Karam A. Alawa
YOU?
Author Swipe
View article: Validation of the Iowa Head-Mounted Open-Source Perimeter
Validation of the Iowa Head-Mounted Open-Source Perimeter Open
This study demonstrates the validity of the visual field results from the Iowa HMD Open-Source Perimeter which may help expand perimetry access.
View article: Supplementary Table S6 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S6 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
BAP1KDvsWT_HyperMethDecGE: All significantly hypermethylated probes from hypermethylated/downregulated genes (p < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.01 in BAP1KDvs…
View article: Supplementary Table S5 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S5 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
BAP1KDvsWT_HyperMethyl: All significantly hypermethylated probes (FDR < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.01 in BAP1KDvsWT 92.1 and Mel202 cells. BAP1KDvsWT_HypoM…
View article: Supplementary Figure S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Figure S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
BAP1 knockdown alters the epigenomic profile in uveal melanoma (UM) cells. (A) Western blot of tetracycline-inducible 92.1 and Mel202 shBAP1 UM cells without (-) and with (+) induction by doxycycline. (B) Multidimensional scaling (MDS) plo…
View article: Supplementary Table S4 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S4 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
HyperMethvsDecGE_ChrLoc: Chromosomal loci enriched (FDR < 0.05) for hypermethylated/downregulated genes in Class 2 uveal melanomas compared to Class 1 uveal melanomas HypoMethvsIncGE_ChrLoc: Chromosomal loci enriched (FDR < 0.05) for hypom…
View article: Data from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Data from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
Purpose:The strong association between BAP1 mutations and metastasizing Class 2 uveal melanoma (UM) suggests that epigenetic alterations may play a significant role in tumor progression. Thus, we characterized the impact of BAP1<…
View article: Supplementary Table S5 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S5 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
BAP1KDvsWT_HyperMethyl: All significantly hypermethylated probes (FDR < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.01 in BAP1KDvsWT 92.1 and Mel202 cells. BAP1KDvsWT_HypoM…
View article: Supplementary Table S3 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S3 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
HyperMethvsDecGE_Cutoffs: All significantly hypermethylated probes from hypermethylated/downregulated genes (FDR < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.05 in Class 2…
View article: Supplementary Table S6 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S6 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
BAP1KDvsWT_HyperMethDecGE: All significantly hypermethylated probes from hypermethylated/downregulated genes (p < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.01 in BAP1KDvs…
View article: Supplementary Figure S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Figure S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
BAP1 knockdown alters the epigenomic profile in uveal melanoma (UM) cells. (A) Western blot of tetracycline-inducible 92.1 and Mel202 shBAP1 UM cells without (-) and with (+) induction by doxycycline. (B) Multidimensional scaling (MDS) plo…
View article: Supplementary Table S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
Methylation validation probe targets with forward and reverse primers and the optimized annealing temperature
View article: Supplementary Table S2 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S2 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
TCGA_Methyl_DMP: All significantly methylated probes (FDR < 0.05) in Class 2 uveal melanomas compared to Class 1 uveal melanomas from the 80 TCGA cases. JWH_Methyl_DMP: All significantly methylated probes (p < 0.05) in Class 2 uveal melano…
View article: Supplementary Table S3 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S3 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
HyperMethvsDecGE_Cutoffs: All significantly hypermethylated probes from hypermethylated/downregulated genes (FDR < 0.05) with an absolute value (log2(RNA fold change)) > 1 and absolute value (methylation Delta Beta value) > 0.05 in Class 2…
View article: Supplementary Table S4 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S4 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
HyperMethvsDecGE_ChrLoc: Chromosomal loci enriched (FDR < 0.05) for hypermethylated/downregulated genes in Class 2 uveal melanomas compared to Class 1 uveal melanomas HypoMethvsIncGE_ChrLoc: Chromosomal loci enriched (FDR < 0.05) for hypom…
View article: Supplementary Table S2 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S2 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
TCGA_Methyl_DMP: All significantly methylated probes (FDR < 0.05) in Class 2 uveal melanomas compared to Class 1 uveal melanomas from the 80 TCGA cases. JWH_Methyl_DMP: All significantly methylated probes (p < 0.05) in Class 2 uveal melano…
View article: Supplementary Table S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Supplementary Table S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
Methylation validation probe targets with forward and reverse primers and the optimized annealing temperature
View article: Data from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Data from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas Open
Purpose:The strong association between BAP1 mutations and metastasizing Class 2 uveal melanoma (UM) suggests that epigenetic alterations may play a significant role in tumor progression. Thus, we characterized the impact of BAP1<…
View article: The Open Perimetry Initiative: A framework for cross-platform development for the new generation of portable perimeters
The Open Perimetry Initiative: A framework for cross-platform development for the new generation of portable perimeters Open
The Open Perimetry Initiative was formed in 2010 with the aim of reducing barriers to clinical research with visual fields and perimetry. Our two principal tools are the Open Perimetry Interface (OPI) and the visualFields package with anal…
View article: Rose Bengal and Riboflavin Mediated Photodynamic Antimicrobial Therapy Against Selected South Florida <i>Nocardia</i> Keratitis Isolates
Rose Bengal and Riboflavin Mediated Photodynamic Antimicrobial Therapy Against Selected South Florida <i>Nocardia</i> Keratitis Isolates Open
In vitro results for three clinical strains of Nocardia support the possible use of rose bengal PDAT as a complementary treatment of Nocardia keratitis.
View article: The Open Perimetry Initiative: a framework for cross-platform development for the new generation of portable perimeters
The Open Perimetry Initiative: a framework for cross-platform development for the new generation of portable perimeters Open
The Open Perimetry Initiative is fully open source and consists of the Open Perimetry Interface (OPI) and an accompanying package (visualFields) with analytical tools. The OPI package contains an ever-growing number of drivers for commerci…
View article: Deep Learning–Based Retinal Nerve Fiber Layer Thickness Measurement of Murine Eyes
Deep Learning–Based Retinal Nerve Fiber Layer Thickness Measurement of Murine Eyes Open
Automated segmentation using a deep learning-based algorithm for murine eye OCT effectively and rapidly produced nerve fiber layer thicknesses comparable to manual segmentation.
View article: Deep reinforcement learning for optimized visual field analysis
Deep reinforcement learning for optimized visual field analysis Open
View article: Alleviating an Increasingly Burdened Healthcare System with Telemedicine: Anterior Segment
Alleviating an Increasingly Burdened Healthcare System with Telemedicine: Anterior Segment Open
View article: Flipped ophthalmology classroom augmented with case-based learning
Flipped ophthalmology classroom augmented with case-based learning Open
BackgroundAlthough the flipped classroom model provides an effective way to teach ophthalmology to medical students, there are concerns that it overburdens the learner. The purpose of this study was to assess medical students’ perceptions …
View article: Quantifying Visual Photosensitivity in Healthy and Achromatopsia Subjects
Quantifying Visual Photosensitivity in Healthy and Achromatopsia Subjects Open
View article: Rose bengal photodynamic antimicrobial therapy to inhibit Pseudomonas aeruginosa keratitis isolates
Rose bengal photodynamic antimicrobial therapy to inhibit Pseudomonas aeruginosa keratitis isolates Open
View article: Low-cost, smartphone based frequency doubling technology visual field testing using virtual reality
Low-cost, smartphone based frequency doubling technology visual field testing using virtual reality Open
View article: Automated instrument designed to determine visual photosensitivity thresholds
Automated instrument designed to determine visual photosensitivity thresholds Open
The Ocular Photosensitivity Analyzer (OPA), a new automated instrument to quantify the visual photosensitivity thresholds (VPT) in healthy and light sensitive subjects, is described. The OPA generates light stimuli of varying intensities u…
View article: Development of an Automated Segmentation Program to Assess Corneal Suturing Performance of Ophthalmology Residents Using 3D Printed Eye Models
Development of an Automated Segmentation Program to Assess Corneal Suturing Performance of Ophthalmology Residents Using 3D Printed Eye Models Open
View article: Rose bengal-mediated photodynamic antimicrobial therapy to inhibit Pseudomonas aeruginosa isolates in agar plates and contaminated contact lens cases
Rose bengal-mediated photodynamic antimicrobial therapy to inhibit Pseudomonas aeruginosa isolates in agar plates and contaminated contact lens cases Open