Kaitai Liu
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View article: CCRC: A Change-Aware Captioning and Reasoning Chain for Image Change Captioning and Segmentation
CCRC: A Change-Aware Captioning and Reasoning Chain for Image Change Captioning and Segmentation Open
Understanding and localizing subtle changes between paired images is critical for tasks such as surveillance and image editing. However, traditional Image Change Captioning (ICC) methods lack spatial grounding, limiting their precision. We…
View article: Systematic analysis of doxorubicin-induced myocardial injury mechanisms using network toxicology and molecular docking strategy
Systematic analysis of doxorubicin-induced myocardial injury mechanisms using network toxicology and molecular docking strategy Open
To systematically investigate the molecular mechanisms of doxorubicin (DOX)-induced myocardial injury through network toxicology, molecular docking, and molecular dynamics simulations, aiming to identify critical molecular targets for redu…
View article: Advances in research on RNA methylation and cancer radiotherapy resistance
Advances in research on RNA methylation and cancer radiotherapy resistance Open
RNA methylation is a type of reversible chemical modification in epitranscriptomics that influences gene expression by dynamically regulating RNA functions. RNA methylation comprises N6-methyladenosine (m6A), 5-methylcytosine (m5C), N7-met…
View article: Comparative effectiveness of surgery versus radiotherapy for non-nasopharyngeal head and neck lymphoepithelial carcinoma: An IPTW propensity score analysis
Comparative effectiveness of surgery versus radiotherapy for non-nasopharyngeal head and neck lymphoepithelial carcinoma: An IPTW propensity score analysis Open
Background Lymphoepithelial carcinoma (LEC) is a rare head and neck malignancy predominately treated with radiotherapy or surgery. However, comparative effectiveness studies, are lacking for non-nasopharyngeal head and neck LEC (HNLEC). Me…
View article: Comprehensive identification of a migrasomes-associated long non-coding RNA signature to predict the prognosis and treatment options in colon adenocarcinoma
Comprehensive identification of a migrasomes-associated long non-coding RNA signature to predict the prognosis and treatment options in colon adenocarcinoma Open
View article: CHI3L1 mediates radiation resistance in colorectal cancer by inhibiting ferroptosis via the p53/SLC7A11 pathway
CHI3L1 mediates radiation resistance in colorectal cancer by inhibiting ferroptosis via the p53/SLC7A11 pathway Open
View article: Survival advantage of radiotherapy and nomogram for patients with pulmonary neuroendocrine neoplasms: a propensity score-matched Surveillance, Epidemiology, and End Results database study
Survival advantage of radiotherapy and nomogram for patients with pulmonary neuroendocrine neoplasms: a propensity score-matched Surveillance, Epidemiology, and End Results database study Open
Our findings indicate that RT may provide a survival benefit for patients with pNENs, particularly for those who did not undergo surgery. The nomogram produced in this study may be a used to predict the prognosis of this patient group.
View article: A Functional Stent with Near-Infrared Light Triggered Localized Photothermal-Chemo Synergistic Therapy for Malignant Stenosis of Esophageal Cancer
A Functional Stent with Near-Infrared Light Triggered Localized Photothermal-Chemo Synergistic Therapy for Malignant Stenosis of Esophageal Cancer Open
View article: Unraveling IFI44L’s biofunction in human disease
Unraveling IFI44L’s biofunction in human disease Open
Interferon-induced protein 44-like ( IFI44L ) is regarded as an immune-related gene and is a member of interferon-stimulated genes (ISGs). They participate in network transduction, and its own epigenetic modifications, apoptosis, cell-matr…
View article: Correction to: Cytoglobin augments ferroptosis through autophagic degradation of ferritin in colorectal cancer cells
Correction to: Cytoglobin augments ferroptosis through autophagic degradation of ferritin in colorectal cancer cells Open
View article: Cytoglobin augments ferroptosis through autophagic degradation of ferritin in colorectal cancer cells
Cytoglobin augments ferroptosis through autophagic degradation of ferritin in colorectal cancer cells Open
View article: Causal effects of plasma metabolites on autoimmune hepatitis (AIH): a bidirectional two-sample mendelian randomization study
Causal effects of plasma metabolites on autoimmune hepatitis (AIH): a bidirectional two-sample mendelian randomization study Open
View article: Evaluating the prognostic value of tumor deposits in non-metastatic lymph node-positive colon adenocarcinoma using Cox regression and machine learning
Evaluating the prognostic value of tumor deposits in non-metastatic lymph node-positive colon adenocarcinoma using Cox regression and machine learning Open
Background The 8th AJCC TNM staging for non-metastatic lymph node-positive colon adenocarcinoma patients(NMLP-CA) stages solely by lymph node status, irrespective of the positivity of tumor deposits (TD). This study uses machine learning a…
View article: SLC20A1 is a prospective prognostic and therapy response predictive biomarker in head and neck squamous cell carcinoma
SLC20A1 is a prospective prognostic and therapy response predictive biomarker in head and neck squamous cell carcinoma Open
SLC20A1 overexpression in HNSCC, characterized by increased cellular invasion, migration and proliferation, is a potential prognostic biomarker and therapeutic response indicator.
View article: PP248 Efficacy and safety of fruquintnib plus biweekly TAS-102 and stereotactic body radiotherapy（SBRT） for metastatic colorectal cancer: A multicenter phase II trial
PP248 Efficacy and safety of fruquintnib plus biweekly TAS-102 and stereotactic body radiotherapy（SBRT） for metastatic colorectal cancer: A multicenter phase II trial Open
View article: Biological function and clinical application prospect of tsRNAs in digestive system biology and pathology
Biological function and clinical application prospect of tsRNAs in digestive system biology and pathology Open
tsRNAs are small non-coding RNAs originating from tRNA that play important roles in a variety of physiological activities such as RNA silencing, ribosome biogenesis, retrotransposition, and epigenetic inheritance, as well as involvement in…
View article: A <scp>tRF</scp>‐5a fragment that regulates radiation resistance of colorectal cancer cells by targeting <scp><i>MKNK1</i></scp>
A <span>tRF</span>‐5a fragment that regulates radiation resistance of colorectal cancer cells by targeting <span><i>MKNK1</i></span> Open
Radiotherapy serves as a crucial strategy in the treatment of colorectal cancer (CRC). However, its efficacy is often hindered by the challenge of radiation resistance. Although the literature suggests that some tRNA‐derived small RNAs (ts…
View article: In Situ Characterization of 17-4PH Stainless Steel by Small-Angle Neutron Scattering
In Situ Characterization of 17-4PH Stainless Steel by Small-Angle Neutron Scattering Open
17-4PH martensitic steel is usually used as valve stems in nuclear power plants and it suffers from thermal aging embrittlement due to long-time service in a high-temperature and high-pressure environment. Here, we characterized the evolut…
View article: Survival benefit of radiotherapy and nomogram for patients with primary tracheal malignant tumors: a propensity score-matched SEER database analysis
Survival benefit of radiotherapy and nomogram for patients with primary tracheal malignant tumors: a propensity score-matched SEER database analysis Open
Purpose The purpose of this study was to conduct a matched-pair analysis to assess the impact of radiotherapy (RT) on patients with malignant tracheal tumors using the surveillance, epidemiology, and end results database. Additionally, a p…
View article: Survival benefit of radiotherapy and nomogram for patients with primary tracheal malignant tumors: A Propensity Score-Matched SEER Database Analysis
Survival benefit of radiotherapy and nomogram for patients with primary tracheal malignant tumors: A Propensity Score-Matched SEER Database Analysis Open
Purpose: The purpose of this study was to conduct a matched pair analysis to assess the impact of radiotherapy (RT) on patients with malignant tracheal tumors using the Surveillance, Epidemiology, and End Results (SEER) database. Additiona…
View article: Integrated Analysis of microRNA and RNA-Seq Reveals Phenolic Acid Secretion Metabolism in Continuous Cropping of Polygonatum odoratum
Integrated Analysis of microRNA and RNA-Seq Reveals Phenolic Acid Secretion Metabolism in Continuous Cropping of Polygonatum odoratum Open
Polygonatum odoratum (Mill.) Druce is an essential Chinese herb, but continuous cropping (CC) often results in a serious root rot disease, reducing the yield and quality. Phenolic acids, released through plant root exudation, are typical a…
View article: High eukaryotic initiation factor <scp>5A2</scp> expression predicts poor prognosis and may participate in the <scp>SNHG16</scp>/<scp>miR</scp>‐10b‐5p/<scp>EIF5A2</scp> regulatory axis in head and neck squamous cell carcinoma
High eukaryotic initiation factor <span>5A2</span> expression predicts poor prognosis and may participate in the <span>SNHG16</span>/<span>miR</span>‐10b‐5p/<span>EIF5A2</span> regulatory axis in head and neck squamous cell carcinoma Open
Background This study attempted to investigate the significance of eukaryotic initiation factor 5A2 (EIF5A2) in the prognosis and regulatory network of head and neck squamous cell carcinoma (HNSCC). Methods EIF5A2 expression, prognostic in…
View article: Establishment and validation of a redox-related long non-coding RNAs prognostic signature in head and neck squamous cell carcinoma
Establishment and validation of a redox-related long non-coding RNAs prognostic signature in head and neck squamous cell carcinoma Open
Reduction and oxidation (redox) reactions occur in living organisms as part of normal cellular metabolism. Here, we established a novel redox-related long non-coding RNAs (rrlncRNAs) signature to predict the prognosis and therapeutic respo…
View article: Bioinformatics algorithm for lung adenocarcinoma based on macropinocytosis-related long noncoding RNAs as a reliable indicator for predicting survival outcomes and selecting suitable anti-tumor drugs
Bioinformatics algorithm for lung adenocarcinoma based on macropinocytosis-related long noncoding RNAs as a reliable indicator for predicting survival outcomes and selecting suitable anti-tumor drugs Open
As a highly conserved endocytic mechanism during evolution, macropinocytosis is enhanced in several malignant tumors, which promotes tumor growth by ingesting extracellular nutrients. Recent research has emphasized the crucial role of macr…
View article: Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance
Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance Open
View article: Upregulation of <scp>INHBA</scp> mediated by the transcription factor <scp>BHLHE40</scp> promotes colon cancer cell proliferation and migration
Upregulation of <span>INHBA</span> mediated by the transcription factor <span>BHLHE40</span> promotes colon cancer cell proliferation and migration Open
Background Colon cancer is highly prevalent, and cell proliferation and migration are major reasons for its progression to malignancy. The upregulation of INHBA, a glycoprotein hormone that regulates the secretion of pituitary hormones, is…
View article: Construction of an algorithm based on oncosis‐related LncRNAs comprising the molecular subtypes and a risk assessment model in lung adenocarcinoma
Construction of an algorithm based on oncosis‐related LncRNAs comprising the molecular subtypes and a risk assessment model in lung adenocarcinoma Open
Background As an important non‐apoptotic cell death method, oncosis has been reported to be closely associated with tumors in recent years. However, few research reported the relationship between oncosis and lung cancer. Methods In this st…
View article: The prognostic effect of PNN in digestive tract cancers and its correlation with the tumor immune landscape in colon adenocarcinoma
The prognostic effect of PNN in digestive tract cancers and its correlation with the tumor immune landscape in colon adenocarcinoma Open
Background The present study investigated the expression, mutation, and methylation profile of PNN and its prognostic value in digestive tract cancers. The disparities in signaling pathways and the immune landscape in colon adenocarcinoma …
View article: Construction of an Algorithm Based on Oncosis-Related LncRNAs Comprising the Molecular Subtypes and a Risk Assessment Model in Lung Adenocarcinoma
Construction of an Algorithm Based on Oncosis-Related LncRNAs Comprising the Molecular Subtypes and a Risk Assessment Model in Lung Adenocarcinoma Open
As an important non-apoptotic cell death method, oncosis has been reported to be closely associated with tumors in recent years. However, few researches have reported the relationship between oncosis and lung cancer. In this study, we esta…
View article: Identification of an Autophagy-Related lncRNA Prognostic Signature and Related Tumor Immunity Research in Lung Adenocarcinoma
Identification of an Autophagy-Related lncRNA Prognostic Signature and Related Tumor Immunity Research in Lung Adenocarcinoma Open
Autophagy is closely associated with the tumor immune microenvironment (TIME) and prognosis of patients with lung adenocarcinoma (LUAD). In the present study, we established a signature on the basis of long noncoding RNAs (lncRNAs) related…