Karim Saba
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View article: Long-term follow-up after initial negative prostate biopsy—comparison of conventional transrectal ultrasound biopsy and mpMRI/transrectal ultrasound fusion guided biopsy
Long-term follow-up after initial negative prostate biopsy—comparison of conventional transrectal ultrasound biopsy and mpMRI/transrectal ultrasound fusion guided biopsy Open
Men with an initial negative biopsy have a low risk of developing localized, metastatic, or deadly PCa during long-term follow-up. The biopsy technique was not significantly associated with different IRs of significant PCa diagnoses. The e…
View article: Hubungan Regulasi Diri dengan Perilaku Konsumtif Mahasiswa Prodi Bimbingan Konseling Fakultas Keguruan dan Ilmu Pendidikan Universitas Nusa Cendana
Hubungan Regulasi Diri dengan Perilaku Konsumtif Mahasiswa Prodi Bimbingan Konseling Fakultas Keguruan dan Ilmu Pendidikan Universitas Nusa Cendana Open
Self-regulation is an individual's ability to accept and control themselves so that the goals they have set can be achieved. However, in reality there are still students who are unable to control themselves in fulfilling their needs and de…
View article: Management Of Overactive Bladder Syndrome: Efficacy Of New Pharmacological Agents
Management Of Overactive Bladder Syndrome: Efficacy Of New Pharmacological Agents Open
Background: Overactive Bladder Syndrome (OAB) affects millions worldwide, causing frequent and urgent urination with or without incontinence. It disrupts daily life and poses a significant healthcare challenge. Advancements in pharmacologi…
View article: Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy
Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy Open
Prostate-Specific Antigen (PSA) based screening of prostate cancer (PCa) needs refinement. The aim of this study was the identification of urinary biomarkers to predict the Prostate Imaging-Reporting and Data System (PI-RADS) score and the…
View article: BioPrev-C – development and validation of a contemporary prostate cancer risk calculator
BioPrev-C – development and validation of a contemporary prostate cancer risk calculator Open
Objectives To develop a novel biopsy prostate cancer (PCa) prevention calculator (BioPrev-C) using data from a prospective cohort all undergoing mpMRI targeted and transperineal template saturation biopsy. Materials and methods Data of all…
View article: Prospective Multicenter Validation of the Stockholm3 Test in a Central European Cohort
Prospective Multicenter Validation of the Stockholm3 Test in a Central European Cohort Open
The Stockholm3 blood test shows better accuracy in predicting prostate cancer than the more common PSA (prostate-specific antigen) test.
View article: Do Swiss urologists and Swiss internists screen themselves and their relatives for prostate cancer? A questionnaire study
Do Swiss urologists and Swiss internists screen themselves and their relatives for prostate cancer? A questionnaire study Open
PURPOSE: Prostate-specific antigen (PSA) screening for men at risk of prostate cancer is controversial. The current recommendation is to raise awareness of prostate cancer and offer PSA screening in accordance with shared decision- making.…
View article: Therapy decisions after diagnosis of prostate cancer in men with negative prostate MRI
Therapy decisions after diagnosis of prostate cancer in men with negative prostate MRI Open
Background To investigate the clinical implications of magnetic resonance imaging (MRI) negative prostate cancer (PCa) in a cohort of men undergoing transperineal prostate biopsy. Methods We included all men without prior diagnosis of PCa …
View article: Globally accessible end-user-friendly prostate cancer risk prediction tools based on contemporary cohorts with heterogeneous missing risk factors
Globally accessible end-user-friendly prostate cancer risk prediction tools based on contemporary cohorts with heterogeneous missing risk factors Open
Background: Missing risk factors, whether random or not measured at all, across different hospitals and patients provide challenges, both for the developers of online clinical risk tools and the patients trying to use such tools. This pape…
View article: Modified Immunoscore Improves Prediction of Survival Outcomes in Patients Undergoing Radical Cystectomy for Bladder Cancer—A Retrospective Digital Pathology Study
Modified Immunoscore Improves Prediction of Survival Outcomes in Patients Undergoing Radical Cystectomy for Bladder Cancer—A Retrospective Digital Pathology Study Open
To evaluate the prognostic value of a modified Immunoscore (mIS) in a cohort of bladder cancer (BC) patients undergoing radical cystectomy (RC), two tissue microarrays of 159 BC patients were immunohistochemically stained for CD3/CD8/FOXP3…
View article: Identification of Urine Biomarkers to Improve Eligibility for Prostate Biopsy and Detect High-Grade Prostate Cancer
Identification of Urine Biomarkers to Improve Eligibility for Prostate Biopsy and Detect High-Grade Prostate Cancer Open
PCa screening is based on the measurements of the serum prostate specific antigen (PSA) to select men with higher risks for tumors and, thus, eligible for prostate biopsy. However, PSA testing has a low specificity, leading to unnecessary …
View article: Additional file 2 of Accommodating heterogeneous missing data patterns for prostate cancer risk prediction
Additional file 2 of Accommodating heterogeneous missing data patterns for prostate cancer risk prediction Open
Additional file 2: R code for all 1,024 models available at https://riskcalc.org/ExtendedPBCG/ .
View article: Prostate cancer detection rate in men undergoing transperineal template‐guided saturation and targeted prostate biopsy
Prostate cancer detection rate in men undergoing transperineal template‐guided saturation and targeted prostate biopsy Open
Objectives To compare prostate cancer (PCa) detection rate of transperineal template‐guided saturation prostate biopsy (SBx) and multiparametric magnetic resonance imaging (mpMRI)/transrectal ultrasound fusion guided targeted biopsy (TBx).…
View article: Paraneoplastic tubulointerstitial nephritis exacerbated by immune checkpoint inhibitor
Paraneoplastic tubulointerstitial nephritis exacerbated by immune checkpoint inhibitor Open
Background: With the expanding indications and thus broader use of immune checkpoint inhibitors, clinicians are faced with a new kind of immune-related adverse events. Because of their immune modulating effects, immune checkpoint inhibitor…
View article: Accommodating heterogeneous missing data patterns for prostate cancer risk prediction
Accommodating heterogeneous missing data patterns for prostate cancer risk prediction Open
Objective: We compared six commonly used logistic regression methods for accommodating missing risk factor data from multiple heterogeneous cohorts, in which some cohorts do not collect some risk factors at all, and developed an online ris…
View article: Assessment of Diagnostic Yield of Cystoscopy and Computed Tomographic Urography for Urinary Tract Cancers in Patients Evaluated for Microhematuria
Assessment of Diagnostic Yield of Cystoscopy and Computed Tomographic Urography for Urinary Tract Cancers in Patients Evaluated for Microhematuria Open
This study's findings suggest that, given the low diagnostic yield of CT urography and the associated risks and costs, limiting its use to high-risk patients older than 50 years is warranted. Risk stratification, as recommended by the rece…
View article: Prospective multicentre randomized study to compare holmium laser enucleation of prostate and laparoscopic/robot-assisted simple prostatectomy in high volume prostate glands (≥120 ml)
Prospective multicentre randomized study to compare holmium laser enucleation of prostate and laparoscopic/robot-assisted simple prostatectomy in high volume prostate glands (≥120 ml) Open
The aim of this prospective randomized study is tocompare the perioperative and functional results between laparo-scopic and robot-assisted simple prostatectomy sec. Millin (LSP andRASP) and Holmium laser enucleation of prostate (HoLEP) in…
View article: ProCOC
ProCOC Open
The Prostate Cancer Outcomes Cohort Study Clinical Dataset.
View article: Head-to-head Comparison of Conventional, and Image- and Biomarker-based Prostate Cancer Risk Calculators
Head-to-head Comparison of Conventional, and Image- and Biomarker-based Prostate Cancer Risk Calculators Open
Novel risk calculators (RCs) incorporating imaging improved the ability to discriminate clinically significant prostate cancer compared with traditional tools. However, all but one predicted divergent compared with actual risks, suggesting…
View article: MP55-11 MODIFIED IMMUNOSCORE IMPROVES PREDICTION OF SURVIVAL OUTCOMES IN PATIENTS UNDERGOING RADICAL CYSTECTOMY FOR BLADDER CANCER
MP55-11 MODIFIED IMMUNOSCORE IMPROVES PREDICTION OF SURVIVAL OUTCOMES IN PATIENTS UNDERGOING RADICAL CYSTECTOMY FOR BLADDER CANCER Open
You have accessJournal of UrologyBladder Cancer: Invasive II (MP55)1 Apr 2020MP55-11 MODIFIED IMMUNOSCORE IMPROVES PREDICTION OF SURVIVAL OUTCOMES IN PATIENTS UNDERGOING RADICAL CYSTECTOMY FOR BLADDER CANCER Uwe Bieri*, Buser Lorenz, Maria…
View article: Additional file 6 of Convergent network effects along the axis of gene expression during prostate cancer progression
Additional file 6 of Convergent network effects along the axis of gene expression during prostate cancer progression Open
Additional file 6: Table S5. Proteomics data of 210 PCa samples with duplicates. (a) Sample information includes patient ID, clinical diagnosis, sample ID and batch design. (b) Protein matrix of log2 scaled intensity of 2371 proteins quant…
View article: Additional file 5 of Convergent network effects along the axis of gene expression during prostate cancer progression
Additional file 5 of Convergent network effects along the axis of gene expression during prostate cancer progression Open
Additional file 5: Table S4. RNA-seq analysis. (a) Log2FCs (relative to all benign samples) for all genes across the tumor samples. (b) mRIN score per sample generated using mRIN (v1.2.0). (c) ETS family gene fusions observed in tumor samp…
View article: Additional file 3 of Convergent network effects along the axis of gene expression during prostate cancer progression
Additional file 3 of Convergent network effects along the axis of gene expression during prostate cancer progression Open
Additional file 3: Table S2. Exome analysis of the peripheral blood cells and 105 prostate tumor punches in 39 patients. (a) Allele frequencies (AF) of somatic single nucleotide variants (SNVs) that were called by our bioinformatics pipeli…