Kaiyang Lin
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View article: Unveiling the prognostic power of FIB-4 index: a new frontier in heart failure mortality
Unveiling the prognostic power of FIB-4 index: a new frontier in heart failure mortality Open
FIB-4 is a reliable predictor of all-cause deaths in HF patients.
View article: Proteomics mediates the effects of biological aging on the progression of cardio-renal-metabolic comorbidity: a UK biobank cohort study
Proteomics mediates the effects of biological aging on the progression of cardio-renal-metabolic comorbidity: a UK biobank cohort study Open
Biological aging was strongly associated with the progression of CRM comorbidity, and these associations were partly accounted for by specific circulating proteins. These findings highlight the potential of aging-centered strategies and pr…
View article: Association between the oxidative balance score and all-cause and cardiovascular mortality in patients with cardiovascular-kidney-metabolic syndrome——a retrospective cohort study from the NHANES
Association between the oxidative balance score and all-cause and cardiovascular mortality in patients with cardiovascular-kidney-metabolic syndrome——a retrospective cohort study from the NHANES Open
Higher OBS is linked to reduced all-cause and cardiovascular mortality in CKM patients.
View article: MCPPIR promotes cardiomyocyte proliferation and cardiac repair via o8G oxidation of POC1B mRNA
MCPPIR promotes cardiomyocyte proliferation and cardiac repair via o8G oxidation of POC1B mRNA Open
Aims The adult mammalian heart possesses severely limited regenerative capacity. Cardiomyocyte loss during cardiac injury, coupled with this restricted regenerative potential, represents a fundamental cause of heart failure and associated …
View article: CCL28 contributes to angiogenesis and cardiac repair through CCR10+ endothelial cells after myocardial infarction in male mice
CCL28 contributes to angiogenesis and cardiac repair through CCR10+ endothelial cells after myocardial infarction in male mice Open
Secretome-based therapies that target angiogenesis are promising for the treatment of ischemic heart disease (IHD). The effects of Chemokine C-C motif ligand (CCL) 28 on IHD remain unclear. In this study, we investigated the role of CCL28 …
View article: Association of Serum Cholinesterase with Contrast-Associated Acute Kidney Injury and Adverse Outcomes in Percutaneous Coronary Intervention Patients
Association of Serum Cholinesterase with Contrast-Associated Acute Kidney Injury and Adverse Outcomes in Percutaneous Coronary Intervention Patients Open
Low SChE is an independent risk factor for CA-AKI and a poor prognosis after PCI. Short-term mortality associated with SChE levels is partially mediated through the occurrence of CA-AKI. It is recommended that clinicians evaluate SChE leve…
View article: HDL‐C/LDL‐C Ratio and All‐Cause Mortality in Populations at High CVD Risk: A Prospective Observational Cohort Study
HDL‐C/LDL‐C Ratio and All‐Cause Mortality in Populations at High CVD Risk: A Prospective Observational Cohort Study Open
Background The ratio of high‐density lipoprotein cholesterol (HDL‐C) to low‐density lipoprotein cholesterol (LDL‐C) predicts cardiovascular disease (CVD) endpoints, yet its prognostic validity in high‐risk populations and for type 2 diabet…
View article: Changes in Blood Eosinophil Counts Predict the Death of Patients With Myocardial Infarction After Hospital Discharge
Changes in Blood Eosinophil Counts Predict the Death of Patients With Myocardial Infarction After Hospital Discharge Open
Background Preclinical studies demonstrate a cardioprotective role of eosinophils in acute myocardial infarction. Yet clinical studies show conflicting correlations between blood eosinophil counts and acute myocardial infarction risk and m…
View article: Assessing the causal effect of inflammation‐related genes on myocarditis: A Mendelian randomization study
Assessing the causal effect of inflammation‐related genes on myocarditis: A Mendelian randomization study Open
Aims Prior evidence has shown a significant link between inflammation and the development of myocarditis. This study aimed to investigate the causal relationship between inflammation‐related genes (IRGs) and myocarditis. Methods and result…
View article: The association between systemic inflammatory response index and contrast-associated acute kidney injury in patients undergoing elective percutaneous coronary intervention
The association between systemic inflammatory response index and contrast-associated acute kidney injury in patients undergoing elective percutaneous coronary intervention Open
High levels of SIRI are independent predictors of CA-AKI and long-term mortality in patients undergoing elective PCI.
View article: Healthy lifestyles and rapid progression of carotid plaque in population with atherosclerosis: A prospective cohort study in China
Healthy lifestyles and rapid progression of carotid plaque in population with atherosclerosis: A prospective cohort study in China Open
Healthy lifestyles were associated with lower risk of progression of carotid plaque in populations with atherosclerosis. Promotion of healthy lifestyles from the early stage of carotid atherosclerosis could reduce the burden of CVDs in Chi…
View article: The Association of Intraindividual Difference Between Cystatin- and Creatinine-Based Estimated GFR and Contrast-Associated Acute Kidney Injury
The Association of Intraindividual Difference Between Cystatin- and Creatinine-Based Estimated GFR and Contrast-Associated Acute Kidney Injury Open
There are frequent intraindividual differences between eGFRcys and eGFRcr, and these differences can be used to forecast the risk of CA-AKI.
View article: Lactate dehydrogenase‐to‐albumin ratio: A superior inflammatory marker for predicting contrast‐associated acute kidney injury after percutaneous coronary intervention
Lactate dehydrogenase‐to‐albumin ratio: A superior inflammatory marker for predicting contrast‐associated acute kidney injury after percutaneous coronary intervention Open
Purpose Inflammation is commonly considered a mechanism underlying contrast‐associated acute kidney injury (CA‐AKI). This study aimed to explore the predictive capability of the novel inflammatory marker lactate dehydrogenase‐to‐albumin ra…
View article: A Pilot Study About the Role of PANoptosis-Based Genes in Atherosclerosis Development
A Pilot Study About the Role of PANoptosis-Based Genes in Atherosclerosis Development Open
Our study identified ACP5 and HMOX1 as diagnostic genes for AS that may be associated with PANoptosis. ACP5 and HMOX1 may be involved in the pathogenesis of AS by regulating macrophage PANoptosis.
View article: Assessing the Predictive Value of Different Nutritional Indexes for Contrast-Associated Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention
Assessing the Predictive Value of Different Nutritional Indexes for Contrast-Associated Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention Open
Malnutrition, especially identified by the GNRI and PNI, was associated with a higher risk of CA-AKI after PCI. GNRI and PNI performed better than the CONUT score in predicting CA-AKI.
View article: Association of ambient PM10 and PM2.5 with coronary stenosis measured using selective coronary angiography
Association of ambient PM10 and PM2.5 with coronary stenosis measured using selective coronary angiography Open
Our study provides the first evidence that chronic ambient PM10 and PM2.5 exposure was associated with coronary stenosis assessed by GS in patients with suspected coronary artery disease and reveals its potential mediators.
View article: Prognostic value of triglyceride glucose index in population at high cardiovascular disease risk
Prognostic value of triglyceride glucose index in population at high cardiovascular disease risk Open
Background Early identification of populations at high cardiovascular disease (CVD) risk and improvement of risk factors can significantly decrease the probability of CVD development and improve outcomes. Insulin resistance (IR) is a CVD r…
View article: The optimal definition and prediction nomogram for left ventricular remodelling after acute myocardial infarction
The optimal definition and prediction nomogram for left ventricular remodelling after acute myocardial infarction Open
Aims Left ventricular (LV) remodelling after acute myocardial infarction (AMI) is associated with heart failure and increased mortality. There was no consensus on the definition of LV remodelling, and the prognostic value of LV remodelling…
View article: Predictive Value of Systemic Inflammation Score for Contrast-Associated Acute Kidney Injury and Adverse Outcomes Among Patients Undergoing Elective Percutaneous Coronary Intervention
Predictive Value of Systemic Inflammation Score for Contrast-Associated Acute Kidney Injury and Adverse Outcomes Among Patients Undergoing Elective Percutaneous Coronary Intervention Open
The SIS was closely associated with CA-AKI and long-term mortality in patients after elective PCI. Thus, more attention should be paid to exploring the potential benefits of anti-inflammatory strategies in preventing CA-AKI and improving t…
View article: Prognostic impact of dynamic evolution in renal function among patients undergoing elective percutaneous coronary intervention
Prognostic impact of dynamic evolution in renal function among patients undergoing elective percutaneous coronary intervention Open
Background Previous studies have shown that chronic kidney disease(CKD) affected the long-term prognosis of patients underwent the elective percutaneous coronary intervention(EPCI). However, the prognostic impact in patients with the devel…
View article: Shrunken Pore Syndrome: A New and More Powerful Phenotype of Renal Dysfunction Than Chronic Kidney Disease for Predicting Contrast‐Associated Acute Kidney Injury
Shrunken Pore Syndrome: A New and More Powerful Phenotype of Renal Dysfunction Than Chronic Kidney Disease for Predicting Contrast‐Associated Acute Kidney Injury Open
Background Shrunken pore syndrome (SPS) as a novel phenotype of renal dysfunction is characterized by a difference in renal filtration between cystatin C and creatinine. The manifestation of SPS was defined as a cystatin C–based estimated …
View article: Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review
Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review Open
Extranodal NK/T-cell lymphoma (ENKTL) is a rare but aggressive subtype of non-Hodgkin lymphoma, which is derived from NK cells or T cells. There are very few cases of ENKTL invading the heart. Only 12 cases of ENKTL invading the heart have…
View article: Predictive Value of N-Terminal Pro B-Type Natriuretic Peptide for Contrast-Induced Nephropathy Non-Recovery and Poor Outcomes Among Patients Undergoing Percutaneous Coronary Intervention
Predictive Value of N-Terminal Pro B-Type Natriuretic Peptide for Contrast-Induced Nephropathy Non-Recovery and Poor Outcomes Among Patients Undergoing Percutaneous Coronary Intervention Open
Preprocedural NT-proBNP was associated with CIN non-recovery among patients undergoing PCI. The optimal cut-off value for NT-proBNP to predict CIN non-recovery was 876.1 pg/mL.
View article: Comprehensive Analysis of Differentially Expressed lncRNAs in the Perivascular Adipose Tissue of Patients with Coronary Heart Disease
Comprehensive Analysis of Differentially Expressed lncRNAs in the Perivascular Adipose Tissue of Patients with Coronary Heart Disease Open
Background: Coronary heart disease is a highly prevalent inflammatory disease caused by coronary atherosclerosis. Numerous studies have revealed that perivascular adipose tissue is closely associated with atherosclerosis. Here, we conducte…
View article: Syncope as the Initial Manifestation of Advanced Nasopharyngeal Carcinoma: A Case Report
Syncope as the Initial Manifestation of Advanced Nasopharyngeal Carcinoma: A Case Report Open
Carotid sinus syndrome is a principal cause of syncope in the elderly. Syncope, associated with carotid sinus syndrome which is secondary to metastasis of advanced nasopharyngeal carcinoma, rarely occurs. The current study reported a 66-ye…