Plants against Multidrug Resistant Escherichia coli and Salmonella spp. isolated from Broiler Meat
Antibacterial Activity of Eight Medicinal Plants against Multidrug Resistant Escherichia coli and Salmonella spp. isolated from Broiler Meat Open
The excess use of antimicrobial agents in the poultry industry is a significant reason for the gradual spread and increasing level of multidrug resistance bacteria. This article is based on a study in which the antibacterial activity of aq…
View article: Antibacterial Activity of Eight Medicinal Plants against Multidrug Resistant Escherichia coli and Salmonella spp. isolated from Broiler Meat
Antibacterial Activity of Eight Medicinal Plants against Multidrug Resistant Escherichia coli and Salmonella spp. isolated from Broiler Meat Open
The excess use of antimicrobial agents in the poultry industry is a significant reason for the gradual spread and increasing level of multidrug resistance bacteria. This article is based on a study in which the antibacterial activity of aq…
View article: Cytotoxicity, antioxidant, antimicrobial studies and phytochemical screening of endophytic fungi isolated from Justicia gendarussa
Cytotoxicity, antioxidant, antimicrobial studies and phytochemical screening of endophytic fungi isolated from Justicia gendarussa Open
View article: Molecular characterization and functional annotation of a hypothetical protein (SCO0618) of Streptomyces coelicolor A3(2)
Molecular characterization and functional annotation of a hypothetical protein (SCO0618) of Streptomyces coelicolor A3(2) Open
Streptomyces coelicolor is a gram-positive soil bacterium which is well known for the production of several antibiotics used in various biotechnological applications. But numerous proteins from its genome are considered hypothetical protei…
View article: Prevalence, severity and risk factors of food allergy and food addiction among the people of Tangail district, Bangladesh
Prevalence, severity and risk factors of food allergy and food addiction among the people of Tangail district, Bangladesh Open
Background: Food allergy is an abnormal response of some particular foods triggered by the body’s immune system. Food addiction which generally shares a similar neurobiological and behavioral framework with substance addiction like foods. …