Kalyanaraman Kumaran
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View article: Unveiling the Silent Struggle: Depression and Healthcare Utilization Among the Elderly in Rural South India
Unveiling the Silent Struggle: Depression and Healthcare Utilization Among the Elderly in Rural South India Open
Background: Depression is one of the mental health issues that has a significant worldwide impact. Findings: Majority of the cases of depression are either underdiagnosed or misdiagnosed as most of the time the symptoms are masked by cogni…
View article: Emotional and instrumental social support and older adults’ depressive symptoms: collaborative individual participant data meta-analysis of 11 population-based studies of aging
Emotional and instrumental social support and older adults’ depressive symptoms: collaborative individual participant data meta-analysis of 11 population-based studies of aging Open
Social support is considered a protective factor against depression, but there are inconsistent findings regarding social support and depression in older adults. We aimed to clarify the association between emotional and instrumental social…
View article: Examining the impact of maternal experiences of domestic violence on the mental health of their adolescent children in India
Examining the impact of maternal experiences of domestic violence on the mental health of their adolescent children in India Open
Background Domestic violence (DV) is experienced by one in three women in India and is linked to poor mental health outcomes. We hypothesize that maternal experiences of DV can have negative impacts on the mental health of their children. …
View article: How Are Global Diet Quality Scores at 9 Years Associated With Cardiometabolic Disease Risk in Early Adolescence in Mysore, India?
How Are Global Diet Quality Scores at 9 Years Associated With Cardiometabolic Disease Risk in Early Adolescence in Mysore, India? Open
Objective The purpose of the study was to assess Global Diet Quality Score (GDQS) at age 9.5 years and associated risk of cardiometabolic outcomes at 13.5 years in a birth cohort in Mysore, India. Background Assessing relationships between…
View article: Challenges with developing nutritional recommendations to improve pregnancy outcomes
Challenges with developing nutritional recommendations to improve pregnancy outcomes Open
Susan Ozanne and colleagues argue that strategies are urgently needed to translate knowledge about how maternal nutrition affects children’s long term health into improved population health outcomes
View article: Prospective harmonisation of four international randomised controlled trials in Canada, China, India and South Africa: the Healthy Life Trajectories Initiative
Prospective harmonisation of four international randomised controlled trials in Canada, China, India and South Africa: the Healthy Life Trajectories Initiative Open
Objectives The Healthy Life Trajectories Initiative (HeLTI) is an international multistudy consortium that supports the development and integration of four randomised controlled trials (RCTs) conducted in South Africa, India, China and Can…
View article: Artificial neural network for performance modelling of shape memory alloy
Artificial neural network for performance modelling of shape memory alloy Open
In recent years, significant strides in technological advancement have revolutionized our lifestyles, driving a surge in demand for multifunctional and intelligent materials. Among these materials, Shape Memory Alloy (SMA) stands out for i…
View article: Examining the impact of maternal experiences of domestic violence on adolescent mental health disorders in India
Examining the impact of maternal experiences of domestic violence on adolescent mental health disorders in India Open
Background Domestic violence (DV) is experienced by one in three women in India and is linked to poor mental health outcomes. We hypothesize that maternal experiences of DV can have negative impacts on the mental health of their children. …
View article: IJCM_397A: A Cross-Sectional Study on Dietary Intake In Relation To Sleep Quality Among Undergraduate Engineering Students
IJCM_397A: A Cross-Sectional Study on Dietary Intake In Relation To Sleep Quality Among Undergraduate Engineering Students Open
Background: Sleep is an important resting state and essential part of life that could have effect on many aspects of life. Life style factors such as physical activity and consumption of certain foods have effect on quality and quantity of…
View article: Childhood adversities characterize the heterogeneity in the brain pattern of individuals during neurodevelopment
Childhood adversities characterize the heterogeneity in the brain pattern of individuals during neurodevelopment Open
Background Several factors shape the neurodevelopmental trajectory. A key area of focus in neurodevelopmental research is to estimate the factors that have maximal influence on the brain and can tip the balance from typical to atypical dev…
View article: DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood
DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood Open
Human height is strongly influenced by genetics but the contribution of modifiable epigenetic factors is under-explored, particularly in low and middle-income countries (LMIC). We investigate links between blood DNA methylation and child h…
View article: Developing Policy for the Healthy Life Trajectories Initiative: Going from National to International
Developing Policy for the Healthy Life Trajectories Initiative: Going from National to International Open
Background: Scientific research is becoming an increasingly collaborative and global venture. The Healthy Life Trajectories Initiative (HeLTI), for instance, is an international Developmental Origins of Health and Disease research collabor…
View article: Neurocognitive Analysis of Low-level Arsenic Exposure and Executive Function Mediated by Brain Anomalies Among Children, Adolescents, and Young Adults in India
Neurocognitive Analysis of Low-level Arsenic Exposure and Executive Function Mediated by Brain Anomalies Among Children, Adolescents, and Young Adults in India Open
Importance Arsenic, a contaminant of groundwater and irrigated crops, is a global public health hazard. Exposure to low levels of arsenic through food extends well beyond the areas with high arsenic content in water. Objective To identify …
View article: Country-level gender inequality is associated with structural differences in the brains of women and men
Country-level gender inequality is associated with structural differences in the brains of women and men Open
Gender inequality across the world has been associated with a higher risk to mental health problems and lower academic achievement in women compared to men. We also know that the brain is shaped by nurturing and adverse socio-environmental…
View article: Maternal diabetes influences neonatal obesity-adiposity but not in later life Offspring obesity in diabetic pregnancy
Maternal diabetes influences neonatal obesity-adiposity but not in later life Offspring obesity in diabetic pregnancy Open
Background Based on studies in overweight-obese populations, it is tacitly assumed that maternal hyperglycemia is responsible for obesity-adiposity at birth and in later life. Study design Two hospital based case control studies: 1) Neonat…
View article: An intergenerational life-course approach to address early childhood obesity and adiposity: the Healthy Life Trajectories Initiative (HeLTI)
An intergenerational life-course approach to address early childhood obesity and adiposity: the Healthy Life Trajectories Initiative (HeLTI) Open
Background: interactions between genes and early-life exposures during conception, fetal life, infancy, and early childhood have been shown to affect an individual's health later in life. Maternal undernutrition and obesity, gestational di…
View article: DNA methylation at the suppressor of cytokine signaling 3 (<i>SOCS3</i>) gene influences height in childhood
DNA methylation at the suppressor of cytokine signaling 3 (<i>SOCS3</i>) gene influences height in childhood Open
Human height is strongly influenced by genetics but the contribution of modifiable epigenetic factors is under-explored, particularly in low and middle-income countries (LMIC). We investigated links between blood DNA methylation and child …
View article: The 2022 India Report Card on physical activity for children and adolescents
The 2022 India Report Card on physical activity for children and adolescents Open
Active Transportation, Government Strategies, and Overall Physical Activity have improved since the 2018 IRC, a positive trend that needs to be translated to other indicators. However, Sedentary Behavior has consistently worsened, with gra…
View article: Peri-conceptional diet patterns and the risk of gestational diabetes mellitus in South Indian women
Peri-conceptional diet patterns and the risk of gestational diabetes mellitus in South Indian women Open
Objective: To identify peri-conceptional diet patterns among women in Bangalore and examine their associations with risk of gestational diabetes mellitus (GDM). Design: BAngalore Nutrition Gestational diabetes LifEstyle Study, started in J…
View article: Risk clustering and psychopathology from a multi-center cohort of Indian children, adolescents, and young adults
Risk clustering and psychopathology from a multi-center cohort of Indian children, adolescents, and young adults Open
Developmental adversities early in life are associated with later psychopathology. Clustering may be a useful approach to group multiple diverse risks together and study their relation with psychopathology. To generate risk clusters of chi…
View article: Community engagement and context in setting up a multi-faceted longitudinal intervention in rural India: The Healthy Life Trajectories Initiative
Community engagement and context in setting up a multi-faceted longitudinal intervention in rural India: The Healthy Life Trajectories Initiative Open
The Healthy Life Trajectories Initiative programme is a ten-year joint initiative consisting of four separate but harmonised intervention studies in Mysore (India), Johannesburg (South Africa), Shanghai (China) and two provinces in Canada.…
View article: Corrigendum: Pre-conceptional Maternal Vitamin B12 Supplementation Improves Offspring Neurodevelopment at 2 Years of Age: PRIYA Trial
Corrigendum: Pre-conceptional Maternal Vitamin B12 Supplementation Improves Offspring Neurodevelopment at 2 Years of Age: PRIYA Trial Open
[This corrects the article DOI: 10.3389/fped.2021.755977.].
View article: Federated analysis in COINSTAC reveals functional network connectivity and spectral links to smoking and alcohol consumption in nearly 2,000 adolescent brains
Federated analysis in COINSTAC reveals functional network connectivity and spectral links to smoking and alcohol consumption in nearly 2,000 adolescent brains Open
With the growth of decentralized/federated analysis approaches in neuroimaging, the opportunities to study brain disorders using data from multiple sites has grown multi-fold. One such initiative is the Neuromark, a fully automated spatial…
View article: A lifecourse approach to the relationship between lung function and cognition function in late life: findings from the Mysore studies of Natal effect on Ageing and Health (MYNAH) in South India
A lifecourse approach to the relationship between lung function and cognition function in late life: findings from the Mysore studies of Natal effect on Ageing and Health (MYNAH) in South India Open
Background: Emerging evidence from high income settings indicates that lung function may be an independent determinant of cognitive abilities in late life. Despite a high burden of chronic lung disorders and neurocognitive disorders, there…
View article: Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns
Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns Open
Size at birth is known to be influenced by various fetal and maternal factors, including genetic effects. South Asians have a high burden of low birth weight and cardiometabolic diseases, yet studies of common genetic variations underpinni…
View article: Babies of South Asian and European Ancestry Show Similar Associations with Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns
Babies of South Asian and European Ancestry Show Similar Associations with Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns Open
Size at birth is known to be influenced by various fetal and maternal factors including genetic effects. South Asians have a high burden of low birthweight and cardiometabolic diseases, yet studies of common genetic variations underpinning…
View article: Babies of South Asian and European Ancestry Show Similar Associations with Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns
Babies of South Asian and European Ancestry Show Similar Associations with Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns Open
Size at birth is known to be influenced by various fetal and maternal factors including genetic effects. South Asians have a high burden of low birthweight and cardiometabolic diseases, yet studies of common genetic variations underpinning…