Kamyar Esmaeili Pourfarhangi
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View article: Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle
Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle Open
The process of tumor cell invasion and metastasis includes assembly of invadopodia, protrusions capable of degrading the extracellular matrix (ECM). The effect of cell cycle progression on invadopodia has not been elucidated. In this study…
View article: Invadopodia Dynamics is Regulated by ECM Cross-Linking
Invadopodia Dynamics is Regulated by ECM Cross-Linking Open
View article: Invadopodia degrade ECM in the G1 phase of the cell cycle
Invadopodia degrade ECM in the G1 phase of the cell cycle Open
Invadopodia are cancer cell protrusions rich in structural proteins (e.g. Tks5, cortactin) and proteases (e.g. MT1-MMP) and are responsible for degradation of the extracellular matrix (ECM). Tumor cell invasion and metastasis require cance…
View article: Contact guidance is cell cycle-dependent
Contact guidance is cell cycle-dependent Open
Cancer cell migration is essential for metastasis, during which cancer cells move through the tumor and reach the blood vessels. In vivo, cancer cells are exposed to contact guidance and chemotactic cues. Depending on the strength of such …
View article: Directed, but not random, breast cancer cell migration is faster in the G1 phase of the cell cycle in 2D and 3D environments
Directed, but not random, breast cancer cell migration is faster in the G1 phase of the cell cycle in 2D and 3D environments Open
Cancer cell migration is essential for the early steps of metastasis, during which cancer cells move through the primary tumor and reach the blood vessels. In vivo, cancer cells are exposed to directional guidance cues, either soluble, suc…
View article: ECM Cross-Linking Regulates Invadopodia Dynamics
ECM Cross-Linking Regulates Invadopodia Dynamics Open
View article: Intravital Imaging of Tumor Cell Motility in the Tumor Microenvironment Context
Intravital Imaging of Tumor Cell Motility in the Tumor Microenvironment Context Open