Kaichao Zhang
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View article: Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration (Adv. Sci. 34/2025)
Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration (Adv. Sci. 34/2025) Open
View article: Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration
Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration Open
Ferroptosis, a form of regulated cell death driven by iron accumulation and lipid peroxidation, is implicated in various diseases, but effective therapeutic strategies remain limited. Lysosomal impairments cause iron dysregulation and init…
View article: Golgi-restored vesicular replenishment retards bone aging and empowers aging bone regeneration
Golgi-restored vesicular replenishment retards bone aging and empowers aging bone regeneration Open
Healthy aging is a common goal for humanity and society, and one key to achieving it is the rejuvenation of senescent resident stem cells and empowerment of aging organ regeneration. However, the mechanistic understandings of stem cell sen…
View article: In-Situ Stress Prediction of Deep Coal Reservoir Considering Anisotropy: A Case Study of the North-Central Zijinshan Block, North China
In-Situ Stress Prediction of Deep Coal Reservoir Considering Anisotropy: A Case Study of the North-Central Zijinshan Block, North China Open
Hydraulic fracturing can significantly enhance coalbed methane production, with in-situ stress playing a crucial role in this process. Our study focuses on calculating in-situ stress in the deep 8+9# coal seam in the north-central Zijinsha…
View article: Introducing Strain Glass Transition into High-Entropy TiZrHfNiCuCo Alloys Exhibiting Elastocaloric Effect and Quasi-Linear Superelasticity
Introducing Strain Glass Transition into High-Entropy TiZrHfNiCuCo Alloys Exhibiting Elastocaloric Effect and Quasi-Linear Superelasticity Open
View article: Variation with Ni and Mn of the structural stability, magnetic properties and Kovar effect in Fe–Ni–Co based alloys
Variation with Ni and Mn of the structural stability, magnetic properties and Kovar effect in Fe–Ni–Co based alloys Open
As a typical commercial Kovar alloy, the Fe–Ni–Co based alloy with nominal ∼29 wt% Ni, ∼17 wt% Co, and minor Mn and Si has found abroad applications in electronic and optoelectronics fields because of its analogous thermal expansion coeffi…
View article: Beige adipose tissue-derived extracellular vesicles: a potent metabolic regulator and a novel remedy for nonalcoholic fatty liver disease
Beige adipose tissue-derived extracellular vesicles: a potent metabolic regulator and a novel remedy for nonalcoholic fatty liver disease Open
Adipose tissue (AT) is an essential metabolic and endocrine organ, which are categorized into the white adipose tissue (WAT) and the brown adipose tissue (BAT), as well as the beige adipose tissue (BeAT) that derives from WAT browning. Not…
View article: Development-Inspired Biomimetic Cell-Niche Co-Aggregates Safeguard Tooth Stem Cell-Based Functional Tissue Regeneration
Development-Inspired Biomimetic Cell-Niche Co-Aggregates Safeguard Tooth Stem Cell-Based Functional Tissue Regeneration Open
View article: Mesenchymal Stem Cell Aggregation‐Released Extracellular Vesicles Induce CD31<sup>+</sup>EMCN<sup>+</sup> Vessels in Skin Regeneration and Improve Diabetic Wound Healing (Adv. Healthcare Mater. 20/2023)
Mesenchymal Stem Cell Aggregation‐Released Extracellular Vesicles Induce CD31<sup>+</sup>EMCN<sup>+</sup> Vessels in Skin Regeneration and Improve Diabetic Wound Healing (Adv. Healthcare Mater. 20/2023) Open
Extracellular Vesicles In article number 2300019, Bing-Dong Sui, Yan Jin, Fang Jin, and co-workers discover mesenchymal stem cell aggregates secrete angiogenic extracellular vesicles, which exert high efficacy in boosting CD31+EMCN+ vessel…
View article: Failure modeling and reliability analysis for motion mechanism with clearance joints under plastic deformation and wear
Failure modeling and reliability analysis for motion mechanism with clearance joints under plastic deformation and wear Open
The performance failure and reliability of motion mechanism has a significant effect on industry reliability, operation safety and production economy. Motion precise is one of the typical performance indicators especially for motion mechan…
View article: Competing Failure Modeling for Systems under Classified Random Shocks and Degradation
Competing Failure Modeling for Systems under Classified Random Shocks and Degradation Open
A new model is presented to analyze reliability for systems subjected to competing risks of a typical degradation process and external random shocks. The external random shocks may cause hard failure and instantaneous increases in the degr…
View article: Targeted inhibition of osteoclastogenesis reveals the pathogenesis and therapeutics of bone loss under sympathetic neurostress
Targeted inhibition of osteoclastogenesis reveals the pathogenesis and therapeutics of bone loss under sympathetic neurostress Open
Sympathetic cues via the adrenergic signaling critically regulate bone homeostasis and contribute to neurostress-induced bone loss, but the mechanisms and therapeutics remain incompletely elucidated. Here, we reveal an osteoclastogenesis-c…
View article: Elastic Modulus Anomaly in a Fe-Mn-Cr-C Cryogenic Steel
Elastic Modulus Anomaly in a Fe-Mn-Cr-C Cryogenic Steel Open
View article: Strain Glass Transition in a Metastable β Ti-Nb-O Alloy with High Oxygen Content
Strain Glass Transition in a Metastable β Ti-Nb-O Alloy with High Oxygen Content Open
View article: Towards the selectivity distinction of phenol hydrogenation on noble metal catalysts
Towards the selectivity distinction of phenol hydrogenation on noble metal catalysts Open
Selective hydrogenation of phenol to cyclohexanone is intriguing in chemical industry. Though a few catalysts with promising performances have been developed in recent years, the basic principle for catalyst design is still missing owing t…
View article: Structural stability，microstructure and mechanical behavior of Ti-10V-2Fe-3Al alloy
Structural stability，microstructure and mechanical behavior of Ti-10V-2Fe-3Al alloy Open
In the present study, Ti-10V-2Fe-3Al (Ti-1023) alloy was prepared by vacuum consumable melting and forging technique. The structural stability, microstructural evolution and mechanical behavior of the alloy were systematically investigated…
View article: Microstructural evolution in the surface of Ti–10V–2Fe–3Al alloy by solution treatments
Microstructural evolution in the surface of Ti–10V–2Fe–3Al alloy by solution treatments Open
By solution treatments in vacuum and in air, the surface region of Ti–10V–2Fe–3Al exhibits different microstructures from the interior region of the alloy. When solution treated in vacuum, the microstructure of the specimen is composed of …