Kathleen A. Linder
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View article: P-331. Patient Perspectives Regarding the Use of Contact Precautions for Methicillin-Resistant <i>Staphylococcus aureus</i> in a VA Acute Care Hospital
P-331. Patient Perspectives Regarding the Use of Contact Precautions for Methicillin-Resistant <i>Staphylococcus aureus</i> in a VA Acute Care Hospital Open
Background The optimal approach to using contact precautions for patients known to be colonized or infected with MRSA remains unclear despite knowledge that transmission risk varies by healthcare personnel role and care activity being perf…
View article: P-2302. Efficacy of Universal vs Targeted Antifungal Prophylaxis for the Prevention of Invasive Fungal Infections after Lung Transplant
P-2302. Efficacy of Universal vs Targeted Antifungal Prophylaxis for the Prevention of Invasive Fungal Infections after Lung Transplant Open
Background IFI are associated with high morbidity and mortality among LTx patients (pt). Preventive strategies are commonly used, but the optimal AP approach is unclear. Over the last 10 years, our LTx program has transitioned from univers…
View article: P-322. Transmission of Methicillin-Resistant <i>Staphylococcus aureus</i> to Healthcare Personnel Gloves and Gowns: a Cohort Study of VA Hospitals in 5 States
P-322. Transmission of Methicillin-Resistant <i>Staphylococcus aureus</i> to Healthcare Personnel Gloves and Gowns: a Cohort Study of VA Hospitals in 5 States Open
Background The aim of this study was to determine the rate of MRSA transmission to healthcare personnel (HCP) gloves and gown and to determine which patient care interactions and HCP roles are associated with greater transmission of MRSA. …
View article: P-951. Delphi Study of a Fungal Curriculum for Infectious Diseases Fellows
P-951. Delphi Study of a Fungal Curriculum for Infectious Diseases Fellows Open
Background Infectious Diseases (ID) clinicians must be proficient in diagnosis and management of fungal diseases. Though certain fungal diseases have geographic distributions, those distributions are shifting, and ID fellows need to be pre…
View article: Influenza Vaccination Requirements for Health Care Personnel in US Hospitals
Influenza Vaccination Requirements for Health Care Personnel in US Hospitals Open
This survey study assesses changes from 2017 to 2021 in self-reported annual influenza vaccination among workers in nonfederal and Veterans Affairs hospitals.
View article: ICE volume 44 issue 12 Cover and Front matter
ICE volume 44 issue 12 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Comparing practices to prevent infectious diseases transmission among Veterans Affairs and Nonveterans Affairs hospitals: Results from a national survey in the United States
Comparing practices to prevent infectious diseases transmission among Veterans Affairs and Nonveterans Affairs hospitals: Results from a national survey in the United States Open
Our national cross-sectional survey of United States hospitals found greater implementation of contact precautions for multidrug-resistant organisms and a higher percentage reporting the use of supplemental no-touch disinfection devices am…
View article: RSV Infection in Older Adults
RSV Infection in Older Adults Open
This JAMA Patient Page describes respiratory syncytial virus (RSV) and its symptoms, risk factors, and preventive measures.
View article: Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-free DNA Testing in the Management of Patients With Suspected Infectious Diseases
Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-free DNA Testing in the Management of Patients With Suspected Infectious Diseases Open
Metagenomic next-generation sequencing (mNGS) of cell-free DNA is an emerging modality for the diagnosis of infectious diseases, but studies on its clinical utility are limited. We conducted a retrospective single-center study including al…
View article: What US hospitals are doing to prevent common device-associated infections during the coronavirus disease 2019 (COVID-19) pandemic: Results from a national survey in the United States
What US hospitals are doing to prevent common device-associated infections during the coronavirus disease 2019 (COVID-19) pandemic: Results from a national survey in the United States Open
Objective: The ways that device-associated infection prevention practices changed during the coronavirus disease 2019 (COVID-19) pandemic remain unknown. We collected data mid-pandemic to assess the use of several infection prevention prac…
View article: Blastomycosis: A Review of Mycological and Clinical Aspects
Blastomycosis: A Review of Mycological and Clinical Aspects Open
Blastomycosis is caused by a thermally dimorphic fungus that thrives in moist acidic soil. Blastomyces dermatitidis is the species responsible for most infections in North America and is especially common in areas around the Great Lakes, t…
View article: 354. Invasive fungal disease in patients with severe COVID-19 infection at a midwestern academic medical center
354. Invasive fungal disease in patients with severe COVID-19 infection at a midwestern academic medical center Open
Background Invasive fungal diseases (IFD) have been described in patients (pts) with severe coronavirus disease 2019 (COVID), albeit with geographic variability in rates. Methods We performed a retrospective study to determine rates of & r…
View article: SARS-CoV-2 Anti-Spike IgG Antibody and ACE2 Receptor Binding Inhibition Levels among Breakthrough Stage Veteran Patients
SARS-CoV-2 Anti-Spike IgG Antibody and ACE2 Receptor Binding Inhibition Levels among Breakthrough Stage Veteran Patients Open
Currently, clinicians have no guidance for the serologic assessment of SARS-Cov-2 postvaccination status regarding protection and risk of infection. Vaccination and boosters are administered blindly without evaluation of need or outcome at…
View article: Infectious complications after second allogeneic hematopoietic cell transplant in adult patients with hematological malignancies
Infectious complications after second allogeneic hematopoietic cell transplant in adult patients with hematological malignancies Open
View article: Infectious complications after second allogeneic hematopoietic cell transplant in adult patients with hematological malignancies
Infectious complications after second allogeneic hematopoietic cell transplant in adult patients with hematological malignancies Open
this is the data based we used to answer the question of infectious complications after second allogenic stem cell transplant
View article: Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Histoplasmosis
Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Histoplasmosis Open
Hemophagocytic lymphohistiocytosis is a syndrome of immune dysregulation that can lead to an overwhelming inflammatory state. In this case series, we describe 3 cases in which disseminated Histoplasma capsulatum infection caused hemophagoc…
View article: Invasive Fungal Disease in Patients with Newly Diagnosed Acute Myeloid Leukemia
Invasive Fungal Disease in Patients with Newly Diagnosed Acute Myeloid Leukemia Open
This single-center retrospective study of invasive fungal disease (IFD) enrolled 251 adult patients undergoing induction chemotherapy for newly diagnosed acute myeloid leukemia (AML) from 2014–2019. Patients had primary AML (n = 148, 59%);…
View article: Letermovir treatment of cytomegalovirus infection or disease in solid organ and hematopoietic cell transplant recipients
Letermovir treatment of cytomegalovirus infection or disease in solid organ and hematopoietic cell transplant recipients Open
Background Few options are available for cytomegalovirus (CMV) treatment in transplant recipients resistant, refractory, or intolerant to approved agents. Letermovir (LET) is approved for prophylaxis in hematopoietic cell transplant (HCT) …
View article: COVID-19-Associated Pulmonary Aspergillosis at an Academic Medical Center in the Midwestern United States
COVID-19-Associated Pulmonary Aspergillosis at an Academic Medical Center in the Midwestern United States Open
View article: ‘Case of the Month’ from University of Michigan, Ann Arbor, MI, USA: emphysematous pyelonephritis following ureteroscopy in a solitary kidney
‘Case of the Month’ from University of Michigan, Ann Arbor, MI, USA: emphysematous pyelonephritis following ureteroscopy in a solitary kidney Open
Peer Reviewed
View article: Current and New Perspectives in the Diagnosis of Blastomycosis and Histoplasmosis
Current and New Perspectives in the Diagnosis of Blastomycosis and Histoplasmosis Open
The diagnosis of blastomycosis and histoplasmosis can be difficult for clinicians who rarely see infections caused by these environmentally restricted dimorphic fungi. Historically, the diagnosis of blastomycosis has been established by cu…
View article: Performance of Aspergillus Galactomannan Lateral Flow Assay on Bronchoalveolar Lavage Fluid for the Diagnosis of Invasive Pulmonary Aspergillosis
Performance of Aspergillus Galactomannan Lateral Flow Assay on Bronchoalveolar Lavage Fluid for the Diagnosis of Invasive Pulmonary Aspergillosis Open
Background: Several newly developed biomarker tests for invasive pulmonary aspergillosis (IPA) have been developed, including the IMMY Aspergillus galactomannan lateral flow assay (Aspergillus GM-LFA) evaluated in this study. Methods: Twen…
View article: 1150. Breakthrough Invasive Fungal Disease (IFD) in Patients with Acute Myeloid Leukemia (AML)
1150. Breakthrough Invasive Fungal Disease (IFD) in Patients with Acute Myeloid Leukemia (AML) Open
Background Despite the use of antifungal prophylaxis, IFD remains a serious complication of AML causing extensive morbidity and mortality. This study seeks to clarify our experience with breakthrough infections in patients with AML. Method…
View article: Diagnostic Performance of Bronchoalveolar Lavage (1,3)-β-d-Glucan Assay for Pneumocystis jirovecii Pneumonia
Diagnostic Performance of Bronchoalveolar Lavage (1,3)-β-d-Glucan Assay for Pneumocystis jirovecii Pneumonia Open
We evaluated the performance of the (1,3)-β-d-glucan (BDG) assay on bronchoalveolar lavage fluid (BALF) as a possible aid to the diagnosis of Pneumocystis jirovecii pneumonia. BALF samples from 18 patients with well-characterized proven, p…
View article: 1077. Infectious complications after second allogeneic hematopoietic cell transplant (allo-HCT) in adult patients with hematological malignancies
1077. Infectious complications after second allogeneic hematopoietic cell transplant (allo-HCT) in adult patients with hematological malignancies Open
Background A 2nd allo-HCT is received by some adults after relapse of their underlying malignancy, development of a second malignancy, or graft failure. Few studies have reported on infectious complications in adults given a 2nd HCT Method…
View article: Evaluation of targeted versus universal prophylaxis for the prevention of invasive fungal infections following lung transplantation
Evaluation of targeted versus universal prophylaxis for the prevention of invasive fungal infections following lung transplantation Open
Background Antifungal prophylaxis to prevent invasive fungal infections (IFI) is widely used following lung transplantation, but the optimal strategy remains unclear. We compared universal with targeted antifungal prophylaxis for effective…
View article: Clinical application of <i>Aspergillus</i> lateral flow device in bronchoalveolar lavage fluid of patients with classic risk factors for invasive pulmonary aspergillosis
Clinical application of <i>Aspergillus</i> lateral flow device in bronchoalveolar lavage fluid of patients with classic risk factors for invasive pulmonary aspergillosis Open
Summary Background The diagnosis of invasive pulmonary aspergillosis (IPA) remains challenging. We evaluated the performance characteristics of a newly formatted Aspergillus lateral flow test, Asp LFD, in bronchoalveolar lavage (BAL) fluid…
View article: 1736. Evaluation of Targeted vs. Universal Antifungal Prophylaxis (AP) for Invasive Fungal Infections (IFI) After Lung Transplant (LTx)
1736. Evaluation of Targeted vs. Universal Antifungal Prophylaxis (AP) for Invasive Fungal Infections (IFI) After Lung Transplant (LTx) Open
Background LTx patients (pt) are at increased risk for IFI. Systemic AP is widely used, but the optimal strategy remains unclear. Our LTx program changed from universal to targeted AP in July 2016; we compared outcomes between the 2 strate…
View article: Treatment Failure of Isavuconazole in a Patient with Cryptococcosis
Treatment Failure of Isavuconazole in a Patient with Cryptococcosis Open
View article: Histoplasmosis: Epidemiology, Diagnosis, and Clinical Manifestations
Histoplasmosis: Epidemiology, Diagnosis, and Clinical Manifestations Open