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Over‐expression of FK506‐binding protein FKBP12.6 alters excitation–contraction coupling in adult rabbit cardiomyocytes Open

Christopher M. Loughrey, Tim Seidler, S. Miller, J. Prestle, K.E. MacEachern , et al. · 2004

Chemistry Biology Computer science

This study investigated the function of FK506‐binding protein (FKBP12.6) using adenoviral‐mediated gene transfer to over‐express FKBP12.6 (Ad‐FKBP12.6) in adult rabbit ventricular cardiomyocytes. Infection with a β‐galactosidase‐expressing…

The Relationship between Intracellular [Ca<sup>2+</sup>] and Ca<sup>2+</sup> Wave Characteristics in Permeabilised Cardiomyocytes from the Rabbit Open

Christopher M. Loughrey, K.E. MacEachern, Paul Neary, Godfrey L. Smith · 2002

Chemistry Biology

Spontaneous sarcoplasmic reticulum (SR) Ca 2+ release and propagated intracellular Ca 2+ waves are a consequence of cellular Ca 2+ overload in cardiomyocytes. We examined the relationship between average intracellular [Ca 2+ ] and Ca 2+ wa…

A Study of Equine Pulmonary Blood Vessel Function In Vitro Open

K.E. MacEachern · 1997

Medicine Biology Chemistry

This study characterised the responses of isolated equine pulmonary artery vessels to hypoxia and a range of agonists, and compared responses of isolated bovine pulmonary vessels. In vivo studies have demonstrated an inability of the equin…

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