Katherine Stuart
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View article: Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department
Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department Open
Background and Objectives The role of viscoelastic haemostatic assays (VHAs) versus conventional coagulation tests (CCTs) in chronic liver disease (CLD) in the emergency department (ED) is undefined. We aimed to characterize VHA profiles a…
View article: Parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: outcomes from LOCATE-NAFLD
Parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: outcomes from LOCATE-NAFLD Open
Objective Non-alcoholic fatty liver disease (NAFLD) is estimated to affect a third of Australian adults, and its prevalence is predicted to rise, increasing the burden on the healthcare system. The LOCal Assessment and Triage Evaluation of…
View article: A parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: Outcomes from LOCATE-NAFLD
A parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: Outcomes from LOCATE-NAFLD Open
Background and Aims Non-alcoholic fatty liver disease (NAFLD) is estimated to affect a third of Australian adults, and its prevalence is predicted to rise, increasing the burden on the healthcare system. LOCATE-NAFLD trialled a community-b…
View article: Comparison of outcomes following surgical resection, percutaneous ablation or stereotactic body radiation therapy in early‐stage, solitary and small (≤3 cm) treatment‐naïve hepatocellular carcinoma
Comparison of outcomes following surgical resection, percutaneous ablation or stereotactic body radiation therapy in early‐stage, solitary and small (≤3 cm) treatment‐naïve hepatocellular carcinoma Open
Introduction Stereotactic body radiation therapy (SBRT) is associated with high local control rates in hepatocellular carcinoma (HCC). This study reports the outcomes of SBRT compared to surgical resection (SR) and percutaneous ablation (P…
View article: Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis
Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis Open
Background: Primary sclerosing cholangitis (PSC) is an immune-mediated, chronic cholestatic liver disease. Currently, liver transplantation is the only established life-saving treatment. Several studies have evaluated the effect of differe…
View article: Changing Prevalence of Medication Use in People with Cirrhosis: A Retrospective Cohort Study Using Pharmaceutical Benefits Scheme Data
Changing Prevalence of Medication Use in People with Cirrhosis: A Retrospective Cohort Study Using Pharmaceutical Benefits Scheme Data Open
Polypharmacy is common in people with cirrhosis and some medication groups may be overused. Pharmacovigilance is required and future medication safety efforts should target high-risk prescribing practices and promote medication rationalisa…
View article: I have always thought a lot about the nature of violence: carceral feminism and sexual violence in the neoliberal state
I have always thought a lot about the nature of violence: carceral feminism and sexual violence in the neoliberal state Open
When the welfare state is dismantled and replaced by a neoliberal state marked by structural racism, feminist movements are affected as well. The development in Sweden is no different from other countries in the West. There is an increasin…
View article: Low Prevalence of Use of Allied Health and Community Services for Patients with Cirrhosis in Australia: A Need for Greater Engagement
Low Prevalence of Use of Allied Health and Community Services for Patients with Cirrhosis in Australia: A Need for Greater Engagement Open
Patients with cirrhosis who have unmet complex physical and psychosocial needs require better strategies to increase their engagement with allied health and community services.
View article: Higher levels of supportive care needs are linked to higher health service use and cost, poor quality of life, and high distress in patients with cirrhosis in Queensland, Australia
Higher levels of supportive care needs are linked to higher health service use and cost, poor quality of life, and high distress in patients with cirrhosis in Queensland, Australia Open
Background: Australians with cirrhosis have significant practical and psychosocial needs. This longitudinal study examined the association between supportive care needs and health service use and costs, and patient outcomes from June 2017 …
View article: Monitoring quality of care in hepatocellular carcinoma: A modified Delphi consensus
Monitoring quality of care in hepatocellular carcinoma: A modified Delphi consensus Open
Although there are several established international guidelines on the management of hepatocellular carcinoma (HCC), there is limited information detailing specific indicators of good quality care. The aim of this study was to develop a co…
View article: Prothrombinex®‐<scp>VF</scp> in chronic liver disease: Friend or foe?
Prothrombinex®‐<span>VF</span> in chronic liver disease: Friend or foe? Open
Objective Management of coagulopathy in chronic liver disease (CLD) poses a challenge for critical care physicians. Prothrombinex®‐VF is a low‐volume product with rapid onset of action. Evidence for its efficacy and safety in CLD is limite…
View article: The Hidden Epidemic: The Prevalence and Impact of Concurrent Liver Diseases in Patients Undergoing Liver Transplantation in Australia and New Zealand
The Hidden Epidemic: The Prevalence and Impact of Concurrent Liver Diseases in Patients Undergoing Liver Transplantation in Australia and New Zealand Open
Background. Prevalence of concurrent liver diseases among liver transplant recipients and impact on posttransplant outcomes are unknown. Methods. This retrospective study included adult liver transplants between January 1‚ 1985‚ and Decemb…
View article: Patient‐oriented medication education intervention has long‐term benefits for people with decompensated cirrhosis
Patient‐oriented medication education intervention has long‐term benefits for people with decompensated cirrhosis Open
Patient barriers to self-management in cirrhosis are complex.[1] Although several studies have demonstrated improved knowledge or self-care behaviors following education,[1] long-term outcome data are lacking. We previously reported that a…
View article: Poor disease knowledge is associated with higher healthcare service use and costs among patients with cirrhosis: an exploratory study
Poor disease knowledge is associated with higher healthcare service use and costs among patients with cirrhosis: an exploratory study Open
Background : Optimal management of cirrhosis is complex, and patients often lack knowledge and skills, which can affect self-management. We assessed patient knowledge about cirrhosis and examined whether knowledge was associated with clini…
View article: Medication Discrepancies and Regimen Complexity in Decompensated Cirrhosis: Implications for Medication Safety
Medication Discrepancies and Regimen Complexity in Decompensated Cirrhosis: Implications for Medication Safety Open
Discrepancies between the medicines consumed by patients and those documented in the medical record can affect medication safety. We aimed to characterize medication discrepancies and medication regimen complexity over time in a cohort of …
View article: Predicting Liver‐Related Outcomes in People With Nonalcoholic Fatty Liver Disease: The Prognostic Value of Noninvasive Fibrosis Tests
Predicting Liver‐Related Outcomes in People With Nonalcoholic Fatty Liver Disease: The Prognostic Value of Noninvasive Fibrosis Tests Open
It remains unclear whether screening for advanced fibrosis in the community can identify the subgroup of people with nonalcoholic fatty liver disease (NAFLD) at higher risk for development of liver‐related complications. We aimed to determ…
View article: Disparities in Unmet Needs in Indigenous and Non-Indigenous Australians with Cirrhosis: An Exploratory Study
Disparities in Unmet Needs in Indigenous and Non-Indigenous Australians with Cirrhosis: An Exploratory Study Open
PURPOSE: Understanding and responding to the supportive care needs of people with cirrhosis is essential to quality care. Indigenous Australians, Aboriginal and Torres Strait Islander people, are overrepresented amongst patients with cirrh…
View article: The Patient’s Perspective in Cirrhosis: Unmet Supportive Care Needs Differ by Disease Severity, Etiology, and Age
The Patient’s Perspective in Cirrhosis: Unmet Supportive Care Needs Differ by Disease Severity, Etiology, and Age Open
Patients with cirrhosis have significant physical, psychological, and practical needs. We documented patients’ perceived need for support with these issues and the differences with increasing liver disease severity, etiology, and age. Usin…
View article: Assessment of health‐related quality of life and health utilities in Australian patients with cirrhosis
Assessment of health‐related quality of life and health utilities in Australian patients with cirrhosis Open
Background and Aim Health‐related quality‐of‐life measurements are important to understand lived experiences of patients who have cirrhosis. These measures also inform economic evaluations by modelling quality‐adjusted life years (QALYs). …
View article: Efficacy and Safety of Sofosbuvir/Velpatasvir/Voxilaprevir for Hepatitis C Virus (HCV) NS5A-Inhibitor Experienced Patients With Difficult to Cure Characteristics
Efficacy and Safety of Sofosbuvir/Velpatasvir/Voxilaprevir for Hepatitis C Virus (HCV) NS5A-Inhibitor Experienced Patients With Difficult to Cure Characteristics Open
Background In clinical trials, hepatitis C virus (HCV) salvage treatment with sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) achieved an SVR12 rate of >95% in NS5A-experienced participants. Lower SVR12 rates have been reported in rea…
View article: Effectiveness of patient‐oriented education and medication management intervention in people with decompensated cirrhosis
Effectiveness of patient‐oriented education and medication management intervention in people with decompensated cirrhosis Open
People with chronic disease often have poor comprehension of their disease and medications, which can negatively affect health outcomes. In a randomised‐controlled trial, we found that patients with decompensated cirrhosis who received a p…
View article: Stereotactic radiotherapy for hepatocellular carcinoma: Expanding the multidisciplinary armamentarium
Stereotactic radiotherapy for hepatocellular carcinoma: Expanding the multidisciplinary armamentarium Open
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the third most common cause of cancer‐related death. Long‐term prognosis remains poor with treatment options frequently limited by advanced tumor stage, tumor…
View article: <p>Development and Evaluation of the Supportive Needs Assessment Tool for Cirrhosis (SNAC)</p>
Development and Evaluation of the Supportive Needs Assessment Tool for Cirrhosis (SNAC) Open
These data provide initial evidence for the validity and reliability of the SNAC, an instrument designed to measure type and amount of perceived unmet practical and psychological needs of people diagnosed with cirrhosis.