Jiawen Li
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View article: Impact of Glucose Metabolism Status on the Association between Apolipoprotein A-I and Ischemic Risk in Patients with Coronary Artery Disease: A Large-Sample Cohort Study
Impact of Glucose Metabolism Status on the Association between Apolipoprotein A-I and Ischemic Risk in Patients with Coronary Artery Disease: A Large-Sample Cohort Study Open
This large-scale, 5-year follow-up study is the first to demonstrate that lower ApoA-I levels are associated with increased MACCE risk in CAD patients with DM, highlighting the potential value of ApoA-I in risk stratification and as a ther…
View article: Combined and progressive effect of frailty and sarcopenia on the risk of cardiovascular disease in middle-aged and older adults
Combined and progressive effect of frailty and sarcopenia on the risk of cardiovascular disease in middle-aged and older adults Open
The study indicated there was a combined and progressive effect of frailty and sarcopenia on CVD. These findings highlighted the importance of identifying and improving sarcopenia and frailty.
View article: Role of transforming growth factorβ in neurovascular unit during cerebral small vessel disease
Role of transforming growth factorβ in neurovascular unit during cerebral small vessel disease Open
View article: Association of Remnant Cholesterol with Platelet Reactivity in Coronary Artery Disease Patients Receiving PCI
Association of Remnant Cholesterol with Platelet Reactivity in Coronary Artery Disease Patients Receiving PCI Open
Background: Remnant cholesterol (RC) has received increasing attention and shown to be associated with bleeding and ischemic events in clinical research; however, the mechanisms remain incompletely understood. Aim: To investigate the relat…
View article: Synergistic interaction and cumulative effect between frailty and triglyceride-glucose index exacerbate cardiovascular disease burden in middle-aged and older adults
Synergistic interaction and cumulative effect between frailty and triglyceride-glucose index exacerbate cardiovascular disease burden in middle-aged and older adults Open
View article: Update of machine learning for ultrasound diagnosis of metabolic dysfunction-associated steatotic liver disease: a bright future for deep learning
Update of machine learning for ultrasound diagnosis of metabolic dysfunction-associated steatotic liver disease: a bright future for deep learning Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common liver disease and the burden is increasing around the world. Ultrasound diagnosis of MASLD is the preferred method due to its convenience, absence of radia…
View article: A Retrospective Cohort Study: Predictive Value of Biomarkers for Mortality in Bloodstream Infection Patients
A Retrospective Cohort Study: Predictive Value of Biomarkers for Mortality in Bloodstream Infection Patients Open
Objective To investigate the predictive value of procalcitonin (PCT), uric acid, platelet count, and neutrophil-to-lymphocyte ratio (NLR) for mortality risk in blood culture-positive sepsis patients. Methods A retrospective analysis was co…
View article: The relationship between ABO blood types and clopidogrel-related low on-treatment platelet reactivity in patients with coronary artery diseases and type 2 diabetes mellitus: a secondary analysis of a prospective cohort study
The relationship between ABO blood types and clopidogrel-related low on-treatment platelet reactivity in patients with coronary artery diseases and type 2 diabetes mellitus: a secondary analysis of a prospective cohort study Open
This study reported that in patients with CAD and T2DM, blood type O was independently associated with higher odds of LTPR, indicating a greater likelihood of bleeding, while blood type A was independently related to lower odds of LTPR, su…
View article: Mechanical and Electromagnetic Interference Shielding Properties of Structurally Reinforced Aluminum Foam
Mechanical and Electromagnetic Interference Shielding Properties of Structurally Reinforced Aluminum Foam Open
View article: LDL‐C and hs‐CRP Jointly Modify the Effect of Lp(a) on 5‐Year Death in Patients With Percutaneous Coronary Intervention
LDL‐C and hs‐CRP Jointly Modify the Effect of Lp(a) on 5‐Year Death in Patients With Percutaneous Coronary Intervention Open
Background Recent studies have suggested that adverse events associated with lipoprotein(a) [Lp(a)] might be modified by low‐density lipoprotein cholesterol (LDL‐C) or high‐sensitivity C‐reactive protein (hs‐CRP) levels, but whether LDL‐C …
View article: Prognostic value of Glasgow Prognostic Score and its modified scores on 5-year outcome in patients with coronary heart disease undergoing percutaneous coronary intervention
Prognostic value of Glasgow Prognostic Score and its modified scores on 5-year outcome in patients with coronary heart disease undergoing percutaneous coronary intervention Open
In patients with CHD who underwent PCI, GPS, mGPS, and hs-mGPS demonstrated significant long-term predictive values for all-cause death. Our parameter-adjusted score, the CHD-hs-mGPS, is applicable to a broad population and moderately enha…
View article: The establishment and severity assessment of ultrasound-guided prenatal bronchopulmonary dysplasia model in rat
The establishment and severity assessment of ultrasound-guided prenatal bronchopulmonary dysplasia model in rat Open
View article: A horizontal and perpendicular interlaminar approach for intrathecal nusinersen injection in patients with spinal muscular atrophy and scoliosis: an observational study
A horizontal and perpendicular interlaminar approach for intrathecal nusinersen injection in patients with spinal muscular atrophy and scoliosis: an observational study Open
Background Lumbar puncture is challenging for patients with scoliosis. Previous ultrasound-assisted techniques for lumbar puncture used the angle of the probe as the needle trajectory; however, reproducing the angle is difficult and increa…
View article: Long-Term Outcomes of Sex Differences in Three-Vessel Coronary Disease with Different Treatment Strategies: A Large Cohort Study
Long-Term Outcomes of Sex Differences in Three-Vessel Coronary Disease with Different Treatment Strategies: A Large Cohort Study Open
Aim: The information assessing sex differences in outcomes of patients with three-vessel coronary disease (TVD) after different treatment strategies is sparse. This study aimed to investigate long-term outcomes of TVD among women compared …
View article: Reproducibility of semi-quantitative assessment of aortic valve calcification and valve motion on echocardiography: a small-scale study
Reproducibility of semi-quantitative assessment of aortic valve calcification and valve motion on echocardiography: a small-scale study Open
View article: Associations of HDL-C and ApoA-I with Mortality Risk in PCI Patients Across Different hsCRP Levels
Associations of HDL-C and ApoA-I with Mortality Risk in PCI Patients Across Different hsCRP Levels Open
In PCI patients with hsCRP ≥ 2 mg/L. both low and high HDL-C levels correlated with higher cardiac mortality risk (U-shaped), while only low ApoA-I levels were linked to elevated risk (L-shaped). However, in patients with hsCRP < 2 mg/L, n…
View article: Main focus of parents of children with attention deficit hyperactivity disorder and the effectiveness of early clinical screening
Main focus of parents of children with attention deficit hyperactivity disorder and the effectiveness of early clinical screening Open
BACKGROUND Attention deficit hyperactivity disorder (ADHD) is a common mental and behavioral disorder among children. AIM To explore the focus of attention deficit hyperactivity disorder parents and the effectiveness of early clinical scre…
View article: Transperineal ultrasound measurement of the levator plate angle and anorectal angle is a useful method for evaluating uterine prolapse : a prospective cohort study
Transperineal ultrasound measurement of the levator plate angle and anorectal angle is a useful method for evaluating uterine prolapse : a prospective cohort study Open
Background Confirming the patient's cervical position using transperineal ultrasound is not an easy task. This study aimed to employ transperineal ultrasound to measure the levator plate angle (LPA) and anorectal angle (ARA) in patients wi…
View article: Prospective clinical study of the efficacy and safety of different doses of PEG recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) for preventing leukopenia/neutropenia caused by concurrent chemoradiotherapy for cervical cancer
Prospective clinical study of the efficacy and safety of different doses of PEG recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) for preventing leukopenia/neutropenia caused by concurrent chemoradiotherapy for cervical cancer Open
Objective The efficacy and safety of different doses of PEG recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) in the prevention of leukopenia/neutropenia during concurrent chemoradiotherapy for cervical cancer were inve…
View article: The 11β-hydroxysteroid dehydrogenase type 1 inhibitor SPI-62 prevents morbidity in a mouse model of Cushing’s syndrome
The 11β-hydroxysteroid dehydrogenase type 1 inhibitor SPI-62 prevents morbidity in a mouse model of Cushing’s syndrome Open
11β-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibitors represent a potential therapeutic approach for patients with Cushing’s syndrome, autonomous cortisol secretion (ACS), or iatrogenic glucocorticoid (GC) excess. We assessed whether …
View article: Inflammation modifies the platelet reactivity among thrombocytopenia patients undergoing percutaneous coronary intervention
Inflammation modifies the platelet reactivity among thrombocytopenia patients undergoing percutaneous coronary intervention Open
Percutaneous coronary intervention (PCI) patients combined with thrombocytopenia (TP) are usually considered to be at low ischemic risk, receiving less proper antiplatelet therapy. However, recent studies reported a paradoxical phenomenon …
View article: DNA methylation of skeletal muscle function‐related secretary factors identifies FGF2 as a potential biomarker for sarcopenia
DNA methylation of skeletal muscle function‐related secretary factors identifies FGF2 as a potential biomarker for sarcopenia Open
Background Sarcopenia is characterized by progressive loss of muscle mass and function due to aging. DNA methylation has been identified to play important roles in the dysfunction of skeletal muscle. The aim of our present study was to exp…
View article: FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy Open
View article: Association of NPC1L1 and HMGCR gene polymorphisms with coronary artery calcification in patients with premature triple-vessel coronary disease
Association of NPC1L1 and HMGCR gene polymorphisms with coronary artery calcification in patients with premature triple-vessel coronary disease Open
Background Coronary artery calcification (CAC) is a highly specific marker of atherosclerosis. Niemann-Pick C1-like 1 (NPC1L1) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are the therapeutic targets of ezetimibe and statins…
View article: Deciphering m<sup>6</sup>A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy
Deciphering m<sup>6</sup>A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy Open
Rationale: Device implantation frequently triggers cardiac remodeling and fibrosis, with monocyte-driven inflammatory responses precipitating arrhythmias. This study investigates the role of m6A modification enzymes METTL…
View article: Elevated High-Sensitivity C-Reactive Protein Level Enhances the Impact of Lipoprotein(a) on Platelet Reactivity in PCI Patients Treated with Clopidogrel
Elevated High-Sensitivity C-Reactive Protein Level Enhances the Impact of Lipoprotein(a) on Platelet Reactivity in PCI Patients Treated with Clopidogrel Open
Background Recently, the effect of Lipoprotein(a) [Lp(a)] on thrombogenesis has aroused great interest, while inflammation has been reported to modify the Lp(a)-associated risks through an unidentified mechanism. Purpose This study aimed t…
View article: Ultrasound-assisted lumbar puncture with a horizontal and perpendicular paramedian approach based on positioning in patients with abnormal spinal anatomy: a case report and technical description
Ultrasound-assisted lumbar puncture with a horizontal and perpendicular paramedian approach based on positioning in patients with abnormal spinal anatomy: a case report and technical description Open
View article: Correlation between Colour Traits and Intrinsic Quality of Dalbergiae Odoriferae Lignum
Correlation between Colour Traits and Intrinsic Quality of Dalbergiae Odoriferae Lignum Open
Dalbergia odorifera T. Chen is traditionally referred to as „Dalbergiae Odoriferae Lignum” in traditional Chinese medicine. Its quality is typically assessed subjectively based on colour and texture observations and lacks a universal gradi…
View article: One-year clinical outcomes of bivalirudin versus unfractionated heparin in patients with type 2 diabetes undergoing elective percutaneous coronary intervention
One-year clinical outcomes of bivalirudin versus unfractionated heparin in patients with type 2 diabetes undergoing elective percutaneous coronary intervention Open
Although diabetes is considered a high-risk factor for poor prognosis, compared with UFH (with or without GPI), bivalirudin did not increase the risk of MACCE and even decreased the risk of MI in patients with T2D undergoing elective PCI, …
View article: Remnant cholesterol but not LDL cholesterol is associated with 5-year bleeding following percutaneous coronary intervention
Remnant cholesterol but not LDL cholesterol is associated with 5-year bleeding following percutaneous coronary intervention Open