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View article: Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration
Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration Open
Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM). Improving nucleus pulposus cells (NPCs) condition first requires a supportive surroundin…
View article: β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration
β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration Open
Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the global economy and healthcare systems. However, no ef…
View article: T2-weighted MRI high signal in cervical spondylotic myelopathy is associated with dynamic change
T2-weighted MRI high signal in cervical spondylotic myelopathy is associated with dynamic change Open
Cervical cord compression worsens with cervical dynamic change from flexion to extension. The degree of compression change is considered a risk factor for high signals on MRI-T2WI. An extension/flexion value greater than 1.4 indicates an i…
View article: SPP1‐ITGα5/β1 Accelerates Calcification of Nucleus Pulposus Cells by Inhibiting Mitophagy via Ubiquitin‐Dependent PINK1/PARKIN Pathway Blockade
SPP1‐ITGα5/β1 Accelerates Calcification of Nucleus Pulposus Cells by Inhibiting Mitophagy via Ubiquitin‐Dependent PINK1/PARKIN Pathway Blockade Open
Low back pain (LBP) caused by nucleus pulposus degeneration and calcification leads to great economic and social burden worldwide. Unexpectedly, no previous studies have demonstrated the association and the underlying mechanism between nuc…
View article: Analysis of risk factors and establishment of prediction model for lower extremity deep vein thrombosis after lumbar fusion surgery
Analysis of risk factors and establishment of prediction model for lower extremity deep vein thrombosis after lumbar fusion surgery Open
The study identified weakened lower extremity muscle strength, intraoperative blood loss, walking impairment, and Venous reflux/ Varicose veins as risk factors for LEDVT formation following lumbar fusion surgery. The predictive tool establ…
View article: Preparation and performance of the non-platinum catalyst for oxygen reduction reaction in fuel cells
Preparation and performance of the non-platinum catalyst for oxygen reduction reaction in fuel cells Open
The oxygen reduction reaction (ORR) of the fuel cells is a core of energy conversion, whereas its kinetics is slow due to the limitation of the activation energy barrier, which dramatically limits the commercial development of fuel cells. …
View article: Synthesis of biomass nitrogen-doped catalysts and their electrocatalytic performance in fuel cells
Synthesis of biomass nitrogen-doped catalysts and their electrocatalytic performance in fuel cells Open
At present, biomass materials have the characteristics of low cost, stability, and relatively high activity, which is expected to replace platinum-based (Pt) materials as cathode catalysts. In this paper, Zn, Fe-N-C catalyst materials and …
View article: Research on the performance of porous ZIF materials in lithium-ion batteries
Research on the performance of porous ZIF materials in lithium-ion batteries Open
Porous materials have attracted more and more attention in the application of lithium-ion batteries (LIBs), which can improve their performance. Herein, a porous zeolite imidazolate skeleton structure material (ZIF-8@ZIF-67) was manufactur…
View article: Analysis of risk factors and establishment of prediction model for lower extremity deep vein thrombosis after lumbar fusion surgery
Analysis of risk factors and establishment of prediction model for lower extremity deep vein thrombosis after lumbar fusion surgery Open
Background Lower extremity deep vein thrombosis (LEDVT) is a common complication after orthopedic surgery. Currently, a reliable assessment tool is lacking to evaluate the risk of postoperative LEDVT in patients undergoing lumbar fusion su…