Karlijn Hakvoort
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View article: Enhancing decision-making in glioblastoma surgery through an explainable human-AI collaboration: an international multicenter model development and external validation study
Enhancing decision-making in glioblastoma surgery through an explainable human-AI collaboration: an international multicenter model development and external validation study Open
Surgical resection improves survival in glioblastoma, yet predicting the extent of resection (EOR) remains highly challenging. We developed and externally validated an explainable AI model to generate personalized EOR estimates in 811 glio…
View article: A Closer Look at Potential Underlying Factors Related to Possible Disparity Between Sexes in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage
A Closer Look at Potential Underlying Factors Related to Possible Disparity Between Sexes in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Open
Background: Aneurysmal subarachnoid hemorrhage (SAH) is over twice as common in females compared to males, who may also experience more severe hemorrhages and worse outcomes. Differences in SAH severity, susceptibility to delayed cerebral …
View article: Path to success: female leaders in German neurosurgery
Path to success: female leaders in German neurosurgery Open
Despite advances in gender equality, only 6% of German neurosurgical departments are currently led by women. With regard to their pioneering work and the importance of their role model effect, we aimed at reporting on the career pathways o…
View article: 18F-FET-PET-guided gross total resection improves overall survival in patients with WHO grade III/IV glioma: moving towards a multimodal imaging-guided resection
18F-FET-PET-guided gross total resection improves overall survival in patients with WHO grade III/IV glioma: moving towards a multimodal imaging-guided resection Open
Purpose PET using radiolabeled amino acid [ 18 F]-fluoro-ethyl- L -tyrosine (FET-PET) is a well-established imaging modality for glioma diagnostics. The biological tumor volume (BTV) as depicted by FET-PET often differs in volume and locat…
View article: Female Participation in Academic European Neurosurgery—A Cross-Sectional Analysis
Female Participation in Academic European Neurosurgery—A Cross-Sectional Analysis Open
The study aims to provide data on authors’ gender distribution with special attention on publications from Europe. Articles (October 2019–March 2020) published in three representative neurosurgical journals (Acta Neurochirurgica, Journal o…
View article: Shedding light on human cerebral lipofuscin: An explorative study on identification and quantification
Shedding light on human cerebral lipofuscin: An explorative study on identification and quantification Open
Increased oxidative stress has been associated with several neurodegenerative diseases such as Alzheimer's disease, but also with neurological diseases sharing pathophysiological pathways like epilepsy. Lipofuscin is a nondegradable end‐pr…