K. Sasikumar
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View article: When the usual is unusual – An uncommon presentation of enteric fever
When the usual is unusual – An uncommon presentation of enteric fever Open
Typhoid fever has an estimated worldwide prevalence of 12–33 million cases with high incidence in India, especially in urban centres. Hemophagocytic lymphohistiocytosis is a rare complication of typhoid fever, which may be fatal if untreat…
View article: Temporal Dynamics and Seasonal Incidence of Major Insect Pests in Castor (Ricinus communis L.) under Tropical Agro ecosystem of Tamil Nadu
Temporal Dynamics and Seasonal Incidence of Major Insect Pests in Castor (Ricinus communis L.) under Tropical Agro ecosystem of Tamil Nadu Open
An intensive four-year field study (2013–2017) was conducted at Tapioca and Castor Research Station, Tamil Nadu Agricultural University, to monitor the seasonal incidence and population dynamics of major insect pests infesting castor (Rici…
View article: Field Evaluation of Integrated Management Modules for Rugose Spiralling Whitefly (Aleurodicus rugioperculatus) in Coconut Ecosystem
Field Evaluation of Integrated Management Modules for Rugose Spiralling Whitefly (Aleurodicus rugioperculatus) in Coconut Ecosystem Open
An on-farm trial was conducted in Periyapudur village, Salem district, Tamil Nadu, to evaluate integrated management modules against rugose spiralling whitefly (RSW) (Aleurodicus rugioperculatus) infesting coconut palms. Three modules comb…
View article: Supplementary Data from Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy
Supplementary Data from Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy Open
Supplementary results
View article: Data from Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy
Data from Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy Open
Cancer genomic studies have identified frequent alterations in genes encoding components of the SWI/SNF chromatin remodeling complex, including SMARCA4 and ARID1A. Importantly, clinical reports indicate that SMARCA4-mutant lung cancers res…
View article: Discovery of Novel, Potent, and Orally Bioavailable SMARCA2 Proteolysis-Targeting Chimeras with Synergistic Antitumor Activity in Combination with Kirsten Rat Sarcoma Viral Oncogene Homologue G12C Inhibitors
Discovery of Novel, Potent, and Orally Bioavailable SMARCA2 Proteolysis-Targeting Chimeras with Synergistic Antitumor Activity in Combination with Kirsten Rat Sarcoma Viral Oncogene Homologue G12C Inhibitors Open
Cancer genomic studies have identified frequent mutations in subunits of the SWI/SNF chromatin remodeling complex, including SMARCA4 in nonsmall cell lung cancer with a frequency of up to 33% in advanced-stage disease, making it the most f…
View article: Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy
Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy Open
Cancer genomic studies have identified frequent alterations in genes encoding components of the SWI/SNF chromatin remodeling complex, including SMARCA4 and ARID1A. Importantly, clinical reports indicate that SMARCA4-mutant lung cancers res…
View article: Quality Assessment and Evaluation in Traditional Landraces of Rice (Oryza sativa)
Quality Assessment and Evaluation in Traditional Landraces of Rice (Oryza sativa) Open
After the Green Revolution, the increase in the choice of modern varieties at the expense of landraces has become a major cause of varietal loss. The preference, choice, and the economy of rice (Oryza sativa L.) largely depend on its physi…
View article: Trend Analysis of Blended Learning Research Output from Scopus: A Scientometric Study
Trend Analysis of Blended Learning Research Output from Scopus: A Scientometric Study Open
This research study is a scientometric analysis of blended learning research output indexed in Scopus from 2015 to 2023, revealing significant growth in publications and citation metrics. The analysis indicates an upward trend in records, …
View article: Nanotechnology-based Materials for Sustainable Pest and Disease Control in Agriculture
Nanotechnology-based Materials for Sustainable Pest and Disease Control in Agriculture Open
Nanotechnology is emerging as a transformative tool in agriculture, offering innovative approaches for sustainable pest and disease management. The incorporation of nanomaterials into agricultural practices has the potential to address the…
View article: Enhancing Blackgram (Vigna mungo L.) Productivity through Good Agricultural Practices in Tamil Nadu, India
Enhancing Blackgram (Vigna mungo L.) Productivity through Good Agricultural Practices in Tamil Nadu, India Open
Large scale pulse seed production demonstrations on black gram under the TN IAMP scheme conducted by Agricultural College and Research Institute, Tamil Nadu Agricultural University, Vazhavachanur, Tiruvannamalai district, Tamil Nadu, India…
View article: Evaluation of IPM Module for the Management of Key Insect Pests in Chilli
Evaluation of IPM Module for the Management of Key Insect Pests in Chilli Open
Chilli is a crop cultivated in tropical and subtropical regions of India, and the crop is attacked by a multitude of pests at different crop stages. The present study revealed that field experiments were laid out with three treatments, viz…
View article: Status of Invasive Species of Thrips, Thrips Parvispinus (Karny) Infesting Chilli and Investigation Studies on IPDM Package in Dharmapuri Districts, Tamil Nadu, India
Status of Invasive Species of Thrips, Thrips Parvispinus (Karny) Infesting Chilli and Investigation Studies on IPDM Package in Dharmapuri Districts, Tamil Nadu, India Open
Roving survey results revealed that mean population of thrips, mite population and tospovirus incidence was recorded to be 1.63, 0.68 & 2.05 and 1.88, 0.74 & 1.57 in Pennagaram and Palacode blocks. In the field experiments, mean population…
View article: Influence of IBA and NAA on Rooting of Terminal Cuttings of Chrysanthemum (Dendranthema grandiflora L.)
Influence of IBA and NAA on Rooting of Terminal Cuttings of Chrysanthemum (Dendranthema grandiflora L.) Open
The present investigation was conducted at the Agricultural College and Research Institute, Vazhavachanur, Tiruvannamalai to study the effect of Indole-3-Butyric Acid (IBA) and Naphthalene Acetic Acid (NAA) on the rooting of terminal cutti…
View article: Effect of Nutritional and Environmental Conditions on Growth of Colletotrichum gloeosporioides Causing Anthracnose of Anthurium
Effect of Nutritional and Environmental Conditions on Growth of Colletotrichum gloeosporioides Causing Anthracnose of Anthurium Open
Isolates of Collectotrichum gloeosporioides causing anthracnose disease of anthurium were collected from five different locations of anthurium growing areas of Tamil Nadu and Kerala and their pathogenicity was established. Effect of differ…
View article: Role of Toxin Produced by Alternaria alternata in Leaf Blight of Anthurium and Its Detoxification by Antagonists
Role of Toxin Produced by Alternaria alternata in Leaf Blight of Anthurium and Its Detoxification by Antagonists Open
A study was conducted to investigate the degradation of the phytotoxin produced by the anthurium leaf blight pathogen Alternaria alternata (Fr.) Keissler by antagonistic bacterial and fungal strains. Toxin extracted from leaf blight pathog…
View article: Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors
Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors Open
Cancer genomic studies have identified frequent mutations in subunits of the SWI/SNF chromatin remodeling complex including SMARCA4 in non-small cell lung cancer with a frequency of up to 33% in advanced stage disease, making it the most f…
View article: Effect of Ethyl Methane Sulphonate on Growth and Development of Mulberry (Morus sp.)
Effect of Ethyl Methane Sulphonate on Growth and Development of Mulberry (Morus sp.) Open
Ethyl methanesulfonate (EMS) is a genotoxic agent, it has been widely used as a model compound in experimental work to establish the receptiveness of the test system under examination. EMS induces damage to DNA by a direct mechanism, actin…
View article: Effect on Temperature Influences of the Life Table Studies for Aphid, Aphis craccivora Koch. in Cowpea under Laboratory Condition
Effect on Temperature Influences of the Life Table Studies for Aphid, Aphis craccivora Koch. in Cowpea under Laboratory Condition Open
Aim: To study the life table aphid, Aphis craccivora in cowpea at different temperature. Study Design: Simple random sampling design with two treatments and 12 replications. Place and Duration Study: Agricultural College and Research Insti…
View article: Effect of vermicompost enriched with bacterial endophytes (Azospirillum and Rhizobium) on growth and yield of tomato
Effect of vermicompost enriched with bacterial endophytes (Azospirillum and Rhizobium) on growth and yield of tomato Open
The extensive use of chemical fertilizers has served as a response to the increasing need for crop production in recent decades. While it addresses the demand for food, it has resulted in a decline in crop productivity and a heightened neg…
View article: <i>SMARCA4</i>mutation induces tumor cell-intrinsic defects in enhancer landscape and resistance to immunotherapy
<i>SMARCA4</i>mutation induces tumor cell-intrinsic defects in enhancer landscape and resistance to immunotherapy Open
Cancer genomic studies have identified frequent alterations in components of the SWI/SNF (SWItch/Sucrose Non- Fermenting) chromatin remodeling complex including SMARCA4 and ARID1A . Importantly, clinical reports indicate that SMARCA4 -muta…
View article: Study the Performance of High Yielding Tomato Hybrids in Dharmapuri District, Tamil Nadu, India
Study the Performance of High Yielding Tomato Hybrids in Dharmapuri District, Tamil Nadu, India Open
Tomato (Solanum lycopersicum L.) is an economically important vegetable crop in the globe and affected by various biotic and abiotic stresses to which the plants were exposed during growth. In this study, three tomato hybrids viz., Arka Ab…
View article: Effect of Vermicompost and Organic Fertilizer on Improved Growth, Productivity and Quality of Tomato (Solanum lycopersicum ) Plant
Effect of Vermicompost and Organic Fertilizer on Improved Growth, Productivity and Quality of Tomato (Solanum lycopersicum ) Plant Open
<h2>Abstract</h2>\n<p><strong>Objectives:</strong> This study's objective was to assess the growth and yield of tomato plants (Solanum lycopersicum) grown in vermicompost comprised of various mixtures of …