Kailong Li
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View article: Advancements in photoelectrode surface, electrolyte, and integrated configurations for solar redox flow batteries – A mini review
Advancements in photoelectrode surface, electrolyte, and integrated configurations for solar redox flow batteries – A mini review Open
Under the background of the increasing contradiction between global energy supply and demand as well as large-scale application of renewable energy, as an application of flow battery technology in solar energy storage, solar redox flow bat…
View article: Sustainable Wall Design in Sunken Solar Greenhouses: Integrating Energy Balance Analysis for Thermal Performance Maximization
Sustainable Wall Design in Sunken Solar Greenhouses: Integrating Energy Balance Analysis for Thermal Performance Maximization Open
View article: βAR-mTOR-lipin1 pathway mediates PKA-RIIβ deficiency-induced adipose browning
βAR-mTOR-lipin1 pathway mediates PKA-RIIβ deficiency-induced adipose browning Open
Background: Enhancing white adipose tissue (WAT) browning combats obesity. The RIIβ subunit of cAMP-dependent protein kinase (PKA) is primarily expressed in the brain and adipose tissue. Deletion of the hypothalamic RIIβ gene centra…
View article: Long-term outcomes of endovascular treatment of acute lower limb deep-vein thrombosis combined with May–Thurner syndrome: A single-center retrospective cohort study
Long-term outcomes of endovascular treatment of acute lower limb deep-vein thrombosis combined with May–Thurner syndrome: A single-center retrospective cohort study Open
OBJECTIVE: May–Thurner syndrome (MTS) is a common cause of lower-extremity deep venous thrombosis (DVT). Stenting is effective in the treatment of MTS; however, there are still complications that may affect the patency of the stent. In add…
View article: Table S3 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S3 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S3 shows sequences of primers and shRNAs
View article: Table S1 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S1 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S1 shows the list of genomic datasets
View article: Table S2 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S2 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S2 shows differentially expressed genes by RNA-seq
View article: Table S3 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S3 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S3 shows sequences of primers and shRNAs
View article: Supplementary Figures and Legends from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Supplementary Figures and Legends from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Supplementary Figures and Legends combined file contains 14 supplementary figures
View article: Table S1 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S1 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S1 shows the list of genomic datasets
View article: Supplementary Figures and Legends from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Supplementary Figures and Legends from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Supplementary Figures and Legends combined file contains 14 supplementary figures
View article: Table S4 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S4 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S4 shows key reagents and resources
View article: Table S2 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S2 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S2 shows differentially expressed genes by RNA-seq
View article: Data from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Data from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Epigenetic gene regulation and metabolism are highly intertwined, yet little is known about whether altered epigenetics influence cellular metabolism during cancer progression. Here, we show that EZH2 and NRASG12D mutations coop…
View article: Table S5 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S5 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S5 shows transitions and parameters used for LC-MS
View article: Table S5 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S5 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S5 shows transitions and parameters used for LC-MS
View article: Data from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Data from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Epigenetic gene regulation and metabolism are highly intertwined, yet little is known about whether altered epigenetics influence cellular metabolism during cancer progression. Here, we show that EZH2 and NRASG12D mutations coop…
View article: Table S4 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S4 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation Open
Table S4 shows key reagents and resources
View article: Annotation and evaluation of base editing outcomes in multiple cell types using CRISPRbase
Annotation and evaluation of base editing outcomes in multiple cell types using CRISPRbase Open
CRISPR-Cas base editing (BE) system is a powerful tool to expand the scope and efficiency of genome editing with single-nucleotide resolution. The editing efficiency, product purity, and off-target effect differ among various BE systems. H…
View article: Landslide Susceptibility Prediction Considering Neighborhood Characteristics of Landslide Spatial Datasets and Hydrological Slope Units Using Remote Sensing and GIS Technologies
Landslide Susceptibility Prediction Considering Neighborhood Characteristics of Landslide Spatial Datasets and Hydrological Slope Units Using Remote Sensing and GIS Technologies Open
Landslides are affected not only by their own environmental factors, but also by the neighborhood environmental factors and the landslide clustering effect, which are represented as the neighborhood characteristics of modelling spatial dat…
View article: Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19
Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19 Open
View article: Surgical treatment of traumatic arteriovenous fistula after failed endovascular treatment
Surgical treatment of traumatic arteriovenous fistula after failed endovascular treatment Open
Endovascular interventional therapy is the first choice for the treatment of the traumatic arteriovenous fistula (AVF) because of its small trauma, fast recovery, exact effect, and low incidence of complications. However, surgery is still …
View article: Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation
Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation Open
View article: The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer Open
View article: Risk factors and prognosis for COVID-19-induced acute kidney injury: a meta-analysis
Risk factors and prognosis for COVID-19-induced acute kidney injury: a meta-analysis Open
Objective To analyse the incidence, risk factors and impact of acute kidney injury (AKI) on the prognosis of patients with COVID-19. Design Meta-analysis. Data sources PubMed, Embase, CNKI and MedRxiv of Systematic Reviews from 1 January 2…
View article: Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer
Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer Open
MYC stimulates both metabolism and protein synthesis, but how cells coordinate these complementary programs is unknown. Previous work reported that, in a subset of small-cell lung cancer (SCLC) cell lines, MYC activates guanosine triphosph…
View article: TRAF6 Promotes Gastric Cancer Cell Self-Renewal, Proliferation, and Migration
TRAF6 Promotes Gastric Cancer Cell Self-Renewal, Proliferation, and Migration Open
Gastric cancer is the third most common type of tumor associated with death. TRAF6 belongs to the tumor necrosis factor receptor-associated factor family and has been demonstrated to be involved in tumor progression in various cancers. How…
View article: The hexosamine biosynthesis pathway is a targetable liability in lung cancers with concurrent KRAS and LKB1 mutations
The hexosamine biosynthesis pathway is a targetable liability in lung cancers with concurrent KRAS and LKB1 mutations Open
In non–small cell lung cancer (NSCLC), concurrent mutations in the oncogene KRAS and the tumor suppressor STK11 encoding the kinase LKB1 result in aggressive tumors prone to metastasis but with liabilities arising from reprogrammed metabol…
View article: Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies
Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies Open
Mutations in protein-coding genes are well established as the basis for human cancer, yet how alterations within noncoding genome, a substantial fraction of which contain cis-regulatory elements (CRE), contribute to cancer pathophysiology …
View article: Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing Open