Keyu Lin
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View article: AIBP-LRP2–mediated HDL uptake restricts CXCR4 <sup>+</sup> stemlike capillary expansion and collateral circulation
AIBP-LRP2–mediated HDL uptake restricts CXCR4 <sup>+</sup> stemlike capillary expansion and collateral circulation Open
The tissue environment governs vascular remodeling, a key determinant of collateral circulation (CC) in ischemic disease, yet the mechanisms driving CC in adults remain unclear. Plasma profiling from patients with peripheral artery disease…
View article: Breaking Latent Prior Bias in Detectors for Generalizable AIGC Image Detection
Breaking Latent Prior Bias in Detectors for Generalizable AIGC Image Detection Open
Current AIGC detectors often achieve near-perfect accuracy on images produced by the same generator used for training but struggle to generalize to outputs from unseen generators. We trace this failure in part to latent prior bias: detecto…
View article: Utilizing an adenosine triphosphate bioluminescence assay as an indicator of instrument and environmental cleanliness in the radiology department: a pilot study
Utilizing an adenosine triphosphate bioluminescence assay as an indicator of instrument and environmental cleanliness in the radiology department: a pilot study Open
View article: Circulating Epstein‒Barr virus microRNA BART8-3p as a potential biomarker for detection and prognostic prediction in early nasopharyngeal carcinoma
Circulating Epstein‒Barr virus microRNA BART8-3p as a potential biomarker for detection and prognostic prediction in early nasopharyngeal carcinoma Open
Backgroud To evaluate the clinical significance of plasma Epstein‒Barr virus (EBV) BamHI A rightward transcript (BART)-encoded microRNA 8-3p (miR-BART8-3p) in patients with early nasopharyngeal carcinoma (NPC). Methods A total of 126 patie…
View article: Triple facilitation therapy in the non-acute stage of post-stroke dyskinesia: protocol for a single-blind randomized controlled trial
Triple facilitation therapy in the non-acute stage of post-stroke dyskinesia: protocol for a single-blind randomized controlled trial Open
Background and purpose: Dyskinesia is a series of movement disorders arising from a stroke. Western medicine focuses on anticoagulation, which can lead to intracranial and gastrointestinal bleeding, and reduce the body's immunity. Traditio…
View article: Hsa_circ_0006692 Promotes Lung Cancer Progression via miR-205-5p/CDK19 Axis
Hsa_circ_0006692 Promotes Lung Cancer Progression via miR-205-5p/CDK19 Axis Open
Circular RNA (CircRNA) is related to tumor development. Nevertheless, the regulation and function of hsa_circ_0006692 and its interactions with miR-205-5p and CDK19 in the development of non-small-cell lung cancer (NSCLC) were un-explored.…
View article: Knockdown of Annexin A2 Enhances Radiosensitivity by Increasing G2/M-Phase Arrest, Apoptosis and Activating the p38 MAPK-HSP27 Pathway in Nasopharyngeal Carcinoma
Knockdown of Annexin A2 Enhances Radiosensitivity by Increasing G2/M-Phase Arrest, Apoptosis and Activating the p38 MAPK-HSP27 Pathway in Nasopharyngeal Carcinoma Open
Annexin A2 (ANXA2) has been found to be involved in cancer proliferation, metastasis and prognosis; however, its exact role in nasopharyngeal carcinoma (NPC) radioresistance remains unknown. We found that ANXA2 expression was correlated wi…
View article: Plasma Epstein-Barr Virus MicroRNA BART8-3p as a Diagnostic and Prognostic Biomarker in Nasopharyngeal Carcinoma
Plasma Epstein-Barr Virus MicroRNA BART8-3p as a Diagnostic and Prognostic Biomarker in Nasopharyngeal Carcinoma Open
Background Nasopharyngeal carcinoma is an Epstein-Barr virus (EBV)-associated tumor that is highly common in southern China. Our previous sequencing data demonstrated that the EBV-encoded microRNA BART8-3p was most upregulated in nasophary…
View article: Competitive Endogenous RNA Landscape in Epstein-Barr Virus Associated Nasopharyngeal Carcinoma
Competitive Endogenous RNA Landscape in Epstein-Barr Virus Associated Nasopharyngeal Carcinoma Open
Non-coding RNAs have been shown to play important regulatory roles, notably in cancer development. In this study, we investigated the role of microRNAs and circular RNAs in Nasopharyngeal Carcinoma (NPC) by constructing a circRNA-miRNA-mRN…
View article: SNHG8 Promotes the Progression of Epstein–Barr Virus-Associated Gastric Cancer via Sponging miR-512-5p and Targeting TRIM28
SNHG8 Promotes the Progression of Epstein–Barr Virus-Associated Gastric Cancer via Sponging miR-512-5p and Targeting TRIM28 Open
SNHG8, a family member of small nucleolar RNA host genes (SNHG), has been reported to act as an oncogene in gastric carcinoma (GC). However, its biological function in Epstein–Barr virus (EBV)-associated gastric cancer (EBVaGC) remains unc…
View article: Expression of circ_0006692 in Non-small Cell Lung Cancer and Its Regulatory Mechanism on Proliferation and Metastasis of Lung Cancer Cells
Expression of circ_0006692 in Non-small Cell Lung Cancer and Its Regulatory Mechanism on Proliferation and Metastasis of Lung Cancer Cells Open
Objective To explore the expression of circ_0006692 in NSCLC and its relation with clinicopathological characteristics and related mechanism. Methods We collected 50 pairs of NSCLC tissues and adjacent tissues. The expression of circ_00066…
View article: The Prognosis Value of PSPC1 Expression in Nasopharyngeal Cancer
The Prognosis Value of PSPC1 Expression in Nasopharyngeal Cancer Open
PSPC1 overexpression was associated with poor prognosis for NPC, which might be a novel useful biomarker to predict the response of NPC to radiation therapy and its clinical outcome.
View article: SNHG8 Promotes the Progression of Epstein-Barr Virus(EBV)--Associated Gastric Cancer Via Sponging miR-512-5p and Targeting TRIM28
SNHG8 Promotes the Progression of Epstein-Barr Virus(EBV)--Associated Gastric Cancer Via Sponging miR-512-5p and Targeting TRIM28 Open
View article: Intratreatment Tumor Volume Change During Definitive Chemoradiotherapy is Predictive for Treatment Outcome of Patients with Esophageal Carcinoma
Intratreatment Tumor Volume Change During Definitive Chemoradiotherapy is Predictive for Treatment Outcome of Patients with Esophageal Carcinoma Open
Ruihong Huang,1 Hong Guo,1 Jianzhou Chen,1,2 Tiantian Zhai,1,3 Junwei Chen,4 Kun Lin,5 Zhijian Chen,6 Derui Li,1 Chuangzhen Chen1 1Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong …
View article: Expression of ARL4C in Non-small Cell Lung Cancer and Its Role in EGFR-TKI Resistance
Expression of ARL4C in Non-small Cell Lung Cancer and Its Role in EGFR-TKI Resistance Open
Objective To investigate the expression of ARL4C in NSCLC and its correlation with clinicopathological features, as well as its role in EGFR-TKI resistance. Methods We collected the tumor and adjacent tissues of 63 NSCLC patients. The mRNA…
View article: Circulating Epstein‐Barr virus microRNAs BART7‐3p and BART13‐3p as novel biomarkers in nasopharyngeal carcinoma
Circulating Epstein‐Barr virus microRNAs BART7‐3p and BART13‐3p as novel biomarkers in nasopharyngeal carcinoma Open
Epstein‐Barr virus (EBV) Bam HI A rightward transcripts (BART) encoded microRNAs (EBV‐miR‐BARTs) are abnormally highly expressed in nasopharyngeal carcinoma (NPC). This study aims to investigate the diagnostic and prognostic performance of…
View article: Diagnostic and prognostic performance of circulating levels of the Epstein-Barr virus microRNAs BART 7-3p and BART 13-3p in nasopharyngeal carcinoma
Diagnostic and prognostic performance of circulating levels of the Epstein-Barr virus microRNAs BART 7-3p and BART 13-3p in nasopharyngeal carcinoma Open
Background Nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV) infection. EBV BamHI A rightward transcripts (BART) encode microRNAs (EBV-miR-BARTs) abnormally highly expressed and play an essential role in NP…
View article: Overexpression of β-Catenin Decreases the Radiosensitivity of Human Nasopharyngeal Carcinoma CNE-2 Cells
Overexpression of β-Catenin Decreases the Radiosensitivity of Human Nasopharyngeal Carcinoma CNE-2 Cells Open
Background/Aims: Nasopharyngeal carcinoma (NPC) is rare worldwide but remains highly prevalent in endemic regions, notably in southern China. Radiotherapy remains the treatment of choice for NPC, but radioresistance has been identified as …