Kanwal Haneef
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View article: Role of hydrogen peroxide preconditioning in mesenchymal stem cell-mediated heart regeneration: Molecular insights
Role of hydrogen peroxide preconditioning in mesenchymal stem cell-mediated heart regeneration: Molecular insights Open
Mesenchymal stem cells (MSCs) possess unique properties such as immunomodulation, paracrine actions, multilineage differentiation, and self-renewal. Therefore, MSC-based cell therapy is an innovative approach to treating various degenerati…
View article: Valproic Acid-Induced Hepatocyte-Like Differentiation of Human Amniotic Epithelial Stem Cells in 2D Microenvironment
Valproic Acid-Induced Hepatocyte-Like Differentiation of Human Amniotic Epithelial Stem Cells in 2D Microenvironment Open
This experimental in-vitro study assessed the effectiveness of the 21-day differentiation of human amniotic epithelial cells (hAECs) into hepatic-like cells (HLC), displaying hepatocytes with functional features using culture media supplem…
View article: Human amniotic epithelial cells (HAECS); a potential cell type for the hepatic disorders
Human amniotic epithelial cells (HAECS); a potential cell type for the hepatic disorders Open
Objective: To isolate a homogenous population of human amniotic epithelial cells (hAECs) from the amniotic membrane of the human placenta and differentiate them into hepatic-like cells with the help of small molecules. Method: hAECs were i…
View article: 2,4 -Dinitrophenol Trans-Differentiate NIH3T3 Cells into Insulin Producing β-Cells
2,4 -Dinitrophenol Trans-Differentiate NIH3T3 Cells into Insulin Producing β-Cells Open
diabetes, 2,4-Dinitrophenol, reoxygenationDiabetes is one of the most common diseases worldwide.Type I diabetes is characterized by the degeneration of β-cells.The present study is an attempt in the search of a suitable and efficient way t…
View article: Mesenchymal Stem Cell-Derived Exosomes and Their MicroRNAs in Heart Repair and Regeneration
Mesenchymal Stem Cell-Derived Exosomes and Their MicroRNAs in Heart Repair and Regeneration Open
Mesenchymal stem cells (MSCs) can be differentiated into cardiac, endothelial, and smooth muscle cells. Therefore, MSC-based therapeutic approaches have the potential to deal with the aftermaths of cardiac diseases. However, transplanted s…
View article: Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells
Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells Open
BACKGROUND: Heart diseases are the primary cause of death all over the world. Following myocardial infarction, billions of cells die, resulting in a huge loss of cardiac function. Stem cell-based therapies have appeared as a new area to su…
View article: Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model
Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model Open
Combination of 3D collagen scaffold and zebularine treatment enhances cardiac differentiation potential of MSCs, improves cell engraftment at the infarcted region, reduces infarct size and improves cardiac function.
View article: Proliferation Capacity and Expression of Cell Cycle Genes in Normal and Gestational Diabetes Affected WJMSCs
Proliferation Capacity and Expression of Cell Cycle Genes in Normal and Gestational Diabetes Affected WJMSCs Open
Wharton’s jelly derived mesenchymal stem cells (WJMSCs) are a well-known source for the regenerative approach. Current investigation shows that the metabolic disorders like gestational diabetes mellitus (GDM) are not only responsible for s…
View article: Isolation of Homogenous Population of Human Amniotic Epithelial Stems Cells
Isolation of Homogenous Population of Human Amniotic Epithelial Stems Cells Open
Background: Regenerative medicine is a collaborative field that applies combined concepts of tissue engineering and cell biology to promote regeneration. Tissue regeneration initiate the emergence of remedies that can replace and revive ti…
View article: MEVASTATIN: A NOVEL AGENT FORMING DOPAMINERGIC NEURONS FROM HUMAN MESENCHYMAL STEM CELLS
MEVASTATIN: A NOVEL AGENT FORMING DOPAMINERGIC NEURONS FROM HUMAN MESENCHYMAL STEM CELLS Open
Background: Human umbilical cord derived mesenchymal stem cell (hUMSCs) are in experimental phase for treatment of various neurological disorders. Differentiating these cells into neurons is expensive and painstaking. Mevastatin a commonly…
View article: Human Patellar Bone Dust has Osteogenic Potential: An in vitro Study
Human Patellar Bone Dust has Osteogenic Potential: An in vitro Study Open
Aims: To substantiate the osteogenic differentiation of human Umbilical cord Mesenchymal Stem Cells (hUMSCs) under the influence of Bone Dust (BD) by detecting expression of genes RUNX2 and IBSP in the differentiated cells. Study Design: I…
View article: A Comparative Analysis of Wound Healing Potential, Cell Viability and Morphology of Normal and Gestational Diabetic Affected Wharton’s Jelly Derived Mesenchymal Stem Cells
A Comparative Analysis of Wound Healing Potential, Cell Viability and Morphology of Normal and Gestational Diabetic Affected Wharton’s Jelly Derived Mesenchymal Stem Cells Open
Stem cells derived from Wharton’s jelly of human umbilical cord (WJMSCs) are considered as the potential therapeutic agents for regeneration and are a valuable source for stem cell banking. Current investigation shows metabolic disorders a…
View article: Stem Cell Factor Gene Overexpression Enhances the Fusion Potential of Rat Bone Marrow Mesenchymal Stem Cells with Cardiomyocytes
Stem Cell Factor Gene Overexpression Enhances the Fusion Potential of Rat Bone Marrow Mesenchymal Stem Cells with Cardiomyocytes Open
Cardiovascular disorders are major cause of death globally.Regeneration of cardiac tissue with the use of stem cells has appeared as an effective cell-based therapeutic option.Mesenchymal stem cells (MSCs) are the potential candidates for …
View article: Issue Information
Issue Information Open
TK"), who passed away on 20 Feb 2019 at the age of 88, was a pillar of the wound healing community.His role as a trauma surgeon and his curiosity as an investigator emerged over 5 decades ago.He became Director of the Wound Healing Laborat…
View article: Role of interleukin‐7 in fusion of rat bone marrow mesenchymal stem cells with cardiomyocytes in vitro and improvement of cardiac function in vivo
Role of interleukin‐7 in fusion of rat bone marrow mesenchymal stem cells with cardiomyocytes in vitro and improvement of cardiac function in vivo Open
Summary Aims Mesenchymal stem cells ( MSC s) hold significant promise as potential therapeutic candidates following cardiac injury. However, to ensure survival of transplanted cells in ischemic environment, it is beneficial to precondition…