K. S. Grogg
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View article: Modeling inter‐reader variability in clinical target volume delineation for soft tissue sarcomas using diffusion model
Modeling inter‐reader variability in clinical target volume delineation for soft tissue sarcomas using diffusion model Open
Background Accurate delineation of the clinical target volume (CTV) is essential in the radiotherapy treatment of soft tissue sarcomas. However, this process is subject to inter‐reader variability due to the need for clinical assessment of…
View article: Impact of motion correction on [<sup>18</sup>F]-MK6240 tau PET imaging
Impact of motion correction on [<sup>18</sup>F]-MK6240 tau PET imaging Open
Objective . Positron emission tomography (PET) imaging of tau deposition using [ 18 F]-MK6240 often involves long acquisitions in older subjects, many of whom exhibit dementia symptoms. The resulting unavoidable head motion can greatly deg…
View article: TOPAS-imaging: extensions to the TOPAS simulation toolkit for medical imaging systems
TOPAS-imaging: extensions to the TOPAS simulation toolkit for medical imaging systems Open
Objective . The TOol for PArticle Simulation (TOPAS) is a Geant4-based Monte Carlo software application that has been used for both research and clinical studies in medical physics. So far, most users of TOPAS have focused on radiotherapy-…
View article: Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep
Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep Open
Background Pulmonary atelectasis is frequent in clinical settings. Yet there is limited mechanistic understanding and substantial clinical and biologic controversy on its consequences. The authors hypothesize that atelectasis produces loca…
View article: Performance evaluation of the 5‐Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2‐2012 Standard
Performance evaluation of the 5‐Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2‐2012 Standard Open
The GE Discovery MI PET/CT system has a modular digital detector design allowing three, four, or five detector block rings that extend the axial field‐of‐view (FOV) from 15 to 25 cm in 5 cm increments. This study investigated the performan…
View article: Deterioration of Regional Lung Strain and Inflammation during Early Lung Injury
Deterioration of Regional Lung Strain and Inflammation during Early Lung Injury Open
Mechanical ventilation consistent with clinical practice did not generate excessive regional strain in heterogeneously aerated supine lungs. However, it allowed worsening of spatial strain distribution in these lungs, associated with incre…