Katharina J. Huber
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View article: Complete genome sequence of strain AEG42_29 (DSM 112329), a member of the genus <i>Paraconexibacter</i> isolated from soil
Complete genome sequence of strain AEG42_29 (DSM 112329), a member of the genus <i>Paraconexibacter</i> isolated from soil Open
We report the complete genome sequence of strain AEG42_29, a representative of the genus Paraconexibacter isolated from a temperate grassland soil. Its genome codes for several genes involved in stress response, defense, and virulence, whi…
View article: Succession of Bacteria and Archaea Within the Soil Micro‐Food Web Shifts Soil Respiration Dynamics
Succession of Bacteria and Archaea Within the Soil Micro‐Food Web Shifts Soil Respiration Dynamics Open
Bacterivorous nematodes are important grazers in the soil micro‐food web. Their trophic regulation shapes the composition and ecosystem services of the soil microbiome, but the underlying population dynamics of bacteria and archaea are poo…
View article: Edaphobacter paludis sp. nov., a new acidophilic representative of the Acidobacteriota isolated from fen soils
Edaphobacter paludis sp. nov., a new acidophilic representative of the Acidobacteriota isolated from fen soils Open
Two new strains JP48 T and JP55 affiliated with the acidobacterial class Terriglobia have been isolated from fen soil sampled in the Fichtelgebirge Mountains near Bayreuth, Germany. Both strains were Gram-stain-negative, non-motile, non-sp…
View article: Mesorhizobium retamae sp. nov., a novel non-nodulating and non-nitrogen-fixing species isolated from the root nodules of Retama raetam sampled in Tunisia
Mesorhizobium retamae sp. nov., a novel non-nodulating and non-nitrogen-fixing species isolated from the root nodules of Retama raetam sampled in Tunisia Open
A comprehensive polyphasic taxonomic investigation integrating taxongenomic criteria was conducted on strain IRAMC:0171 T isolated from the root nodules of Retama raetam in Tunisia. This Gram-stain-negative and aerobic bacterium thrived wi…
View article: Succession of bacteria and archaea within the soil micro-food web
Succession of bacteria and archaea within the soil micro-food web Open
Bacterivorous nematodes represent numerically abundant bacterial grazers in the soil micro-food web. Their trophic regulation shapes the soil microbiome, but the underlying population dynamics of bacteria and archaea are poorly understood.…
View article: Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics
Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics Open
Objective Head and neck cancer (HNC) accounts for almost 890,000 new cases per year. Radiotherapy (RT) is used to treat the majority of these patients. A common side-effect of RT is the onset of oral mucositis, which decreases the quality …
View article: Baekduia alba sp. nov., a novel representative of the order Solirubrobacterales isolated from temperate grassland soil
Baekduia alba sp. nov., a novel representative of the order Solirubrobacterales isolated from temperate grassland soil Open
Strain 0141_2 T was isolated from a temperate grassland soil in Germany and was found to be affiliated with the order Solirubrobacterales . It is most closely related to Baekduia soli BR7-21 T , with 98.1 % 16S rRNA gene sequence similarit…
View article: Dominance of mixed ether/ester, intact polar membrane lipids in five species of the order Rubrobacterales: Another group of bacteria not obeying the “lipid divide”
Dominance of mixed ether/ester, intact polar membrane lipids in five species of the order Rubrobacterales: Another group of bacteria not obeying the “lipid divide” Open
The composition of the core lipids and intact polar lipids (IPLs) of five Rubrobacter species was examined. Methylated (ω-4) fatty acids (FAs) characterized the core lipids of Rubrobacter radiotolerans, R. xylanophilus and R. bracarensis. …
View article: Evidence for Psammotermes allocerus termite nests as refugium for plant pathogenic microbes: a contribution to generation and maintenance of fairy circles in the Namib Desert
Evidence for Psammotermes allocerus termite nests as refugium for plant pathogenic microbes: a contribution to generation and maintenance of fairy circles in the Namib Desert Open
Fairy circles are circular, barren structures in dry grasslands and the mechanisms generating and maintaining them are currently under intense discussion. Here, we analysed bacterial and fungal communities in Namib Desert fairy circle soil…
View article: Editorial: Acidobacteria – Towards Unraveling the Secrets of a Widespread, Though Enigmatic, Phylum
Editorial: Acidobacteria – Towards Unraveling the Secrets of a Widespread, Though Enigmatic, Phylum Open
EDITORIAL article Front. Microbiol., 24 June 2022Sec. Evolutionary and Genomic Microbiology https://doi.org/10.3389/fmicb.2022.960602
View article: Biopsy-derived oral keratinocytes – A model to potentially test for oral mucosa radiation sensitivity
Biopsy-derived oral keratinocytes – A model to potentially test for oral mucosa radiation sensitivity Open
In vitro propagation of keratinocytes derived from a small biopsy is feasible. Radiation impairs cellular migration and proliferation, and the newly described spreading assay allows ranking for cellular radioresistance. The keratinocyte mo…
View article: Differential Response of Acidobacteria to Water Content, Soil Type, and Land Use During an Extended Drought in African Savannah Soils
Differential Response of Acidobacteria to Water Content, Soil Type, and Land Use During an Extended Drought in African Savannah Soils Open
Although climate change is expected to increase the extent of drylands worldwide, the effect of drought on the soil microbiome is still insufficiently understood as for dominant but little characterized phyla like the Acidobacteria. In the…
View article: The Evolution of Ecological Diversity in Acidobacteria
The Evolution of Ecological Diversity in Acidobacteria Open
Acidobacteria occur in a large variety of ecosystems worldwide and are particularly abundant and highly diverse in soils. In spite of their diversity, only few species have been characterized to date which makes Acidobacteria one of the mo…
View article: Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2‐positive advanced gastric cancer
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2‐positive advanced gastric cancer Open
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancerDear Editor, This study suggests for the first time a metabolomic classifier comprising molecul…
View article: Angucycline-like Aromatic Polyketide from a Novel Streptomyces Species Reveals Freshwater Snail Physa acuta as Underexplored Reservoir for Antibiotic-Producing Actinomycetes
Angucycline-like Aromatic Polyketide from a Novel Streptomyces Species Reveals Freshwater Snail Physa acuta as Underexplored Reservoir for Antibiotic-Producing Actinomycetes Open
Antibiotic producers have mainly been isolated from soil, which often has led to the rediscovery of known compounds. In this study, we identified the freshwater snail Physa acuta as an unexplored source for new antibiotic producers. The ba…
View article: Performance Modelling of the Bioelectrochemical Glycerol Oxidation by a Co‐Culture of <i>Geobacter Sulfurreducens</i> and <i>Raoultella Electrica</i>
Performance Modelling of the Bioelectrochemical Glycerol Oxidation by a Co‐Culture of <i>Geobacter Sulfurreducens</i> and <i>Raoultella Electrica</i> Open
An effectively operating microbial electrolysis cell requires an inexpensive electron donor in combination with a defined and stable electron‐transferring microbial community. Here, a defined co‐culture of Raoultella electrica and Geobacte…
View article: Trophic networks improve the performance of microbial anodes treating wastewater
Trophic networks improve the performance of microbial anodes treating wastewater Open
Microbial anodes represent a distinct ecological niche that is characterized mainly by the terminal electron acceptor, i.e., the anode potential, and the substrate, i.e., the electron source. Here, we determine the performance and the biof…
View article: Concentration Pulse Method for the Investigation of Transformation Pathways in a Glycerol-Fed Bioelectrochemical System
Concentration Pulse Method for the Investigation of Transformation Pathways in a Glycerol-Fed Bioelectrochemical System Open
We investigated transformation pathways and determined rate constants in a continuously operated glycerol-fed bioelectrochemical system under chemostatic conditions by applying concentration pulses of various intermediates. Our methodology…
View article: An overview of the occurrence of ether- and ester-linked iso-diabolic acid membrane lipids in microbial cultures of the Acidobacteria: Implications for brGDGT paleoproxies for temperature and pH
An overview of the occurrence of ether- and ester-linked iso-diabolic acid membrane lipids in microbial cultures of the Acidobacteria: Implications for brGDGT paleoproxies for temperature and pH Open
13,16-Dimethyl octacosanedioic acid (iso-diabolic acid) is a major membrane-spanning lipid of subdivisions (SDs) 1, 3 and 4 of the Acidobacteria, a highly diverse phylum within the Bacteria. It has been suggested that these lipids are pote…
View article: Functional imaging in combination with mutation status aids prediction of response to inhibiting B-cell receptor signaling in lymphoma
Functional imaging in combination with mutation status aids prediction of response to inhibiting B-cell receptor signaling in lymphoma Open
Aberrant B-cell receptor (BCR) signaling is known to contribute to malignant transformation. Two small molecule inhibitors targeting BCR pathway signaling include ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, and idelalisib, a spe…