Mei‐Ching Yu
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View article: Dynamics of Urine Metabolomics and Tubular Inflammatory Cytokines in Type 1 Diabetes Across Disease Durations
Dynamics of Urine Metabolomics and Tubular Inflammatory Cytokines in Type 1 Diabetes Across Disease Durations Open
Background/Objectives: Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by sustained inflammation, leading to diabetic kidney disease (DKD). This study investigated urinary tubular injury biomarkers and metabolomic profi…
View article: Developing a Label-Free Infrared Spectroscopic Analysis with Chemometrics and Computational Enhancement for Assessing Lupus Nephritis Activity
Developing a Label-Free Infrared Spectroscopic Analysis with Chemometrics and Computational Enhancement for Assessing Lupus Nephritis Activity Open
Patterns of disease and therapeutic responses vary widely among patients with autoimmune glomerulonephritis. This study introduces groundbreaking personalized infrared (IR)-based diagnostics for real-time monitoring of disease status and t…
View article: Intrarenal Resistive Index and Kidney Volume: Key Indicators of Early Diabetic Kidney Disease in Youth-Onset, Long-Duration Type 1 Diabetes
Intrarenal Resistive Index and Kidney Volume: Key Indicators of Early Diabetic Kidney Disease in Youth-Onset, Long-Duration Type 1 Diabetes Open
Background : The aim of this study is to explore the potential of non-invasive, ultrasound-based markers—kidney volume (KV) and intrarenal resistive index (RI)—for predicting early onset ofdiabetic kidney disease (DKD). Additionally, we in…
View article: The pathological spectrum of pediatric kidney disease: 18-Year experience from a single tertiary care center in northern Taiwan
The pathological spectrum of pediatric kidney disease: 18-Year experience from a single tertiary care center in northern Taiwan Open
Our result revealed that the spectrum of biopsy-proven pediatric kidney disease has not changed significantly over the past two decades. Furthermore, proliferative LN, MCD, and primary IgAN continue to be the most common histopathological …
View article: Impact of kidney size on the outcome of diabetic patients receiving hemodialysis
Impact of kidney size on the outcome of diabetic patients receiving hemodialysis Open
Introduction Diabetic patients normally have enlarged or normal-sized kidneys throughout their lifetime, but some diabetic uremic patients have small kidneys. It is uncertain if kidney size could have any negative impact on outcome in hemo…
View article: The Pathological Spectrum of Pediatric Kidney Disease: 18-year Experience From a Single Tertiary Care Center in Northern Taiwan
The Pathological Spectrum of Pediatric Kidney Disease: 18-year Experience From a Single Tertiary Care Center in Northern Taiwan Open
Background : Glomerular disease is one of major causes leading to chronic kidney disease in children worldwide. The recent publications showed the changing spectrum of glomerular disease in certain countries. Therefore, we aimed to evaluat…
View article: Urine metabolic phenotyping in children with nocturnal enuresis and comorbid neurobehavioral disorders
Urine metabolic phenotyping in children with nocturnal enuresis and comorbid neurobehavioral disorders Open
Nocturnal enuresis (NE) is a common problem among 10% school-aged children. The etiologies underlying childhood NE is complex and not fully understood nowadays. Nevertheless, increasing evidence suggests a potential link between neurobehav…
View article: Mortality Risks among Various Primary Renal Diseases in Children and Adolescents on Chronic Dialysis
Mortality Risks among Various Primary Renal Diseases in Children and Adolescents on Chronic Dialysis Open
There is little information available on the association between primary renal disease (PRD) and long-term mortality in the pediatric dialysis population. The objective of this study was to explore mortality risks in children and adolescen…
View article: Management of nocturnal enuresis in Taiwan: Consensus statements of the Taiwan enuresis expert committee
Management of nocturnal enuresis in Taiwan: Consensus statements of the Taiwan enuresis expert committee Open
Nocturnal enuresis causes significant psychological distress to affected children and their family and requires appropriate management. A 12-member expert committee of pediatric urologists and pediatric nephrologists in Taiwan with extensi…
View article: New-onset Atrial Fibrillation is Associated With Polycystic Kidney Disease
New-onset Atrial Fibrillation is Associated With Polycystic Kidney Disease Open
Cardiovascular complications remain the major problems contributing to morbidity and mortality in patients with polycystic kidney disease (PKD). Therefore, the authors hypothesized that atrial fibrillation (AF) is closely associated with P…
View article: Risk of Peripheral Arterial Occlusive Disease in Patients With Systemic Lupus Erythematosus
Risk of Peripheral Arterial Occlusive Disease in Patients With Systemic Lupus Erythematosus Open
Systemic lupus erythematosus (SLE) is associated with atherosclerosis, but the relationship between SLE and peripheral arterial occlusive disease (PAOD) remains unclear. We sought to investigate this relationship by comparing cardiovascula…
View article: Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions Open
Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine and counterregulator of glucocorticoids, is a potential therapeutic target. MIF is markedly different from other cytokines because it is constitutively expressed, sto…