Kathleen E. Corey
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View article: MON-696 Obesity and Metabolic Comorbidities in Young Adults with Perinatal HIV Exposure Without Infection
MON-696 Obesity and Metabolic Comorbidities in Young Adults with Perinatal HIV Exposure Without Infection Open
Disclosure: N. Chahal: None. A.K. Arpante: None. J.E. Johnson: None. C.A. Dash: None. M.W. Ockene: None. I. Zheng: None. A. Boutin: None. H. Lee: None. K.E. Corey: None. T.L. Stanley: None. S.K. Grinspoon: None. L.T. Fourman: None. Backgro…
View article: Real‐World Assessment of Liver Corrected T1 and Magnetic Resonance Elastography in Predicting Liver Disease Progression
Real‐World Assessment of Liver Corrected T1 and Magnetic Resonance Elastography in Predicting Liver Disease Progression Open
Background Clinical guidelines emphasise identifying patients at risk of chronic liver disease progression. To avoid biopsy drawbacks, noninvasive imaging tests (NITs) have become part of standard‐of‐care. We assessed the real‐world clinic…
View article: Circulating fibroblast growth factor 21 and growth differentiation factor 15 are associated with severity of hepatic steatosis in people with <scp>HIV</scp>
Circulating fibroblast growth factor 21 and growth differentiation factor 15 are associated with severity of hepatic steatosis in people with <span>HIV</span> Open
Background Hepatic steatosis poses a significant health burden in people with HIV. Fibroblast growth factor 21 (FGF21) production from the liver regulates glucose metabolism. Higher serum levels of FGF21 are associated with hepatic steatos…
View article: Supplementary Table S8 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S8 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S8: Random Forest classifier analysis of plasma metabolite profiles: HCC cases compared to all controls (derivation cohort)
View article: Data from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Data from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Despite increasing incidence of hepatocellular carcinoma (HCC) in vulnerable populations, accurate early detection tools are lacking. We aimed to investigate the associations between prediagnostic plasma metabolites and incident HCC in a d…
View article: Supplementary Table S3 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S3 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S3: Metabolite Set Enrichment Analysis in HCC Cases Compared to Controls with Cirrhosis
View article: Supplementary Table S2 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S2 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S2: Subgroup Analyses: Associations of Individual Plasma Metabolites with Risk of Hepatocellular Carcinoma in Multivariable-Adjusted Unconditional Logistic Regression Models in HCC Cases vs. Controls with Cirrhosis
View article: Supplementary Figure S1 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Figure S1 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Figure S1: Metabolite set enrichment analysis displaying the top 25 metabolic pathways enriched in HCC cases relative to all controls
View article: Supplementary Table S7 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S7 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S7: Metabolite Set Enrichment Analysis in HCC Cases Compared to All Controls
View article: Supplementary Figure S2 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Figure S2 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Figure S2: Performance of Random Forest-derived pre-diagnostic plasma metabolite signatures and covariate-based signatures in predicting HCC among HCC cases and all controls
View article: Supplementary Table S6 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S6 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S6: Associations of Individual Plasma Metabolites with Risk of Hepatocellular Carcinoma in Multivariable-Adjusted Unconditional Logistic Regression Models in HCC Cases versus All Controls
View article: Supplementary Table S1 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S1 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S1: Baseline characteristics of the derivation cohort comprised of participants with HCC, matched controls without cirrhosis, and unmatched controls with cirrhosis who underwent plasma metabolomics profiling
View article: Supplementary Table S4 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S4 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S4: Random Forest Classifier Analysis for Importance of Individual Plasma Metabolites and Clinical Covariates for Prediction of Hepatocellular Carcinoma in HCC Cases compared to Controls with Cirrhosis
View article: Supplementary Table S5 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Supplementary Table S5 from Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Supplementary Table S5: Baseline characteristics of the validation cohort comprised of controls with cirrhosis matched to cases with cirrhosis and incident hepatocellular carcinoma
View article: Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis
Prediagnostic Plasma Metabolites Are Associated with Incident Hepatocellular Carcinoma: A Prospective Analysis Open
Despite increasing incidence of hepatocellular carcinoma (HCC) in vulnerable populations, accurate early detection tools are lacking. We aimed to investigate the associations between prediagnostic plasma metabolites and incident HCC in a d…
View article: Coronary Artery Disease and Major Adverse Cardiovascular Events in People With Hepatic Steatosis at Low Atherosclerotic Cardiovascular Disease Risk
Coronary Artery Disease and Major Adverse Cardiovascular Events in People With Hepatic Steatosis at Low Atherosclerotic Cardiovascular Disease Risk Open
Background Hepatic steatosis (HS) and 10‐year atherosclerotic cardiovascular disease (ASCVD) risk ≥ 7.5% are associated with increased risk for cardiovascular events. Aim To assess underlying coronary artery disease (CAD) and major adverse…
View article: Quantitative <scp>MRI</scp> for Monitoring Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Test–Retest Repeatability Study
Quantitative <span>MRI</span> for Monitoring Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Test–Retest Repeatability Study Open
Background Quantitative magnetic resonance imaging metrics iron‐corrected T1 (cT1) and liver fat from proton density fat‐fraction (PDFF) are both commonly used as noninvasive biomarkers for metabolic dysfunction‐associated steatohepatitis …
View article: Effects of Semaglutide on Muscle Structure and Function in the SLIM LIVER Study
Effects of Semaglutide on Muscle Structure and Function in the SLIM LIVER Study Open
Background Semaglutide is highly effective for decreasing weight. Concomitant loss of muscle mass often accompanies weight loss and may have consequences on muscle function. Methods This is a secondary analysis from the SLIM LIVER (Advanci…
View article: Aspirin for Metabolic Dysfunction–Associated Steatotic Liver Disease Without Cirrhosis
Aspirin for Metabolic Dysfunction–Associated Steatotic Liver Disease Without Cirrhosis Open
Importance Aspirin may reduce severity of metabolic dysfunction–associated steatotic liver disease (MASLD) and lower the incidence of end-stage liver disease and hepatocellular carcinoma, in patients with MASLD. However, the effect of aspi…
View article: Prevalence of steatotic liver disease, MASLD, MetALD and significant fibrosis in people with HIV in the United States
Prevalence of steatotic liver disease, MASLD, MetALD and significant fibrosis in people with HIV in the United States Open
Summary Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) has recently been proposed as a replacement term for NAFLD. Aims To assess the effects of this new nomenclature on the prevalence and distribution of diffe…
View article: Effect of combined tobacco use and type 2 diabetes mellitus on prevalent fibrosis in patients with MASLD
Effect of combined tobacco use and type 2 diabetes mellitus on prevalent fibrosis in patients with MASLD Open
Background: Several studies have investigated the independent effect of cigarette smoking or type 2 diabetes mellitus (T2DM) on MASLD. However, the interaction effect between tobacco consumption and T2DM on MASLD severity remains underexpl…
View article: Growth Hormone Administration Improves Nonalcoholic Fatty Liver Disease in Overweight/Obesity: A Randomized Trial
Growth Hormone Administration Improves Nonalcoholic Fatty Liver Disease in Overweight/Obesity: A Randomized Trial Open
Context Overweight and obesity are associated with relative growth hormone (GH) deficiency, which has been implicated in the development of nonalcoholic fatty liver disease (NAFLD). NAFLD is a progressive disease without effective treatmen…