Kabir Bhalla
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View article: Delivering a collaborative, discipline-specific, and equity, diversity, and inclusion-centered teaching assistant training program in the life sciences
Delivering a collaborative, discipline-specific, and equity, diversity, and inclusion-centered teaching assistant training program in the life sciences Open
A growing number of Canadian universities are implementing teaching assistant (TA) training programs designed to support graduate student teaching. At the University of British Columbia (UBC), the Life Sciences Institute (LSI) hosts one of…
View article: Polyphosphatases have a polyphosphate-independent influence on the virulence of <i>Cryptococcus neoformans</i>
Polyphosphatases have a polyphosphate-independent influence on the virulence of <i>Cryptococcus neoformans</i> Open
Cryptococcus neoformans, an invasive basidiomycete fungal pathogen, causes one of the most prevalent, life-threatening diseases in immunocompromised individuals and accounts for ~19% of AIDS-associated deaths. Therefore, understanding the …
View article: The HOPS and vCLAMP protein Vam6 connects polyphosphate with mitochondrial function and oxidative stress resistance in <i>Cryptococcus neoformans</i>
The HOPS and vCLAMP protein Vam6 connects polyphosphate with mitochondrial function and oxidative stress resistance in <i>Cryptococcus neoformans</i> Open
Cryptococcus neoformans is considered one of the most dangerous fungal threats to human health, and the World Health Organization recently ranked it in the critical priority group for perceived public health importance. Proliferation of C.…
View article: Phosphate availability conditions caspofungin tolerance, capsule attachment and titan cell formation in Cryptococcus neoformans
Phosphate availability conditions caspofungin tolerance, capsule attachment and titan cell formation in Cryptococcus neoformans Open
There is an urgent need for new antifungal drugs to treat invasive fungal diseases. Unfortunately, the echinocandin drugs that are fungicidal against other important fungal pathogens are ineffective against Cryptococcus neoformans , the ca…
View article: Loss of the putative Rab GTPase, Ypt7, impairs the virulence of Cryptococcus neoformans
Loss of the putative Rab GTPase, Ypt7, impairs the virulence of Cryptococcus neoformans Open
Small GTPases of the Rab family coordinate multiple membrane fusion and trafficking events in eukaryotes. In fungi, the Rab GTPase, Ypt7, plays a critical role in late endosomal trafficking, and is required for homotypic fusion events in v…
View article: Brilacidin, a novel antifungal agent against <i>Cryptococcus neoformans</i>
Brilacidin, a novel antifungal agent against <i>Cryptococcus neoformans</i> Open
Cryptococcus neoformans causes cryptococcosis, one of the most prevalent fungal diseases, generally characterized by meningitis. There is a limited and not very effective number of drugs available to combat this disease. In this manuscript…
View article: Polyphosphate mobilization influences the ability of<i>Cryptococcus neoformans</i>to cause disease in a murine model of cryptococcosis
Polyphosphate mobilization influences the ability of<i>Cryptococcus neoformans</i>to cause disease in a murine model of cryptococcosis Open
Cryptococcus neoformans , an invasive basidiomycete fungal pathogen, causes one of the most prevalent, life-threatening diseases in immunocompromised individuals and accounts for ∼15% of AIDS-associated deaths. A dire need for the developm…
View article: Brilacidin, a novel antifungal agent against<i>Cryptococcus neoformans</i>
Brilacidin, a novel antifungal agent against<i>Cryptococcus neoformans</i> Open
Cryptococcus neoformans causes cryptococcosis, one of the most prevalent fungal diseases, generally characterized by meningitis. There is a limited and not very effective number of drugs available to combat this disease. In this manuscript…
View article: Fungal-derived adsorption membrane to capture potentially toxic elements
Fungal-derived adsorption membrane to capture potentially toxic elements Open
The release of potentially toxic elements (PTEs) including zinc, copper, and cadmium poses a growing threat to global drinking water quality and accessibility, with marginalized communities often facing the greatest exposure and subsequent…
View article: Fungal-Derived Adsorption Membrane to Capture Potentially Toxic Elements
Fungal-Derived Adsorption Membrane to Capture Potentially Toxic Elements Open
View article: The phosphate language of fungi
The phosphate language of fungi Open
View article: Stringent response induced by amino acid starvation not involved in mediating broad spectrum antibiotic resistance in Escherichia coli
Stringent response induced by amino acid starvation not involved in mediating broad spectrum antibiotic resistance in Escherichia coli Open
Antibiotic resistance is a global threat to human welfare. The widespread use of antibiotics combined with a stagnation in the field of antibiotic development and discovery has exacerbated the problem of antibiotic resistance. It has there…