Kanaka Shetty
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View article: Use of Clinical Trial Characteristics to Estimate Costs of New Drug Development
Use of Clinical Trial Characteristics to Estimate Costs of New Drug Development Open
Importance Despite their importance to patients, health, and industry, the magnitude of investments in drug research and development (R&D) remain nebulous. New policies require more granular and transparent R&D cost estimat…
View article: Surgical appropriateness nudges: Developing behavioral science nudges to integrate appropriateness criteria into the decision making of spine surgeons
Surgical appropriateness nudges: Developing behavioral science nudges to integrate appropriateness criteria into the decision making of spine surgeons Open
Background Substantial variation exists in surgeon decision making. In response, multiple specialty societies have established criteria for the appropriate use of spine surgery. Yet few strategies exist to facilitate routine use of appropr…
View article: Variations in surgical practice and short-term outcomes for degenerative lumbar scoliosis and spondylolisthesis: do surgeon training and experience matter?
Variations in surgical practice and short-term outcomes for degenerative lumbar scoliosis and spondylolisthesis: do surgeon training and experience matter? Open
For diverse procedures, sizable geographic variation exists in rates and outcomes of surgery, including for degenerative lumbar spine conditions. Little is known about how surgeon training and experience are associated with surgeon-level v…
View article: Trends in the Concurrent Prescription of Opioids and Gabapentin in the US, 2006 to 2018
Trends in the Concurrent Prescription of Opioids and Gabapentin in the US, 2006 to 2018 Open
This cohort study examines trends in concurrent gabapentin and opioid prescribing in the US, overall and by prescriber, patient, and county characteristics, between 2006 and 2018.
View article: Systematic Review on Noninvasive Nonpharmacological Treatment for Chronic Pain: Surveillance Report 3
Systematic Review on Noninvasive Nonpharmacological Treatment for Chronic Pain: Surveillance Report 3 Open
This is the third and final update for the 2020 report Noninvasive Nonpharmacological Treatment for Chronic Pain 1 (available at https://effectivehealthcare.ahrq.gov/products/noninvasive-nonpharm-pain-update/research),covering the period J…
View article: Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 1
Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 1 Open
Background and PurposeThis is the third and final surveillance report for the 2020 report Opioid Treatments for Chronic Pain 1 (https://effectivehealthcare.ahrq.gov/products/opioids-chronic-pain/research),covering the period December 2021 …
View article: Estimated Savings From International Reference Pricing for Prescription Drugs
Estimated Savings From International Reference Pricing for Prescription Drugs Open
This study estimates what 2020 national US savings would have been using international reference pricing rather than US manufacturer and net prices for insulins and 50 top brand-name drugs.
View article: Effect of the ExactCare medication care management model on adherence, health care utilization, and costs
Effect of the ExactCare medication care management model on adherence, health care utilization, and costs Open
BACKGROUND: Multimorbidity and polypharmacy are common in the United States and are associated with greater risk of disease-related complications and higher health care costs. ExactCare has implemented a high-touch approach that includes h…
View article: Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments
Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments Open
Purpose of ProjectTo develop and test text word-only search strategies without MEDLINE ® indexing for three chronic pain living reviews, test a machine classifier on studies identified using the text word search strategies, and apply the m…
View article: Development of Palliative Care Quality Measures for Outpatients in a Clinic-Based Setting: A Report on Information Gathering Activities
Development of Palliative Care Quality Measures for Outpatients in a Clinic-Based Setting: A Report on Information Gathering Activities Open
Palliative care has expanded rapidly in recent years. Hence, there has been a growing awareness of and emphasis on the importance of developing quality measures specific to palliative care. This article describes information-gathering acti…
View article: Economic Evaluation of Quality Improvement Interventions Designed to Improve Glycemic Control in Diabetes: A Systematic Review and Weighted Regression Analysis
Economic Evaluation of Quality Improvement Interventions Designed to Improve Glycemic Control in Diabetes: A Systematic Review and Weighted Regression Analysis Open
OBJECTIVE Quality improvement (QI) interventions can improve glycemic control, but little is known about their value. We systematically reviewed economic evaluations of QI interventions for glycemic control among adults with type 1 or type…
View article: Technical Quality and Clinical Acceptability of a Utilization Review Guideline for Occupational Conditions: ODG® Treatment Guidelines by the Work Loss Data Institute
Technical Quality and Clinical Acceptability of a Utilization Review Guideline for Occupational Conditions: ODG® Treatment Guidelines by the Work Loss Data Institute Open
The Official Disability Guidelines (ODG) Medical Treatment Guidelines is a utilization review guideline used in the field of workers' compensation. This report describes the quality of the methods used to develop ODG as well as the guideli…