Kaitlin E. Sundling
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View article: Gender Inclusion in the Cytopathology Laboratory: Review of Current Practice and Call to Action
Gender Inclusion in the Cytopathology Laboratory: Review of Current Practice and Call to Action Open
Context.— Ensuring equitable laboratory patient care within diverse populations is a priority. The cytopathology laboratory has an important role in providing gender-inclusive care, particularly with regard to screening and prevention of h…
View article: Live-cell analysis of IMPDH protein levels during yeast colony growth provides insights into the regulation of GTP synthesis
Live-cell analysis of IMPDH protein levels during yeast colony growth provides insights into the regulation of GTP synthesis Open
The purine nucleotides ATP and GTP are made from the common precursor inosine monophosphate (IMP). Maintaining the correct balance of these nucleotides for optimal cell growth is controlled in part by the enzyme IMP dehydrogenase (IMPDH), …
View article: The current state of digital cytology and artificial intelligence (AI): global survey results from the American Society of Cytopathology Digital Cytology Task Force
The current state of digital cytology and artificial intelligence (AI): global survey results from the American Society of Cytopathology Digital Cytology Task Force Open
Utilization of digital pathology is limited in cytology laboratories as compared to surgical pathology. However, as more laboratories are willing to implement digital cytology in the near future, the establishment of practical clinical gui…
View article: A platform-independent AI tumor lineage and site (ATLAS) classifier
A platform-independent AI tumor lineage and site (ATLAS) classifier Open
Histopathologic diagnosis and classification of cancer plays a critical role in guiding treatment. Advances in next-generation sequencing have ushered in new complementary molecular frameworks. However, existing approaches do not independe…
View article: The Implementation of Nongynecologic Reporting Systems in Cytopathology Laboratories Is Highly Variable: Analysis of Data From a 2020 Supplemental Survey of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology
The Implementation of Nongynecologic Reporting Systems in Cytopathology Laboratories Is Highly Variable: Analysis of Data From a 2020 Supplemental Survey of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology Open
Context In recent years, several reporting systems have been developed by national and international cytopathology organizations to standardize the evaluation of specific cytopathology specimen types. Objective To assess the current implem…
View article: Navigating Practice Issues Related to the Unsatisfactory Cervicovaginal Papanicolaou Test: Survey Results of Laboratories Participating in the 2020 College of American Pathologists PAP Education Program
Navigating Practice Issues Related to the Unsatisfactory Cervicovaginal Papanicolaou Test: Survey Results of Laboratories Participating in the 2020 College of American Pathologists PAP Education Program Open
Context.— Unsatisfactory Papanicolaou (Pap) tests pose a unique set of challenges to the laboratory with regard to their processing, review, reporting, and performance of human papillomavirus (HPV) testing. There are no standardized guidel…
View article: A clinical-grade liquid biomarker detects neuroendocrine differentiation in prostate cancer
A clinical-grade liquid biomarker detects neuroendocrine differentiation in prostate cancer Open
BackgroundNeuroendocrine prostate cancer (NEPC) is an aggressive subtype, the presence of which changes the prognosis and management of metastatic prostate cancer.MethodsWe performed analytical validation of a Circulating Tumor Cell (CTC) …
View article: Diagnostic Accuracy of Fine-Needle Biopsy in the Detection of Thyroid Malignancy
Diagnostic Accuracy of Fine-Needle Biopsy in the Detection of Thyroid Malignancy Open
Importance Fine-needle biopsy (FNB) became a critical part of thyroid nodule evaluation in the 1970s. It is not clear how diagnostic accuracy of FNB has changed over time. Objective To conduct a systematic review and meta-analysis estimati…
View article: Using American Type Culture Collection Cell Lines to Evaluate Interlaboratory Variables for Estrogen Receptor and Human Epidermal Growth Factor Receptor 2 Immunostaining
Using American Type Culture Collection Cell Lines to Evaluate Interlaboratory Variables for Estrogen Receptor and Human Epidermal Growth Factor Receptor 2 Immunostaining Open
Context.— Most laboratories currently use patient tissues for validating immunohistochemical stains. Objective.— To explore advantages of using cell lines with known antigenicity as a validation method. Design.— Five American Type Culture …
View article: Analytical validation and initial clinical testing of quantitative microscopic evaluation for PD-L1 and HLA I expression on circulating tumor cells from patients with non-small cell lung cancer
Analytical validation and initial clinical testing of quantitative microscopic evaluation for PD-L1 and HLA I expression on circulating tumor cells from patients with non-small cell lung cancer Open
View article: Environmental chemical exposures in the urine of dogs and people sharing the same households
Environmental chemical exposures in the urine of dogs and people sharing the same households Open
Introduction: Urothelial carcinoma (UCC) develops in both humans and dogs and tracks to regions of high industrial activity. We hypothesize that dogs with UCC may act as sentinels for human urothelial carcinogen exposures. The aim of this …
View article: Spotlight: Rising stars in cytology
Spotlight: Rising stars in cytology Open
Daniel Kurtycz, MD Daniel Kurtycz, MD Kaitlin Sundling, MD, PhD, is certainly one of the rising stars in cytopathology. She brings strong science and fresh perspectives to our field. After earning a bachelor's degree in biochemistry and ma…
View article: The science of learning in cytology education
The science of learning in cytology education Open
The current science of learning offers many opportunities to improve cytology education. Although many of us may have made it through our training using traditional methods of rereading and highlighting textbooks, these methods have been s…
View article: Issue Information
Issue Information Open
The diagnostic value of parathyroid hormone washout in primary hyperparathyroidism patients with negative or equivocal 99 m Tc-MIBI results Coverlegend: An example of two cases of squamous cell carcinoma of the lung identified in the LuCED…
View article: Ancillary studies in pleural, pericardial, and peritoneal effusion cytology
Ancillary studies in pleural, pericardial, and peritoneal effusion cytology Open
Pleural, pericardial, and peritoneal effusion specimens present diagnostic challenges and clinical opportunities for cytology. For the patient, these specimens may be the first diagnosis of malignancy or the first sign of disease recurrenc…