Kangning Yao
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View article: Analysis of Investment Indicators for the Electronic Components Sector of the A-Share Market
Analysis of Investment Indicators for the Electronic Components Sector of the A-Share Market Open
Contemporarily, the securities market of China has undergone rapid development and become more and more prosper.In the wave of the times, investors need more countermeasures and methods.Based on the "RiceQuant" quantitative investment anal…
View article: Transcriptomic profiling of a multiethnic pediatric NAFLD cohort reveals genes and pathways associated with disease
Transcriptomic profiling of a multiethnic pediatric NAFLD cohort reveals genes and pathways associated with disease Open
Nonalcoholic fatty liver disease (NAFLD) is the most common type of chronic liver disease in children. The mechanisms that drive NAFLD disease progression in this specific patient population remain poorly defined. In this study, we obtaine…
View article: Hepatocyte Stress Increases Expression of Yes‐Associated Protein and Transcriptional Coactivator With PDZ‐Binding Motif in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis
Hepatocyte Stress Increases Expression of Yes‐Associated Protein and Transcriptional Coactivator With PDZ‐Binding Motif in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis Open
Background and Aims Activated hepatocytes are hypothesized to be a major source of signals that drive cirrhosis, but the biochemical pathways that convert hepatocytes into such a state are unclear. We examined the role of the Hippo pathway…
View article: Histone acetyltransferase CBP promotes function of SCF FBXL19 ubiquitin E3 ligase by acetylation and stabilization of its F‐box protein subunit
Histone acetyltransferase CBP promotes function of SCF FBXL19 ubiquitin E3 ligase by acetylation and stabilization of its F‐box protein subunit Open
Ubiquitin E3 ligases mediate ubiquitination and degradation of intracellular proteins. We have shown that a relatively new Skp, Cullin, F‐box (SCF) protein E3 ligase, SCF FBXL19, has an anti‐inflammatory effect and controls actin cytoskele…