Katherine M. Morrison
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View article: Central Adiposity and Visceral Fat in Long‐Term Survivors of Acute Lymphoblastic Leukemia in Childhood and Adolescence: Exploration of an Underappreciated Risk
Central Adiposity and Visceral Fat in Long‐Term Survivors of Acute Lymphoblastic Leukemia in Childhood and Adolescence: Exploration of an Underappreciated Risk Open
Introduction Elevated visceral fat is associated with poor cardiovascular health but is not well characterized in survivors of childhood cancer. We examined central adiposity and associated risk factors in a pediatric acute lymphoblastic l…
View article: LOWERING THE DIAGNOSTIC THRESHOLD FOR GESTATIONAL DIABETES: A COMPARISON OF TWO CENTRES
LOWERING THE DIAGNOSTIC THRESHOLD FOR GESTATIONAL DIABETES: A COMPARISON OF TWO CENTRES Open
Failure to optimally treat MH during pregnancy is associated with fetal overgrowth and may affect obstetrical management.
View article: Neighborhood Environments and Changes in Obesity and in Lifestyle Behaviors Among Children Enrolled in Obesity Management Interventions: A Systematic Review
Neighborhood Environments and Changes in Obesity and in Lifestyle Behaviors Among Children Enrolled in Obesity Management Interventions: A Systematic Review Open
Introduction Neighborhood determinants of health have been documented in several populations, yet less is known about their role in pediatric obesity treatment. A systematic review of longitudinal studies examining associations between nei…
View article: Exposure to Metal Mixtures and Childhood Adiposity: An Examination of Periods of Heightened Susceptibility Between Gestation and Late Childhood
Exposure to Metal Mixtures and Childhood Adiposity: An Examination of Periods of Heightened Susceptibility Between Gestation and Late Childhood Open
Introduction Childhood obesity is a public health concern. Studies have investigated the effects of metal mixtures on childhood obesity but none have identified periods of heightened susceptibility of exposure. We identified the periods by…
View article: Feasibility, Reproducibility and Cold-Induced Energy Expenditure using Whole-Room Calorimetry in Adults and Children
Feasibility, Reproducibility and Cold-Induced Energy Expenditure using Whole-Room Calorimetry in Adults and Children Open
Context To understand energy balance, whole-room indirect calorimetry (WRIC) allows for accurate measurement of energy expenditure (EE). Objectives To examine the relationship between cold-induced resting EE and brown adipose tissue (BAT) …
View article: Can muscle avert GLP1R weight plateau and regain?
Can muscle avert GLP1R weight plateau and regain? Open
View article: Hyperglycemia worsens gut bacterial infection through intestinal Wnt, but independent of endotoxemia or obesity
Hyperglycemia worsens gut bacterial infection through intestinal Wnt, but independent of endotoxemia or obesity Open
We show that elevated blood glucose is associated with worse diarrhea during an Escherichia coli outbreak in humans. Obesity or hyperglycemia was sufficient to promote metabolic endotoxemia in humans and mice. Hyperglycemia promotes worse …
View article: Guide de pratique clinique pour la prise en charge de l’obésité chez l’enfant
Guide de pratique clinique pour la prise en charge de l’obésité chez l’enfant Open
CONTEXTE: L’obésité est une maladie chronique complexe et stigmatisante caractérisée par une accumulation anormale ou excessive de graisse corporelle susceptible de nuire à la santé, d’accroître le risque de complications médicales et de r…
View article: Maternal Profiles Account for Birth Weight Differences Across Ethnicities: Results from Three Canadian Birth Cohorts
Maternal Profiles Account for Birth Weight Differences Across Ethnicities: Results from Three Canadian Birth Cohorts Open
Background Marked differences in birth weight (BW) between South Asian and White European-origin populations are well-documented and pose public health concerns. Methods We analyzed fetal BW, the fat mass (FM), and fat-free mass (FFM) comp…
View article: GDF15 links adipose tissue lipolysis with anxiety
GDF15 links adipose tissue lipolysis with anxiety Open
View article: Managing obesity in children: a clinical practice guideline
Managing obesity in children: a clinical practice guideline Open
This guideline will support children, families, and health care providers to have informed discussions about the balance of benefits and harms for available obesity management interventions to support value- and preference-sensitive decisi…
View article: Trajectory of Early Life Adiposity Among South Asian Children
Trajectory of Early Life Adiposity Among South Asian Children Open
Importance Measures of childhood adiposity merit investigation, particularly in individuals of South Asian descent. Objective To investigate prenatal and childhood factors associated with the trajectory of adiposity in South Asian children…
View article: Food supply toxicants and additives alter the gut microbiota and risk of metabolic disease
Food supply toxicants and additives alter the gut microbiota and risk of metabolic disease Open
Metabolic disease is rising along with both global industrialization and the use of new commercial, agricultural, and industrial chemicals and food additives. Exposure to these compounds may contribute to aspects of metabolic diseases such…
View article: Effectiveness of behavioural and psychological interventions for managing obesity in children and adolescents: A systematic review and meta‐analysis framed using minimal important difference estimates based on <scp>GRADE</scp> guidance to inform a clinical practice guideline
Effectiveness of behavioural and psychological interventions for managing obesity in children and adolescents: A systematic review and meta‐analysis framed using minimal important difference estimates based on <span>GRADE</span> guidance to inform a clinical practice guideline Open
Summary Objective Conduct a systematic review and meta‐analysis of randomized controlled trials (RCTs) of behavioural and psychological interventions for managing paediatric obesity. Methods Eligible studies, published between 1985 and 202…
View article: Family Stress and Child BMIz during the COVID-19 Pandemic: Exploring the Mediating Effects of Cortisol
Family Stress and Child BMIz during the COVID-19 Pandemic: Exploring the Mediating Effects of Cortisol Open
Previous research has suggested that children who are exposed to chronic stress are at greater risk for childhood obesity, however little research has examined the mechanism of this association. This study aimed to investigate the associat…
View article: Addressing unmet social needs of children with obesity: a pilot randomized controlled trial
Addressing unmet social needs of children with obesity: a pilot randomized controlled trial Open
View article: Effectiveness of surgical interventions for managing obesity in children and adolescents: A systematic review and meta‐analysis framed using minimal important difference estimates based on <scp>GRADE</scp> guidance to inform a clinical practice guideline
Effectiveness of surgical interventions for managing obesity in children and adolescents: A systematic review and meta‐analysis framed using minimal important difference estimates based on <span>GRADE</span> guidance to inform a clinical practice guideline Open
Summary Objective To summarize the literature on bariatric surgery for managing pediatric obesity, including intervention effects to improve patient‐reported outcome measures (PROMs), cardiometabolic risk factors, anthropometry, and assess…
View article: Author response: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Author response: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
View article: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
Background: Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here, we examine t…
View article: Author response: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Author response: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine the feasibilit…
View article: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine the feasibilit…
View article: Consistent cord blood DNA methylation signatures of gestational age between South Asian and white European cohorts
Consistent cord blood DNA methylation signatures of gestational age between South Asian and white European cohorts Open
Background Epigenetic modifications, particularly DNA methylation (DNAm) in cord blood, are an important biological marker of how external exposures during gestation can influence the in-utero environment and subsequent offspring developme…
View article: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine the feasibilit…
View article: Author response: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Author response: Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine the feasibilit…
View article: Reviewer #2 (Public Review): Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Reviewer #2 (Public Review): Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine the feasibilit…
View article: Reviewer #3 (Public Review): Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Reviewer #3 (Public Review): Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Open
Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine the feasibilit…
View article: The association of red and processed meat with gestational diabetes mellitus: Results from 2 Canadian birth cohort studies
The association of red and processed meat with gestational diabetes mellitus: Results from 2 Canadian birth cohort studies Open
Objective Red and processed meat is considered risk factors of gestational diabetes mellitus (GDM), but the evidence is inconclusive. We aimed to examine the association between red and processed meat intake and odds of GDM among South Asi…
View article: Early Life Exposures and the Development of the Infant Gut Microbiome: A Review
Early Life Exposures and the Development of the Infant Gut Microbiome: A Review Open
The influence of the intestinal microbiota on metabolic, nutritional, and immunological processes is widely reported. With increasing literature associating altered microbial compositions with adverse health outcomes, it is important to un…
View article: Assessment Essentials for HPM Faculty
Assessment Essentials for HPM Faculty Open