K. Skeggs
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View article: Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation
Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation Open
View article: Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors
Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors Open
Background The commonest echocardiographic measurement, left ventricular ejection fraction, can not necessarily predict mortality of recipients following heart transplantation potentially due to afterload dependency. Afterload‐independent …
View article: Donor heart ischemic time can be extended beyond 9 hours using hypothermic machine perfusion in sheep
Donor heart ischemic time can be extended beyond 9 hours using hypothermic machine perfusion in sheep Open
View article: Hypothermic Ex Vivo Perfusion of Donor Hearts can Safely Preserve Post‐transplant Cardiac Function in Sheep for 8 Hours
Hypothermic Ex Vivo Perfusion of Donor Hearts can Safely Preserve Post‐transplant Cardiac Function in Sheep for 8 Hours Open
Introduction Heart transplantation (HTx) is the primary therapy for end‐stage heart failure. For HTx, donor hearts are typically preserved on ice in a cooler (devoid of oxygen), termed cold static storage (CSS). CSS beyond 4 hrs increases …
View article: Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model
Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model Open
BSD induced systemic pro-inflammatory responses, characterized by increased neutrophil infiltration and cytokine production in the circulation and BAL fluid, and associated with reduced heart contractile function in ovine model of BSD.
View article: Donor Heart Preservation by Hypothermic Ex Vivo Perfusion - Improved Recipient Survival and Successful Prolongation of Ischemic Time
Donor Heart Preservation by Hypothermic Ex Vivo Perfusion - Improved Recipient Survival and Successful Prolongation of Ischemic Time Open
View article: Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system
Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system Open
Background A lung transplant is the last resort treatment for many patients with advanced lung disease. The majority of donated lungs come from donors following brain death (BD). The endothelin axis is upregulated in the blood and lung of …
View article: The Effects of Different Ventilatory Strategies on Pulmonary Mechanics and Gas Exchange During Heart Transplant: An Experimental Study
The Effects of Different Ventilatory Strategies on Pulmonary Mechanics and Gas Exchange During Heart Transplant: An Experimental Study Open
View article: Metabolic and Mitochondrial Alterations Following Brain Death and Heart Transplantation
Metabolic and Mitochondrial Alterations Following Brain Death and Heart Transplantation Open
View article: 120 Hypothermic Ex Vivo Perfusion of Brain Dead Donor Hearts Improves Survival, Systemic Inflammation and Cardiac Function Following Heart Transplantation
120 Hypothermic Ex Vivo Perfusion of Brain Dead Donor Hearts Improves Survival, Systemic Inflammation and Cardiac Function Following Heart Transplantation Open
View article: 121 Hypothermic Ex Vivo Perfusion Preserves Post-Transplant Donor Cardiac Function
121 Hypothermic Ex Vivo Perfusion Preserves Post-Transplant Donor Cardiac Function Open