Kailu Zhang
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View article: Prognostic implications of biventricular strain and ischemic-pattern fibrosis in non-ischemic dilated cardiomyopathy with type 2 diabetes mellitus: a cardiac MRI cohort study
Prognostic implications of biventricular strain and ischemic-pattern fibrosis in non-ischemic dilated cardiomyopathy with type 2 diabetes mellitus: a cardiac MRI cohort study Open
T2DM adversely affects biventricular myocardial strain, LGE mass ratio, and ischemic LGE prevalence in non-ischemic DCM patients. Combining NT-proBNP, HbA1c, LVGLS, and ischemic LGE prevalence may serve as effective markers for predicting …
View article: Advances in the Biosynthetic Regulation and Functional Mechanisms of Glycine Betaine for Enhancing Plant Stress Resilience
Advances in the Biosynthetic Regulation and Functional Mechanisms of Glycine Betaine for Enhancing Plant Stress Resilience Open
Plants are frequently exposed to a range of abiotic stresses, including drought, salinity, extreme temperatures, and heavy metals, that severely impair their growth and productivity. Among the adaptive mechanisms that plants have evolved, …
View article: Change of bone mineral density as a prognostic marker in small cell lung cancer treated with immune checkpoint inhibitors: a multicenter retrospective study
Change of bone mineral density as a prognostic marker in small cell lung cancer treated with immune checkpoint inhibitors: a multicenter retrospective study Open
Lower ΔBMD is correlated with poorer clinical outcomes in SCLC patients undergoing treatment with ICIs.
View article: Prognostic impact of extracellular volume fraction derived from equilibrium contrast-enhanced CT in HCC patients receiving immune checkpoint inhibitors
Prognostic impact of extracellular volume fraction derived from equilibrium contrast-enhanced CT in HCC patients receiving immune checkpoint inhibitors Open
View article: Optimization of solid fermentation conditions of organic fertilizer from fish and tobacco wastes and its effects on crop production and soil quality 
Optimization of solid fermentation conditions of organic fertilizer from fish and tobacco wastes and its effects on crop production and soil quality Open
Microbial fermentation fertilizer from agricultural organic wastes represents a novel, environmentally friendly, and safe type of bio-organic fertilizer. However, the development and application of solid fermentation using fish by-products…
View article: CT-based delta-radiomics for predicting pathological response to neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma: a multicenter study
CT-based delta-radiomics for predicting pathological response to neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma: a multicenter study Open
View article: SWATH-MS based proteomics reveals the role of photosynthesis related proteins and secondary metabolic pathways in the colored leaves of sweet olive (Osmanthus fragrans)
SWATH-MS based proteomics reveals the role of photosynthesis related proteins and secondary metabolic pathways in the colored leaves of sweet olive (Osmanthus fragrans) Open
Colored leaves, a notable horticultural trait, have high research and ornamental value. The evergreen sweet olive (Osmanthus fragrans), one of the top ten traditional flowers in China, has been cultivated for more than two thousand years. …
View article: Predictive value of delta-radiomic features for prognosis of advanced non-small cell lung cancer patients undergoing immune checkpoint inhibitor therapy
Predictive value of delta-radiomic features for prognosis of advanced non-small cell lung cancer patients undergoing immune checkpoint inhibitor therapy Open
The delta-radiomics model showed a good performance in predicting therapeutic outcomes in advanced NSCLC patients undergoing ICI therapy. It provides a higher predictive value than clinical and the pre-treatment radiomics models.
View article: A validated model to predict spread through air space in lung adenocarcinoma
A validated model to predict spread through air space in lung adenocarcinoma Open
The outcome of STAS-positive patients was worse. The nomogram incorporating the identified CT features could be applied to facilitate individualized preoperative prediction of STAS and selection of rational therapy.
View article: Biomechanical characteristics of Sanders type II and III calcaneal fractures fixed by open reduction and internal fixation and percutaneous minimally invasive fixation
Biomechanical characteristics of Sanders type II and III calcaneal fractures fixed by open reduction and internal fixation and percutaneous minimally invasive fixation Open
View article: Utility and predictive value of the CRAFITY score in advanced hepatocellular carcinoma treated with transarterial chemoembolization plus tyrosine kinase inhibitors and PD-1 inhibitor
Utility and predictive value of the CRAFITY score in advanced hepatocellular carcinoma treated with transarterial chemoembolization plus tyrosine kinase inhibitors and PD-1 inhibitor Open
View article: Biodegradation of phthalic acid esters (PAEs) by <i>Janthinobacterium</i> sp. strain E1 under stress conditions
Biodegradation of phthalic acid esters (PAEs) by <i>Janthinobacterium</i> sp. strain E1 under stress conditions Open
Phthalates esters (PAEs) are a kind of polymeric material additives widely been added into plastics to improve products' flexibility. It can easily cause environmental pollution which are hazards to public health. In this study, we isolate…
View article: Prognostic Impact of Equilibrium Contrast-Enhanced Ct in Hcc Patients Receiving Immune Checkpoint Inhibitors: Extracellular Volume Fraction
Prognostic Impact of Equilibrium Contrast-Enhanced Ct in Hcc Patients Receiving Immune Checkpoint Inhibitors: Extracellular Volume Fraction Open
View article: Serum prolactin and gonadal hormones in hemodialysis women: a meta-analysis
Serum prolactin and gonadal hormones in hemodialysis women: a meta-analysis Open
Background A meta-analysis followed by PRISMA 2020 statement was performed aiming to present a whole prolactin and sex hormone profile in hemodialysis women. Methods Literatures were searched in PubMed, Cochrane library, Embase, and Web of…
View article: Multimodality imaging assessment of primary pericardial rhabdomyosarcoma: a case report
Multimodality imaging assessment of primary pericardial rhabdomyosarcoma: a case report Open
Primary pericardial sarcomas are rare and lethal diseases. To date, only a few cases of primary pericardial sarcomas, such as rhabdomyosarcoma (RMS), have been reported. Since the unusual location of RMS in the pericardium makes it challen…
View article: Dual-energy CT-based radiomics for predicting invasiveness of lung adenocarcinoma appearing as ground-glass nodules
Dual-energy CT-based radiomics for predicting invasiveness of lung adenocarcinoma appearing as ground-glass nodules Open
Objectives To explore the value of radiomics based on Dual-energy CT (DECT) for discriminating preinvasive or MIA from IA appearing as GGNs before surgery. Methods The retrospective study included 92 patients with lung adenocarcinoma compr…
View article: Asymmetric Measurement-Device-Independent Quantum Key Distribution through Advantage Distillation
Asymmetric Measurement-Device-Independent Quantum Key Distribution through Advantage Distillation Open
Measurement-device-independent quantum key distribution (MDI-QKD) completely closes the security loopholes caused by the imperfection of devices at the detection terminal. Commonly, a symmetric MDI-QKD model is widely used in simulations a…
View article: Micro‐histology combined with cytology improves the diagnostic accuracy of endometrial lesions
Micro‐histology combined with cytology improves the diagnostic accuracy of endometrial lesions Open
Background In the study, we aimed to evaluate the ability of micro‐histology combined with cytology to improve the quality of slides and diagnose endometrial lesions. Methods Endometrial specimens were collected from Li Brushes. Every spec…
View article: Value of radiomics in differentiating synchronous double primary lung adenocarcinomas from intrapulmonary metastasis
Value of radiomics in differentiating synchronous double primary lung adenocarcinomas from intrapulmonary metastasis Open
The differences of radiomics features showed excellent diagnostic performance for preoperative differentiation between synchronous double primary lung adenocarcinoma from interpulmonary metastasis, superior to the clinical model and decisi…
View article: CD7 protein plays a crucial role in T cell infiltration in tumors
CD7 protein plays a crucial role in T cell infiltration in tumors Open
View article: Prognostic Factors for Survival in Multiple Primary Lung Adenocarcinomas: A Retrospective Analysis of 283 Patients
Prognostic Factors for Survival in Multiple Primary Lung Adenocarcinomas: A Retrospective Analysis of 283 Patients Open
Purpose: In recent years, a rising number of multiple primary lung cancers have been detected with the advancement of imaging technology. No detailed study has assessed the prognosis of multiple primary lung adenocarcinomas based on comput…
View article: Left atrioventricular groove pseudo-aneurysm demonstrated by multimodality imaging
Left atrioventricular groove pseudo-aneurysm demonstrated by multimodality imaging Open
A 41-year-old male was admitted because routine chest computed tomography (CT) examination revealed possible pericardial mass. The patient was asymptomatic and had history of cured tuberculosis. He denied risk factors for coronary artery d…
View article: Multi-Flexible Body Dynamics Modeling and Experimental Study of the Patient Rehabilitation Transfer Device
Multi-Flexible Body Dynamics Modeling and Experimental Study of the Patient Rehabilitation Transfer Device Open
Objectives. The patient rehabilitation transfer device is a typical personnel transfer equipment, which is mainly composed of outriggers, support arm, lifting arms, hooks, handrails, hydraulic cylinders, and other components. The existing …
View article: Identification of miRNAs and Target Genes at Key Stages of Sexual Differentiation in Androdioecious Osmanthus fragrans
Identification of miRNAs and Target Genes at Key Stages of Sexual Differentiation in Androdioecious Osmanthus fragrans Open
Androdioecy is the crucial transition state in the evolutionary direction of hermaphroditism to dioecy, however, the molecular mechanisms underlying the formation of this sex system remain unclear. While popular in China for its ornamental…
View article: RPRM deletion preserves hematopoietic regeneration by promoting EGFR‐dependent DNA repair and hematopoietic stem cell proliferation post ionizing radiation
RPRM deletion preserves hematopoietic regeneration by promoting EGFR‐dependent DNA repair and hematopoietic stem cell proliferation post ionizing radiation Open
Reprimo (RPRM), a target gene of p53, is a known tumor suppressor. DNA damage induces RPRM, which triggers p53‐dependent G2 arrest by inhibiting cyclin B1/Cdc2 complex activation and promotes DNA damage‐induced apoptosis. RPRM negatively r…
View article: The Value of CT-Based Radiomics for Predicting Spread Through Air Spaces in Stage IA Lung Adenocarcinoma
The Value of CT-Based Radiomics for Predicting Spread Through Air Spaces in Stage IA Lung Adenocarcinoma Open
Objectives Spread through air spaces (STAS), a new invasive pattern in lung adenocarcinoma (LUAD), is a risk factor for poor outcome in early-stage LUAD. This study aimed to develop and validate a CT-based radiomics model for predicting ST…
View article: Extremely high serum CA19-9 level along with elevated D-dimer in assisting detection of ruptured ovarian endometriosis
Extremely high serum CA19-9 level along with elevated D-dimer in assisting detection of ruptured ovarian endometriosis Open
The combination of CA19-9 and D-D can be chosen as an effective and economical indicators to identify patients with spontaneously ruptured OE in pre-operation assessment. However, from the perspective of differential diagnosis, the combina…
View article: Hypermethylated CDO1 and ZNF454 in Cytological Specimens as Screening Biomarkers for Endometrial Cancer
Hypermethylated CDO1 and ZNF454 in Cytological Specimens as Screening Biomarkers for Endometrial Cancer Open
We aimed to estimate the diagnostic value of DNA methylation levels in cytological samples of endometrial cancer (EC) and atypical hyperplasia (AH). Two hypermethylated genes, namely, cysteine dioxygenase type 1 ( CDO1 ) and zinc finger pr…
View article: Blood Bacterial 16S rRNA Gene Alterations in Women With Polycystic Ovary Syndrome
Blood Bacterial 16S rRNA Gene Alterations in Women With Polycystic Ovary Syndrome Open
Background Evidence proved the association between gut microbiome dysbiosis and polycystic ovary syndrome (PCOS) in metabolic disorder, decreased fertility, and hyperandrogenism. However, alterations in blood microbiome of PCOS remained un…
View article: Nanobody-based anti-CD22-chimeric antigen receptor T cell immunotherapy exhibits improved remission against B-cell acute lymphoblastic leukemia
Nanobody-based anti-CD22-chimeric antigen receptor T cell immunotherapy exhibits improved remission against B-cell acute lymphoblastic leukemia Open
Chimeric antigen receptor (CAR) T-cell immunotherapies targeting CD19 can achieve impressive clinical remission rates in the treatment of B-cell non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia. However, relapse after CD19-CAR …