Katarzyna Pankiewicz
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View article: Exploring the Role of miRNA-101a in the Circulatory System’s Adaptive Mechanisms in Hypertensive Disorders of Pregnancy
Exploring the Role of miRNA-101a in the Circulatory System’s Adaptive Mechanisms in Hypertensive Disorders of Pregnancy Open
Background/Objectives: Hypertensive disorders of pregnancy constitute one of the principal reasons for maternal and perinatal morbidity and mortality worldwide. Identification of molecular mechanisms causing placental dysfunction resulting…
View article: Factors influencing endometrial receptivity in women with recurrent implantation failure
Factors influencing endometrial receptivity in women with recurrent implantation failure Open
Not applicable.
View article: Gestational weight gain and blood pressure control in physiological pregnancy and pregnancy complicated by hypertension
Gestational weight gain and blood pressure control in physiological pregnancy and pregnancy complicated by hypertension Open
Background Obesity is a widely recognised risk factor for chronic and gestational hypertension. Influence of gestational weight gain on blood pressure control throughout the pregnancy is not well characterised. Material and methods Women i…
View article: The Impact of Platelet-Rich Plasma Application during Cesarean Section on Wound Healing and Postoperative Pain: A Single-Blind Placebo-Controlled Intervention Study
The Impact of Platelet-Rich Plasma Application during Cesarean Section on Wound Healing and Postoperative Pain: A Single-Blind Placebo-Controlled Intervention Study Open
Background/Objectives: The aim of this study was to evaluate if platelet-rich plasma (PRP) application into the wound during cesarean delivery improves wound healing and reduces pain in the postoperative period. Materials and Methods: A to…
View article: The application of platelet-rich plasma during laparotomy in patients with gynaecological malignancies improves wound healing and reduces postoperative pain feeling – a single-blind placebo controlled intervention study (preliminary report)
The application of platelet-rich plasma during laparotomy in patients with gynaecological malignancies improves wound healing and reduces postoperative pain feeling – a single-blind placebo controlled intervention study (preliminary report) Open
Platelet-rich-plasma application during abdominal closure in gynaecological cancer patients may improve wound healing, as well as reduce pain and the use of analgesics in the early postoperative period.
View article: The current use of the regenerative properties of platelet-rich-plasma in different medical conditions with particular emphasis on gynecology and obstetrics
The current use of the regenerative properties of platelet-rich-plasma in different medical conditions with particular emphasis on gynecology and obstetrics Open
Platelet-rich-plasma (PRP) is a concentrate of plasma containing high levels of platelets and different growth factors, involved in various cellular and regenerative processes, i.a. wound healing and tissue regeneration. Currently, due to …
View article: Understanding the Role of Chemerin in the Pathophysiology of Pre-Eclampsia
Understanding the Role of Chemerin in the Pathophysiology of Pre-Eclampsia Open
Chemerin is a multifaceted adipokine that is involved in multiple biological processes, including inflammation, angiogenesis, adipogenesis, and energy metabolism, as well as oxidative stress. There is a vast body of evidence for a crucial …
View article: The Impact of Coexisting Gestational Diabetes Mellitus on the Course of Preeclampsia
The Impact of Coexisting Gestational Diabetes Mellitus on the Course of Preeclampsia Open
A strict correlation between gestational diabetes mellitus (GDM) and preeclampsia (PE) has been shown in previous studies. This case-control observational study evaluates the influence of concomitant GDM on the severity of PE. Ninety-nine …
View article: Molecular Mechanisms Underlying the Association between Endometriosis and Ectopic Pregnancy
Molecular Mechanisms Underlying the Association between Endometriosis and Ectopic Pregnancy Open
Endometriosis is a common inflammatory disease characterized by the presence of endometrial cells outside the uterine cavity. It is estimated that it affects 10% of women of reproductive age. Its pathogenesis covers a wide range of abnorma…
View article: Genetic Background of Fetal Growth Restriction
Genetic Background of Fetal Growth Restriction Open
Fetal growth restriction (FGR) is one of the most formidable challenges in present-day antenatal care. Pathological fetal growth is a well-known factor of not only in utero demise in the third trimester, but also postnatal morbidity and un…
View article: The Role of Noncoding RNA in the Pathophysiology and Treatment of Premature Ovarian Insufficiency
The Role of Noncoding RNA in the Pathophysiology and Treatment of Premature Ovarian Insufficiency Open
Premature ovarian insufficiency (POI) is defined as a loss of ovarian function before the age of 40 years, with a prevalence rate estimated at approximately 1%. It causes infertility and is related to serious long-term health consequences,…
View article: Insight into the Key Points of Preeclampsia Pathophysiology: Uterine Artery Remodeling and the Role of MicroRNAs
Insight into the Key Points of Preeclampsia Pathophysiology: Uterine Artery Remodeling and the Role of MicroRNAs Open
Preeclampsia affects about 3–8% of all pregnancies. It represents a complex and multifaceted syndrome with at least several potential pathways leading to the development of disease. The main dogma in preeclampsia is the two-stage model of …
View article: The potential association between a new angiogenic marker fractalkine and a placental vascularization in preeclampsia
The potential association between a new angiogenic marker fractalkine and a placental vascularization in preeclampsia Open
Purpose Impaired angiogenesis is one of the most common findings in preeclamptic placentas. A new angiogenetic role of fractalkine (CX3CL1) is recently recognized apart from inflammatory activity. In this study, a link between CX3CL1 and t…
View article: Downregulated expression of microRNAs associated with cardiac hypertrophy and fibrosis in physiological pregnancy and the association with echocardiographically‑evaluated myocardial function
Downregulated expression of microRNAs associated with cardiac hypertrophy and fibrosis in physiological pregnancy and the association with echocardiographically‑evaluated myocardial function Open
The aim of the present study was to analyze the profiles of cardiac microRNAs (miRNAs/miRs) in healthy pregnant women and non-pregnant controls. A total of 61 healthy women >18 years of age with singleton pregnancies in the third trimester…
View article: Non-obstetric complications in preeclampsia
Non-obstetric complications in preeclampsia Open
Preeclampsia is a multisystem disorder of pregnancy that remains a leading cause of maternal and foetal morbidity and mortality. It is still an underestimated risk factor for future cardiovascular, cerebrovascular, and kidney disease, deve…
View article: Rise in antifibrotic and decrease in profibrotic microRNA protect the heart against fibrosis during pregnancy: A preliminary study
Rise in antifibrotic and decrease in profibrotic microRNA protect the heart against fibrosis during pregnancy: A preliminary study Open
In the 3rd trimester of physiological pregnancy, there is a 244% increase in expression of miR-101a and a decrease by 73% in expression of miR-328. Both of these changes can protect against fibrosis during volume overload occurring in phys…
View article: Ovarian Tissue Cryopreservation as a Fertility Sparing Method in Oncological Patients-Current State and Controversy
Ovarian Tissue Cryopreservation as a Fertility Sparing Method in Oncological Patients-Current State and Controversy Open
Global Journal of Endocrinological Metabolism Ovarian Tissue Cryopreservation as a Fertility Sparing Method in Oncological Patients-Current State and Controversy Pankiewicz K1*, Szewczyk G1,2 and Maciejewski TM1 1Department of Obstetrics a…
View article: Perinatal mortality and morbidity of growth restricted fetuses and newborns (own experience) - first report.
Perinatal mortality and morbidity of growth restricted fetuses and newborns (own experience) - first report. Open
1. Gestational age (at diagnosis and at delivery) and birth weight are the most important prognostic factors related to the adverse outcome in the management of fetal growth restriction. 2.The most common mode of delivery for fetuses with …