Kassandra Marsh
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P-952. Optimizing Oral Antimicrobial Therapy at Hospital Discharge: Impact of Antimicrobial Stewardship Pharmacist vs. Team-Based Intervention Open
Background Implementing a formal program for the review of oral antibiotic discharge prescriptions (AbxRx) is often limited by staffing constraints. At our institution, primary teams can choose to reach out to an antimicrobial stewardship …
P-756. Dalbavancin Use at a Large Academic Health System Open
Background Dalbavancin offers an alternative to standard IV antibiotic therapy with its long half-life. Our objective was to evaluate patients who received dalbavancin (DAL) in the emergency department (ED) for acute bacterial skin/skin st…
192. Evaluation Of Oral Vancomycin for Primary Clostridioides difficile Prophylaxis in Hematopoietic Stem Cell Transplant Recipient Patients Open
Background The risk of Clostridioides difficile infection (CDI) is high in patients undergoing hematopoietic stem cell transplant (HSCT) due to many factors including prolonged use of antibiotics. Our institution implemented a protocol inc…
P-1628. Impact of the BioFire® FilmArray® BCID2 Panel and Antimicrobial Stewardship on Clinical Outcomes in Patients with Antimicrobial Resistant Bacteremia Open
Background Bloodstream infections (BSIs) carry high rates of morbidity and mortality, with delays in appropriate therapy associated with worse outcomes. Given limited available literature, our objective was to describe the impact of BioFir…
P-1776. Impact of Sepsis Recognition Tools and Pharmacy Workflow on Sepsis Management and Outcomes Open
Background CDC 2023 Hospital Sepsis Program Core Elements prioritizes protocolized care, timely and effective antibiotics and de-escalation. At NYULH, robust sepsis tools integrated into Epic since July 2021 include the Sepsis Indicator Co…
View article: Antibiotic stewardship bundle for uncomplicated gram-negative bacteremia at an academic health system: a quasi-experimental study
Antibiotic stewardship bundle for uncomplicated gram-negative bacteremia at an academic health system: a quasi-experimental study Open
Objective: To evaluate whether an antimicrobial stewardship bundle (ASB) can safely empower frontline providers in the treatment of gram-negative bloodstream infections (GN-BSI). Intervention and Method: From March 2021 to February 2022, w…
View article: 810. Predictors of 30-Day Mortality Among Critically Ill Patients with Candidemia Identified by T2Candida Panel
810. Predictors of 30-Day Mortality Among Critically Ill Patients with Candidemia Identified by T2Candida Panel Open
Background Candidemia is associated with mortality rates exceeding 40%. However, prior studies indicate mortality may be reduced when antifungal therapy is initiated within 12 hours. The T2Candida Panel is a diagnostic assay that detects C…
222. Oral Step-Down Therapy for Uncomplicated <i>Enterococcus</i> Bacteremia Open
Background The mainstay of therapy for uncomplicated Enterococcal bloodstream infections (BSI) is intravenous (IV) antibiotics which have higher bioavailability than oral (PO) options. This study evaluated clinical outcomes and the safety …
View article: 657. Impact of Oral Vancomycin Duration on <i>Clostridioides difficile</i> Recurrence in Patients Requiring Concurrent Systemic Antibiotics
657. Impact of Oral Vancomycin Duration on <i>Clostridioides difficile</i> Recurrence in Patients Requiring Concurrent Systemic Antibiotics Open
Background IDSA guidelines for the treatment (TX) of Clostridioides difficile infection (CDI) do not provide specific guidance for total duration of oral vancomycin (VAN) TX in patients requiring prolonged concomitant systemic antibiotics …
View article: 1187. Evaluation of an Antimicrobial Stewardship (AS) Bundle for Uncomplicated Gram-Negative Bloodstream Infections (GN-BSI) in Adults at a Large Academic Health System
1187. Evaluation of an Antimicrobial Stewardship (AS) Bundle for Uncomplicated Gram-Negative Bloodstream Infections (GN-BSI) in Adults at a Large Academic Health System Open
Background AS bundles provide concise steps to clinicians at the point of care to guide antibiotic decision-making. At NYULH GN-BSI bundle was implemented in the electronic health record of the microbiology report. The purpose of this proj…
153. Sensitivity of MRSA Nasal Screening in Patients with <i>Staphylococcus aureus</i> Pneumonia: Impact of a More Sensitive Comparator Open
Background Staphylococcus aureus (S. aureus) pneumonia (PNA) is associated with significant morbidity and mortality. Methicillin-resistant Staphylococcus aureus (MRSA) nasal screening has been considered a valuable tool in guiding the de-e…
View article: 2949. Emergency Department (ED) Discharge Antibiotic Prescription Review by Hospital Pharmacists at a Large Academic Medical Center
2949. Emergency Department (ED) Discharge Antibiotic Prescription Review by Hospital Pharmacists at a Large Academic Medical Center Open
Background Direct patient discharge from the Emergency Department (ED) presents an ideal time to promote antimicrobial stewardship (AS). On March 1, 2021 we initiated a pilot program where ED pharmacists conduct a review of discharge antib…
Treatment of Piperacillin-Tazobactam–Nonsusceptible/Ceftriaxone-Susceptible Infections With Carbapenem Versus Carbapenem-Sparing Antimicrobials Open
Background Escherichia coli and Klebsiella pneumoniae with a piperacillin-tazobactam–nonsusceptible/ceftriaxone-susceptible (TZP-NS/CRO-S) phenotype have been increasingly identified, with limited available literature evaluating treatment …
201. Utility of Incorporation of <i>Beta-D-glucan</i> Testing in Algorithms for Diagnosis and Treatment of Candidemia. Open
Background Candidemia is a common hospital acquired infection that is associated with significant morbidity and mortality. The optimal strategy for diagnosis remains unknown. Methods We evaluated 2 distinct diagnostic strategies in hospita…
Outcomes of Cytomegalovirus Viremia Treatment in Critically Ill Patients With COVID-19 Infection Open
Background Patients with coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU) have poor outcomes and frequently develop comorbid conditions, including cytomegalovirus (CMV) reactivation. The implications of CMV rea…
68. Impact of <i>Streptococcus pneumoniae</i> Urinary Antigen Testing in Patients with Community-Acquired Pneumonia Admitted within a Large Academic Medical System Open
Background Limited data support the use of pneumococcal urinary antigen testing (PUAT) for patients admitted with community-acquired pneumonia (CAP) as a stewardship tool to curtail the use of broad-spectrum antimicrobials. At NYULH, CAP g…
Impact of <i>Streptococcus pneumoniae</i> Urinary Antigen Testing in Patients With Community-Acquired Pneumonia Admitted Within a Large Academic Health System Open
Background Limited data support use of pneumococcal urinary antigen testing (PUAT) for patients with community-acquired pneumonia (CAP) as an antimicrobial stewardship tool. At our institution, CAP guidelines and admission order set were s…
Outcomes of COVID-19 Patients Hospitalized at Acute Care Services Open
Background As New York became the epicenter of the COVID-19 pandemic early on, clinicians were challenged to provide optimal medical and pharmaceutical care, despite the paucity of supporting literature and guidance. We sought to describe …
Antithrombotic and hemostatic stewardship: evaluation of clinical outcomes and adverse events of recombinant factor VIIa (Novoseven<sup>®</sup>) utilization at a large academic medical center Open
Background: Recombinant factor VIIa (rFVIIa) (Novoseven®) is utilized for the reversal of anticoagulation-associated bleeding and refractory bleeding in cardiac surgery. In August 2015, rFVIIa was transferred from the blood bank to the pha…