Koloman Krištof
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View article: Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions: results from the I-MOVE and VEBIS multicentre European hospital case–control studies, 2015/16–2023/24
Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions: results from the I-MOVE and VEBIS multicentre European hospital case–control studies, 2015/16–2023/24 Open
View article: Stumpfes Halstrauma mit Dyspnoe
Stumpfes Halstrauma mit Dyspnoe Open
View article: Pneumococcal carriage among young children attending daycare in Hungary, 12–13 years post-PCV13: a cross-sectional study
Pneumococcal carriage among young children attending daycare in Hungary, 12–13 years post-PCV13: a cross-sectional study Open
Nasopharyngeal carriage of Streptococcus pneumoniae in children plays a key role in transmission and disease epidemiology, hence it is crucial to monitor colonisation. As PCV-15 has recently replaced PCV-13 in Hungary, the aim of the study…
View article: Epidemiology, Risk Factors and Mortality of Fungal Bloodstream Infection: 14 Years of Experience at a Teaching Hospital
Epidemiology, Risk Factors and Mortality of Fungal Bloodstream Infection: 14 Years of Experience at a Teaching Hospital Open
Fungal bloodstream infection is a severe condition associated with high mortality rates. Major risk factors of fungal bloodstream infection (BSI) include immunosuppression, abdominal surgery and malignancy. The epidemiology and underlying …
View article: Influenza vaccine effectiveness in Europe and the birth cohort effect against influenza A(H1N1)pdm09: VEBIS primary care multicentre study, 2023/24
Influenza vaccine effectiveness in Europe and the birth cohort effect against influenza A(H1N1)pdm09: VEBIS primary care multicentre study, 2023/24 Open
Introduction Influenza A(H1N1)pdm09, A(H3N2) and B/Victoria viruses circulated in Europe in 2023/24, with A(H1N1)pdm09 dominance. First influenza infections in childhood may lead to different vaccine effectiveness (VE) in subsequent years.…
View article: Enterobacterales abundance in oral cancer patients and elevated clindamycin resistance rates in head and neck infections at a Hungarian Tertiary Hospital
Enterobacterales abundance in oral cancer patients and elevated clindamycin resistance rates in head and neck infections at a Hungarian Tertiary Hospital Open
View article: Genomic characterization of non-O1, non-O139 Vibrio cholerae causing rare clinical manifestation
Genomic characterization of non-O1, non-O139 Vibrio cholerae causing rare clinical manifestation Open
Background Non-O1, non-O139 Vibrio cholerae is an uncommon cause of pneumonia, particularly following freshwater exposure. Non-O1, non-O139 Vibrio cholerae was identified from bronchoalveolar lavage through culture and quantitative polymer…
View article: Felnőtt betegek farmakokinetikai-farmakodinamikai célértékek segítségével vezérelt intravénás kezelése vankomicinnel
Felnőtt betegek farmakokinetikai-farmakodinamikai célértékek segítségével vezérelt intravénás kezelése vankomicinnel Open
A multirezisztens és kiterjedt rezisztenciával rendelkező kórokozók okozta fertőzések jelentős terhet rónak az egészségügyi ellátórendszerre. A hatékony kezelést rugalmasan biztosító, infekció elleni terápiás protokollok bevezetése, a rezi…
View article: Diagnostic and epidemiological landscape of anaerobic bacteria in Europe, 2020–2023 (ANAEuROBE)
Diagnostic and epidemiological landscape of anaerobic bacteria in Europe, 2020–2023 (ANAEuROBE) Open
This study presented an up-to-date analysis of the diagnostics and epidemiology of anaerobic bacteria in Europe, providing insights for future comparative analyses and the development of antimicrobial diagnostic and management strategies, …
View article: Genomic Investigation and Comparative Analysis of European High-Risk Clone of Acinetobacter baumannii ST2
Genomic Investigation and Comparative Analysis of European High-Risk Clone of Acinetobacter baumannii ST2 Open
Multidrug-resistant Acinetobacter baumannii is a major concern in healthcare institutions worldwide. Several reports described the dissemination of A. baumannii high-risk clones that are responsible for a high number of difficult-to-treat …
View article: Characterization of middle ear microbiome in otitis media with effusion in Hungarian children: Alloiococcus otitidis may potentially hamper the microbial diversity
Characterization of middle ear microbiome in otitis media with effusion in Hungarian children: Alloiococcus otitidis may potentially hamper the microbial diversity Open
View article: COVID-19 Vaccine Effectiveness in Autumn and Winter 2022 to 2023 Among Older Europeans
COVID-19 Vaccine Effectiveness in Autumn and Winter 2022 to 2023 Among Older Europeans Open
Importance In the context of emerging SARS-CoV-2 variants or lineages and new vaccines, it is key to accurately monitor COVID-19 vaccine effectiveness (CVE) to inform vaccination campaigns. Objective To estimate the effectiveness of COVID-…
View article: Pathogen genomic surveillance as a scalable framework for precision phage therapy
Pathogen genomic surveillance as a scalable framework for precision phage therapy Open
Phage therapy is gaining increasing interest in the fight against critically resistant nosocomial pathogens. However, the narrow host range of bacteriophages hampers the development of broadly effective phage therapeutics and demands preci…
View article: Vaccine Effectiveness against GP-Attended Symptomatic COVID-19 and Hybrid Immunity among Adults in Hungary during the 2022–2023 Respiratory Season Dominated by Different SARS-CoV-2 Omicron Subvariants
Vaccine Effectiveness against GP-Attended Symptomatic COVID-19 and Hybrid Immunity among Adults in Hungary during the 2022–2023 Respiratory Season Dominated by Different SARS-CoV-2 Omicron Subvariants Open
Hungary provides the opportunity to evaluate the effectiveness of COVID-19 vaccination in a setting where naturally acquired immunity and hybrid immunity are likely to play a greater role due to suboptimal vaccination coverage. Methods: A …
View article: Prevalence, serogroup distribution and risk factors of Neisseria meningitidis carriage in high school and university students in Hungary
Prevalence, serogroup distribution and risk factors of Neisseria meningitidis carriage in high school and university students in Hungary Open
Neisseria meningitidis causes life-threatening invasive meningococcal disease (IMD) with high mortality worldwide. Asymptomatic pharyngeal meningococcus colonisation is an important reservoir for the spread of the bacterium. The aim of thi…
View article: Enterobacterales carrying chromosomal AmpC β-lactamases in Europe (EuESCPM): Epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020–2022
Enterobacterales carrying chromosomal AmpC β-lactamases in Europe (EuESCPM): Epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020–2022 Open
View article: Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network
Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network Open
We conducted a multicentre hospital‐based test‐negative case–control study to measure vaccine effectiveness (VE) against PCR‐confirmed influenza in adult patients with severe acute respiratory infection (SARI) during the 2022/2023 influenz…
View article: Middle Ear Microbiome in Otitis Media with Effusion, the Role of Alloiococcus Otitidis
Middle Ear Microbiome in Otitis Media with Effusion, the Role of Alloiococcus Otitidis Open
View article: Pathogen Genomic Surveillance as a Scalable Framework for Precision Phage Therapy
Pathogen Genomic Surveillance as a Scalable Framework for Precision Phage Therapy Open
View article: The effect of COVID-19 vaccination status on all-cause mortality in patients hospitalised with COVID-19 in Hungary during the delta wave of the pandemic
The effect of COVID-19 vaccination status on all-cause mortality in patients hospitalised with COVID-19 in Hungary during the delta wave of the pandemic Open
The high mortality of patients with coronavirus disease 2019 (COVID-19) is effectively reduced by vaccination. However, the effect of vaccination on mortality among hospitalised patients is under-researched. Thus, we investigated the effec…
View article: Specific nasopharyngeal Corynebacterium strains serve as gatekeepers against SARS-CoV-2 infection
Specific nasopharyngeal Corynebacterium strains serve as gatekeepers against SARS-CoV-2 infection Open
The SARS-CoV-2 virus is still causing a worldwide problem. The virus settles primarily on the nasal mucosa, and the infection and its course depend on individual susceptibility. Our aim was to investigate the nasopharynx composition’s role…
View article: Alsó légúti minták molekuláris mikrobiológiai vizsgálata a koronavírus-járvány időszakában
Alsó légúti minták molekuláris mikrobiológiai vizsgálata a koronavírus-járvány időszakában Open
Bevezetés: A BioFire FilmArray Pneumonia plus Panel (bioMérieux) az alsó légúti fertőzések mikrobiológiai diagnosztikájára kidolgozott „real-time” PCR-rendszer, mely 18 baktérium, 9 vírus és 7 antibiotikum-rezisztenciagén kimutatására képe…
View article: Activated polymorphonuclear derived extracellular vesicles are potential biomarkers of periprosthetic joint infection
Activated polymorphonuclear derived extracellular vesicles are potential biomarkers of periprosthetic joint infection Open
Background Extracellular vesicles (EVs) are considered as crucial players in a wide variety of biological processes. Although their importance in joint diseases or infections has been shown by numerous studies, much less is known about the…
View article: Radiomorphological signs and clinical severity of SARS-CoV-2 lineage B.1.1.7
Radiomorphological signs and clinical severity of SARS-CoV-2 lineage B.1.1.7 Open
Objective: We aimed to assess the differences in the severity and chest-CT radiomorphological signs of SARS-CoV-2 B.1.1.7 and non-B.1.1.7 variants. Methods: We collected clinical data of consecutive patients with laboratory-confirmed COVID…
View article: MICy: a Novel Flow Cytometric Method for Rapid Determination of Minimal Inhibitory Concentration
MICy: a Novel Flow Cytometric Method for Rapid Determination of Minimal Inhibitory Concentration Open
MICy is a new, simple and rapid flow cytometry based antibiotic susceptibility testing (AST) method that produces susceptibility profile a workday earlier than the microdilution method or other classical phenotypic AST methods. Shortening …
View article: In vitro activity of ceftazidime-avibactam and comparators against Enterobacterales and Pseudomonas aeruginosa isolates from Central Europe and Israel, 2014–2017 and 2018
In vitro activity of ceftazidime-avibactam and comparators against Enterobacterales and Pseudomonas aeruginosa isolates from Central Europe and Israel, 2014–2017 and 2018 Open
Between 2014 and 2017, 6,662 Enterobacterales and 1,953 P. aeruginosa isolates were collected by 19 centers in four central European countries and Israel. A further 2,585 Enterobacterales and 707 P. aeruginosa isolates were collected in 20…
View article: EDTA-Induced Pseudothrombocytopenia up to 9 Months after Initial COVID-19 Infection Associated with Persistent Anti-SARS-CoV-2 IgM/IgG Seropositivity
EDTA-Induced Pseudothrombocytopenia up to 9 Months after Initial COVID-19 Infection Associated with Persistent Anti-SARS-CoV-2 IgM/IgG Seropositivity Open
Platelets have a role in vascular complications of COVID-19-related viral coagulopathy. Although immune-induced thrombocytopenia has been described mostly in moderate-to-severe COVID-19, the prognostic role of platelet count in COVID-19 is…
View article: Comparison of virus neutralization activity and results of 10 different anti-SARS-CoV-2 serological tests in COVID-19 recovered plasma donors
Comparison of virus neutralization activity and results of 10 different anti-SARS-CoV-2 serological tests in COVID-19 recovered plasma donors Open
View article: Radio-Morphological Signs and Clinical Severity of Sars-Cov-2 Lineage B.1.1.7
Radio-Morphological Signs and Clinical Severity of Sars-Cov-2 Lineage B.1.1.7 Open
View article: Similar Strains of Coagulase-Negative Staphylococci Found in the Gastrointestinal Tract and Bloodstream of Bacteremic Neonates
Similar Strains of Coagulase-Negative Staphylococci Found in the Gastrointestinal Tract and Bloodstream of Bacteremic Neonates Open
Objectives . Premature neonates are susceptible to opportunistic and nosocomial infections. Efforts have been made to determine whether the neonatal gut microbiome possesses potential for causing bloodstream infections in newborns via micr…