Katherine W. Saylor
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Biomedical Researchers' Perceptions of the NIH's Sex as a Biological Variable Policy for Animal Research: Results from a U.S. National Survey Open
Background: In 2015, the National Institutes of Health (NIH) established a policy on sex as a biological variable (SABV) in an effort to address the overrepresentation of men and male animals in biomedical research and the lack of attentio…
Health State Utility Values: The Implications of Patient versus Community Ratings in Assessing the Value of Care Open
Background Health-state utility values (HSUVs) are key inputs into cost-utility analyses. There is debate over whether they are best derived from the community or patients, with concerns raised that community-derived preferences may devalu…
Is Enhancement the Price of Prevention in Human Gene Editing? Open
New gene-editing tools challenge conventional policy proscriptions of research aimed at either human germline gene editing or human enhancement by potentially lowering technical barriers to both kinds of intervention. Some recent gene-edit…
View article: Correction: Foss et al. The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation. J. Pers. Med. 2022, 12, 692
Correction: Foss et al. The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation. J. Pers. Med. 2022, 12, 692 Open
There was an error in the original publication [...].
Attitudes Toward Genetics and Genetic Testing Among Participants in the Jackson and Framingham Heart Studies Open
Genetic analysis has become integral to many large cohort studies. However, little is known about longitudinal cohort study participants' attitudes toward genetics and genetic testing. We analyzed data from a survey of participants in the …
View article: The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation
The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation Open
PURPOSE: Advances in clinical genomic sequencing capabilities, including reduced costs and knowledge gains, have bolstered the consideration of genomic screening in healthy adult populations. Yet, little is known about the existing landsca…
View article: Implementation Science Can Do Even More for Translational Ethics
Implementation Science Can Do Even More for Translational Ethics Open
In their paper “The ‘Ought-Is’ Problem,” Sisk and colleagues present a strong case for translating bioethics research and show how implementation science can help identify requirements and barriers for bioethics findings to be incorporated…
Genetic Testing and Other Healthcare Use by Black and White Individuals in a Genomic Sequencing Study Open
INTRODUCTION: Early adopters play a critical role in the diffusion of medical innovations by spreading awareness, increasing acceptability, and driving demand. Understanding the role of race in the context of other characteristics of poten…
View article: Correction: Foss et al. The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation. J. Pers. Med. 2022, 12, 692
Correction: Foss et al. The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation. J. Pers. Med. 2022, 12, 692 Open
There was an error in the original publication [...]
Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions Open
Precision public health holds promise to improve disease prevention and health promotion strategies, allowing the right intervention to be delivered to the right population at the right time. Growing concerns underscore the potential for p…
Enhancing social value considerations in prioritising publicly funded biomedical research: the vital role of peer review Open
The main goal of publicly funded biomedical research is to generate social value through the creation and application of knowledge that can improve the well-being of current and future people. Prioritising research with the greatest potent…
Genetic Testing and Other Healthcare Use by Black and White Individuals in a Genomic Sequencing Study Open
Introduction: Early adopters play a critical role in the diffusion of medical innovations by spreading awareness, increasing acceptability, and driving demand. Understanding the role of race in the context of other characteristics of poten…
View article: Public Interest in Population Genetic Screening for Cancer Risk
Public Interest in Population Genetic Screening for Cancer Risk Open
An emerging role for DNA sequencing is to identify people at risk for an inherited cancer syndrome in order to prevent or ameliorate the manifestation of symptoms. Two cancer syndromes, Hereditary Breast and Ovarian Cancer and Lynch Syndro…
View article: Public Interest in Population Genetic Screening for Cancer Risk
Public Interest in Population Genetic Screening for Cancer Risk Open
An emerging role for DNA sequencing is to identify people at risk for an inherited cancer syndrome in order to prevent or ameliorate the manifestation of symptoms. Two cancer syndromes, Hereditary Breast and Ovarian Cancer and Lynch Syndro…
View article: The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation
The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation Open
Purpose: Advances in clinical genomic sequencing capabilities, including reduced costs and knowledge gains, have bolstered the consideration of genomic screening in healthy adult populations. Yet, little is known about the existing landsca…
Biomedical Researchers' Perceptions of the NIH's Sex as a Biological Variable Policy for Animal Research: Results from a U.S. National Survey Open
Background: In 2015, the National Institutes of Health (NIH) established a policy on sex as a biological variable (SABV) in an effort to address the overrepresentation of men and male animals in biomedical research and the lack of attentio…
Implementation Science Can Do Even More for Translational Ethics Open
This article refers to:The “Ought-Is” Problem: An Implementation Science Framework for Translating Ethical Norms Into Practice
Four Faces of Fair Subject Selection Open
Although the principle of fair subject selection is a widely recognized requirement of ethical clinical research, it often yields conflicting imperatives, thus raising major ethical dilemmas regarding participant selection. In this paper, …
Attitudes Toward Genetics and Genetic Testing Among Participants in the Jackson and Framingham Heart Studies Open
Genetic analysis has become integral to many large cohort studies. However, little is known about longitudinal cohort study participants’ attitudes toward genetics and genetic testing. We analyzed data from a survey of participants in the …