Kaining Zhang
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View article: A novel supramolecular nanodrugs for improving the cognitive function of schizophrenia by protecting active lactone of arecoline
A novel supramolecular nanodrugs for improving the cognitive function of schizophrenia by protecting active lactone of arecoline Open
Over 30 % of patients with schizophrenia experience treatment resistance and severe side effects. The limited efficacy of antipsychotic therapies poses a challenge, partly due to the blood-brain barrier (BBB) and the non-selective targetin…
View article: Pain Characteristics of the Posterior Longitudinal Ligament in Percutaneous Endoscopic Lumbar Discectomy and its Significance: A Retrospective Study
Pain Characteristics of the Posterior Longitudinal Ligament in Percutaneous Endoscopic Lumbar Discectomy and its Significance: A Retrospective Study Open
Differences in pain distribution and intensity were observed when the PLL was incited at different spinal levels during PELD surgery.
View article: Repeated PVP with pedicle-anchoring technique for cement displacement in Kümmell disease
Repeated PVP with pedicle-anchoring technique for cement displacement in Kümmell disease Open
View article: Ankylosing spondylitis complicated with traumatic thoracic fracture dislocation with old spinal cord injury
Ankylosing spondylitis complicated with traumatic thoracic fracture dislocation with old spinal cord injury Open
View article: Successful therapy by WBRT with concurrent intrathecal MTX for isolated leptomeningeal metastasis in ER+ HER2− breast cancer: case report
Successful therapy by WBRT with concurrent intrathecal MTX for isolated leptomeningeal metastasis in ER+ HER2− breast cancer: case report Open
Background: Leptomeningeal metastasis(LM) is a relatively rare but devastating manifestation of breast cancer, with an incidence rate of approximately 5%, half of these patients suffer from simultaneous brain metastasis. LM in breast cance…
View article: Congenital Lumbosacral Malformations with Low‐Grade Neuroepithelial Tumor Causing Progressive Postpoliomyelitis Paralytic Limb
Congenital Lumbosacral Malformations with Low‐Grade Neuroepithelial Tumor Causing Progressive Postpoliomyelitis Paralytic Limb Open
A 41-year-old woman presented to our orthopedic department with a chief complaint of progressive paralysis and weakness in the left lower extremity for 4 years. She was diagnosed with poliomyelitis at 8 years old and had a postpoliomyeliti…
View article: Enhanced Recovery after Total Joint Arthroplasty (<scp>TJA</scp>): A Contemporary Systematic Review of Clinical Outcomes and Usage of Key Elements
Enhanced Recovery after Total Joint Arthroplasty (<span>TJA</span>): A Contemporary Systematic Review of Clinical Outcomes and Usage of Key Elements Open
Background Enhanced recovery after surgery (ERAS) is a pathway designed to improve the care of surgical patients and achieve early recovery. The clinical outcomes and usage of key elements of ERAS pathways in total joint arthroplasty (TJA)…
View article: Preoperative ultrasound identification and localization of the inferior parathyroid glands in thyroid surgery
Preoperative ultrasound identification and localization of the inferior parathyroid glands in thyroid surgery Open
Introduction The parathyroid glands are important endocrine glands for maintaining calcium and phosphorus metabolism, and they are vulnerable to accidental injuries during thyroid cancer surgery. The aim of this retrospective study was to …
View article: The targets of aspirin in bladder cancer: bioinformatics analysis
The targets of aspirin in bladder cancer: bioinformatics analysis Open
View article: Case report: Unique ultrasound feature of thyroid metastases in occult breast cancer
Case report: Unique ultrasound feature of thyroid metastases in occult breast cancer Open
Occult breast cancer is an uncommon type of breast cancer. Metastases of occult breast cancer to other tissues are rather rare. We present a rare case of thyroid metastases in a 46-year-old woman who underwent occult breast cancer. The fir…
View article: The targets of aspirin in bladder cancer: Bioinformatics analysis
The targets of aspirin in bladder cancer: Bioinformatics analysis Open
Background: The anti-carcinogenic properties of aspirin have been observed in some solid tumors. However, the molecular mechanism of therapeutic effects of aspirin on bladder cancer is still indistinct. We introduced a bioinformatics analy…
View article: Bioinformatics analysis: relationship between adrenocortical carcinoma and KIFs
Bioinformatics analysis: relationship between adrenocortical carcinoma and KIFs Open
Adrenal cortical cancer has a relatively low incidence, but a dismal 5-year survival rate. Surgical intervention is the gold standard of care today. In spite of this progress, patients continue to have a dismal outlook. The results of this…
View article: A Novel Circular RNA hsa_circRPPH1_015 Exerts an Oncogenic Role in Breast Cancer by Impairing miRNA-326-Mediated ELK1 Inhibition
A Novel Circular RNA hsa_circRPPH1_015 Exerts an Oncogenic Role in Breast Cancer by Impairing miRNA-326-Mediated ELK1 Inhibition Open
Background: Breast cancer (BC) represents a heterogeneous disease with distinct subtypes and high tumor metastatic potentials. Recent researchers identify the implication of circular RNAs (circRNAs) in the initiation of BC. Herein, …
View article: Clinicopathological characteristics and survival of malignant fibrous histiocytoma of the bone: A population-based study using the SEER database
Clinicopathological characteristics and survival of malignant fibrous histiocytoma of the bone: A population-based study using the SEER database Open
Malignant fibrous histiocytoma of the bone (MFH-B) is an extremely rare and aggressive malignancy. The clinicopathological characteristics and prognosis of patients with MFH-B have not been defined. We conducted a retrospective study using…
View article: The change of sagital balance after PKP for patients with osteoporotic vertebral compression
The change of sagital balance after PKP for patients with osteoporotic vertebral compression Open
Purpose To detect the postoperative change in total spinal alignment in 0VCF patients after PKP. Methods A total of 130 patients with vertebral compression fracture was involved in this study. The entire spine radiographs of every patients…
View article: Copper-Catalyzed Amination of Vinyl Azides to α-Ketoamides
Copper-Catalyzed Amination of Vinyl Azides to α-Ketoamides Open
An efficient approach for the amination of vinyl azides with N,N-dialkylacylamides has been developed. By using this protocol, structurally important α-ketoamides can be easily synthesized. The key to success is not only the introduction o…
View article: Fine-tuning the expression of target genes using a DDI2 promoter gene switch in budding yeast
Fine-tuning the expression of target genes using a DDI2 promoter gene switch in budding yeast Open
Tuned gene expression is crucial to the proper growth and response to the environmental changes of an organism. To enable tunable gene expression as designed is desirable in both scientific research and industrial application. Here, we int…
View article: The association of XRCC1 polymorphism with osteosarcoma risk, clinicopathologic features, and prognosis in a Chinese Han population
The association of XRCC1 polymorphism with osteosarcoma risk, clinicopathologic features, and prognosis in a Chinese Han population Open
In conclusion, these findings revealed that XRCC1 rs3213245 polymorphism was associated with increased risk of OS, which could affect XRCC1 expression in vitro and in vivo.
View article: Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified &#955; DNA at the Single Molecule Level
Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level Open
The fluorescence microscopy has made great contributions in dissecting the mechanisms of complex biological processes at the single molecule level. In single molecule assays for studying DNA-protein interactions, there are two important fa…
View article: Th17 i IL-17 osiągają wyższe stężenia w przebiegu martwicy głowy kości udowej i są dodatnio skorelowane z nasileniem bólu
Th17 i IL-17 osiągają wyższe stężenia w przebiegu martwicy głowy kości udowej i są dodatnio skorelowane z nasileniem bólu Open
Th17 cells were recruited to an inflamed synovium, and inflammatory cytokine IL-17 was expressed at an increased level in the hip synovium of ONFH patients, which possibly contributed to clinical syndrome development. Overall, this study w…
View article: rs1760944 Polymorphism in the APE1 Region is Associated with Risk and Prognosis of Osteosarcoma in the Chinese Han Population
rs1760944 Polymorphism in the APE1 Region is Associated with Risk and Prognosis of Osteosarcoma in the Chinese Han Population Open
View article: Effector T helper cell populations are elevated in the bone marrow of rheumatoid arthritis patients and correlate with disease severity
Effector T helper cell populations are elevated in the bone marrow of rheumatoid arthritis patients and correlate with disease severity Open
View article: Long-term care for aged ethnic minority people in Yunnan, China: Understanding the situation
Long-term care for aged ethnic minority people in Yunnan, China: Understanding the situation Open
Chinese governmental sectors have been investing lots of money in setting up new institutions for long-term care (LTC) in rural China to respond to the predicted increasing and urgent needs of the growing number of aging people. However, v…
View article: Flow cytometric analysis of Th1 cells, Th22 cells and CD4<sup>+</sup>IFNγ<sup>−</sup>IL17<sup>+</sup>IL-22<sup>+</sup> cells.
Flow cytometric analysis of Th1 cells, Th22 cells and CD4<sup>+</sup>IFNγ<sup>−</sup>IL17<sup>+</sup>IL-22<sup>+</sup> cells. Open
Peripheral blood from patients with AMI, UA, SA and HC subjects were stimulated with PMA, ionomycin and monensin for 4 h, and then stained with labeled antibodies as described in Methods. A, Gating strategies and representative flow cytome…
View article: Prevention and treatment of bone cement-related complications in patients receiving percutaneous kyphoplasty.
Prevention and treatment of bone cement-related complications in patients receiving percutaneous kyphoplasty. Open
With careful surgery, complications associated with bone cement could be greatly reduced.