Sudesh Prabhakar
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View article: Multidisciplinary Management of Acute Pulmonary Thromboembolism Following Lumbar Spinal Fusion Surgery: A Case Report
Multidisciplinary Management of Acute Pulmonary Thromboembolism Following Lumbar Spinal Fusion Surgery: A Case Report Open
Acute pulmonary thromboembolism (PTE) is a life-threatening complication. Although uncommon, acute PTE can develop silently during prolonged immobility associated with long-duration surgery, particularly in high-risk patients. Prompt diagn…
View article: Associations of lifestyle factors with amyloid pathology in persons without dementia
Associations of lifestyle factors with amyloid pathology in persons without dementia Open
Background The association between lifestyle factors and Alzheimer's disease (AD) pathophysiology remains incompletely understood. Objective The aim of this study was to assess the association of alcohol consumption, smoking behavior, slee…
View article: Depressive Symptoms and Amyloid Pathology
Depressive Symptoms and Amyloid Pathology Open
Importance Depressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association betwee…
View article: Pisa Syndrome in Subacute Sclerosing Panencephalitis: A Case Report and Review of the Literature
Pisa Syndrome in Subacute Sclerosing Panencephalitis: A Case Report and Review of the Literature Open
Ethical standardAll procedures performed in studies involving
View article: Issue Information
Issue Information Open
No abstract is available for this article.
View article: Can Cheiromancy Predict Mean Survival or Fatality of a Patient with Amyotrophic Lateral Sclerosis?
Can Cheiromancy Predict Mean Survival or Fatality of a Patient with Amyotrophic Lateral Sclerosis? Open
Background The past three decades have seen palmistry as an interface to human health. There have been no previously organized attempts in utilizing this knowledge to predict the state of disease. Objective Due to unavailability of any bio…
View article: Presence of allele CYP3A4*16 does not have any bearing on carbamazepine-induced adverse drug reactions in North Indian people with epilepsy
Presence of allele CYP3A4*16 does not have any bearing on carbamazepine-induced adverse drug reactions in North Indian people with epilepsy Open
CYP3A4*16 allele is not represented significantly in North Indian people with CBZ-induced dose-related side effects.
View article: Efficacy of bacopa monnieri (Brahmi) and Donepezil in Alzheimer's Disease and mild cognitive impairment: A randomized double-blind parallel Phase 2b study
Efficacy of bacopa monnieri (Brahmi) and Donepezil in Alzheimer's Disease and mild cognitive impairment: A randomized double-blind parallel Phase 2b study Open
This phase-2 RCT on the efficacy of brahmi vs. donepezil showed no significant difference between them after 1 year of treatment. Larger phase-3 trials, preferably multicentric, are required to find the superiority of brahmi over donepezil.
View article: Are COL1A1 gene polymorphisms associated with anterior cruciate ligament tear in the Indian population? Results of a preliminary case-control study
Are COL1A1 gene polymorphisms associated with anterior cruciate ligament tear in the Indian population? Results of a preliminary case-control study Open
Introduction: Despite the identification of various intrinsic and extrinsic risk factors associated with ACL tear, the exact etiopathogenesis of ACL tear is still incompletely understood.The evidence for association of COL1A1 gene polymorp…
View article: Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease
Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease Open
Introduction Apolipoprotein E ( APOE ) ε4 is the major genetic risk factor for Alzheimer's disease (AD), but its prevalence is unclear because earlier studies did not require biomarker evidence of amyloid β (Aβ) pathology. Methods We inclu…
View article: Prevalence of epilepsy and its association with exposure to Toxocara Canis: A community based, case–control study from rural Northern India
Prevalence of epilepsy and its association with exposure to Toxocara Canis: A community based, case–control study from rural Northern India Open
Our study does not support the association between epilepsy and exposure to T. canis in rural Northern Indian population.
View article: Role of Plasma Clusterin in Alzheimer’s Disease—A Pilot Study in a Tertiary Hospital in Northern India
Role of Plasma Clusterin in Alzheimer’s Disease—A Pilot Study in a Tertiary Hospital in Northern India Open
Our pilot study shows that plasma clusterin is lower in Alzheimer's disease with respect to control population. Plasma clusterin levels and severity of Alzheimer's disease had no significant correlation. There was no difference in plasma c…
View article: Report: Stem cell applications in neurological practice, an expert group consensus appraisal
Report: Stem cell applications in neurological practice, an expert group consensus appraisal Open
In the course of such counselling, it should be emphasized that the information provided by many lay websites might be unsubstantiated. Besides, standard recommendations for the stem cell research, in particular, the application of several…
View article: Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia
Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia Open
Among persons without dementia, the prevalence of cerebral amyloid pathology as determined by positron emission tomography or cerebrospinal fluid findings was associated with age, APOE genotype, and presence of cognitive impairment. These …
View article: Prospective Analysis of 55 Cases of Tuberculosis Meningitis (TBM) in North India
Prospective Analysis of 55 Cases of Tuberculosis Meningitis (TBM) in North India Open
TBM is a serious extrapulmonary form of TB and should arise suspicion in mind of clinician based on clinical, laboratory and radiologic results. Further, a model for prediction of mortality in such patients may be helpful for early interve…
View article: Revisiting the dilution factor as vital parameter for sensitivity of ELISA assay in CSF and Plasma
Revisiting the dilution factor as vital parameter for sensitivity of ELISA assay in CSF and Plasma Open
Negative results from our study highlights the significance of determining the dilution factor as an important parameter for conduct of ELISA.