Vinod Kumar Yadav
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View article: Septic Arthritis of the Knee Due to Chronic Osteomyelitis of the Femur in an Adult: A Case Report
Septic Arthritis of the Knee Due to Chronic Osteomyelitis of the Femur in an Adult: A Case Report Open
Introduction: Adult cases of septic arthritis due to concomitant persistent osteomyelitis are incredibly uncommon. This study describes a rare example of septic arthritis in an adult’s knee joint caused by long-term femur osteomyelitis. A …
View article: Effect of Iron, Zinc and Microbial Inoculants on Soil Health and Nutrient Uptake of Urdbean (Vigna mungo L.) in Vertisols
Effect of Iron, Zinc and Microbial Inoculants on Soil Health and Nutrient Uptake of Urdbean (Vigna mungo L.) in Vertisols Open
An experiment was conducted on urdbean during kharif 2021 at Instructional Farm, College of Agriculture, Ummedganj, Kota (Rajasthan). The experiment comprised 10 treatments viz. (Control, 75 % RDF, 100 % RDF, 75 % RDF + Rhizobium @ 600 g h…
View article: Supplementary Figure 1 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Supplementary Figure 1 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Supplementary Figure 1: CD31 and HandE staining of tumor tissue sections obtained from control and Endoglin shRNA treated cells.
View article: Data from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Data from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Endoglin, a 180-kDa disulfide-linked homodimeric transmembrane receptor protein mostly expressed in tumor-associated endothelial cells, is an endogenous binding partner of GAIP-interacting protein, C terminus (GIPC). Endoglin functions as …
View article: Supplementary Figure 2 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Supplementary Figure 2 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Supplementary Figure 2: CD31 and HandE staining of tumor tissue sections obtained from AP1063-treated and AP1032-treated groups.
View article: Supplementary Materials and Methods from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Supplementary Materials and Methods from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Detailed procedure for the synthesis of lipidated peptides.
View article: Supplementary Figure 1 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Supplementary Figure 1 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Supplementary Figure 1: CD31 and HandE staining of tumor tissue sections obtained from control and Endoglin shRNA treated cells.
View article: Data from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Data from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Endoglin, a 180-kDa disulfide-linked homodimeric transmembrane receptor protein mostly expressed in tumor-associated endothelial cells, is an endogenous binding partner of GAIP-interacting protein, C terminus (GIPC). Endoglin functions as …
View article: Supplementary Figure 2 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Supplementary Figure 2 from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Supplementary Figure 2: CD31 and HandE staining of tumor tissue sections obtained from AP1063-treated and AP1032-treated groups.
View article: Supplementary Materials and Methods from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth
Supplementary Materials and Methods from Inhibition of Endoglin–GIPC Interaction Inhibits Pancreatic Cancer Cell Growth Open
Detailed procedure for the synthesis of lipidated peptides.
View article: Effect of Integrated Nutrient Management on Quality, Yield, Nutrient Content and Uptake of Black Gram (Vigna mungo L.) in the South-eastern Plain of Rajasthan
Effect of Integrated Nutrient Management on Quality, Yield, Nutrient Content and Uptake of Black Gram (Vigna mungo L.) in the South-eastern Plain of Rajasthan Open
Background: To find out the suitable integrated nutrient management (INM) package for successful black gram production and to investigate the application of INM on growth, yield, quality and nutrient content of black gram (Vigna mungo L.).…
View article: Functional outcomes in the management of cervicothoracic junction tuberculosis
Functional outcomes in the management of cervicothoracic junction tuberculosis Open
Background: We analyzed the clinical and radiological parameters influencing functional outcomes and neurological recovery in patients with cervicothoracic junctional tuberculosis (TB). Methods: This was a retrospective analysis of 16 case…
View article: Isolated L5 nerve root injury without osseous disruption in a case of gunshot injury to the paediatric spine—A case report
Isolated L5 nerve root injury without osseous disruption in a case of gunshot injury to the paediatric spine—A case report Open
View article: Analysis of Functional Outcomes Following Surgical Management of Neglected Multiple Carpometacarpal Dislocations: A Series of 4 four Cases and Review of Literature
Analysis of Functional Outcomes Following Surgical Management of Neglected Multiple Carpometacarpal Dislocations: A Series of 4 four Cases and Review of Literature Open
Introduction: Dislocation of the carpometacarpal (CMC) joint is a rare injury that results following high-velocity trauma. Although there are a few anecdotal reports of isolated CMC joint dislocations, there is scarce literature concerning…
View article: COVID 19: Impact on Eye Health
COVID 19: Impact on Eye Health Open
COVID-19 virus causes mild to severe respiratory illness. People who are exposed to coronavirus may show symptoms anywhere from two to 14 days later. Those symptoms can include fever, cough and shortness of breath. Some people can develop …
View article: Integrin alphaVbeta1 inhibition ameliorates liver fibrosis in mice
Integrin alphaVbeta1 inhibition ameliorates liver fibrosis in mice Open
View article: AlphaVbeta6 inhibitor stabilizing the bent closed integrin conformation is effective in primary sclerosis cholangitis mouse model
AlphaVbeta6 inhibitor stabilizing the bent closed integrin conformation is effective in primary sclerosis cholangitis mouse model Open
View article: Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene
Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene Open
Here we report an in-silico approach for identification, characterization and validation of deleterious non-synonymous SNPs (nsSNPs) in the interleukin-8 gene using three steps. In first step, sequence homology-based genetic analysis of a …
View article: Abstract 1075: Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): Challenges and guidelines
Abstract 1075: Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): Challenges and guidelines Open
Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients. The Jackson Laboratory (JAX) PDX resource has over 450 models re…
View article: Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines
Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines Open
View article: Additional file 2: of Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines
Additional file 2: of Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines Open
Supplementary Tables S1, S13 and S14. (XLSX 94 kb)
View article: Bioinformatics workflows for genomic analysis of tumors from Patient Derived Xenografts (PDX): challenges and guidelines
Bioinformatics workflows for genomic analysis of tumors from Patient Derived Xenografts (PDX): challenges and guidelines Open
Bioinformatics workflows for analyzing genomic data obtained from xenografted tumor (e.g., human tumors engrafted in a mouse host) must address several challenges, including separating mouse and human sequence reads and accurate identifica…
View article: The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations
The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations Open
View article: To Evaluate the Efficacy of Ultrasound in Assessing Subglottic Tracheal Diameter for Endotracheal Intubation
To Evaluate the Efficacy of Ultrasound in Assessing Subglottic Tracheal Diameter for Endotracheal Intubation Open
View article: The Tandem Duplicator Phenotype is a prevalent genome-wide cancer configuration driven by distinct gene mutations
The Tandem Duplicator Phenotype is a prevalent genome-wide cancer configuration driven by distinct gene mutations Open
SUMMARY The tandem duplicator phenotype (TDP) is a genome-wide instability configuration primarily observed in breast, ovarian and endometrial carcinomas. Here, we stratify TDP tumors by classifying their tandem duplications (TDs) into thr…
View article: Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.
Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells. Open
VOLUME 291 (2016) PAGES 21984–22000 The University of Arkansas for Medical Sciences and Dr. Peter A. Crooks have financial interests in melampomagnolide B (MMB) and structurally related analogs discussed in this manuscript. These financial…
View article: Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells
Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells Open
Although multidrug approaches to cancer therapy are common, few strategies are based on rigorous scientific principles. Rather, drug combinations are largely dictated by empirical or clinical parameters. In the present study we developed a…
View article: Significance of duon mutations in cancer genomes
Significance of duon mutations in cancer genomes Open
Functional mutations in coding regions not only affect the structure and function of the protein products, but may also modulate their expression in some cases. This class of mutations, recently dubbed “duon mutations” due to their dual ro…
View article: The tandem duplicator phenotype as a distinct genomic configuration in cancer
The tandem duplicator phenotype as a distinct genomic configuration in cancer Open
Significance In this study, we provide the first detailed molecular characterization, to our knowledge, of a distinct cancer genomic configuration, the tandem duplicator phenotype (TDP), that is significantly enriched in the molecularly re…
View article: IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples
IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples Open
Objective Currently, there is a disconnect between finding a patient’s relevant molecular profile and predicting actionable therapeutics. Here we develop and implement the Integrating Molecular Profiles with Actionable Therapeutics (IMPACT…