Kathrin Marini
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View article: Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study
Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study Open
Background Preferences for risk disclosure in population‐based studies assessing Parkinson's disease (PD) risk have not been assessed so far. Objectives To examine preferences for risk disclosure in a subset of the European Healthy Brain A…
View article: The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease
The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease Open
Background PREDICT‐PD is a United Kingdom population‐based study aiming to stratify individuals for future Parkinson's disease (PD) using a risk algorithm. Methods A randomly selected, representative sample of participants in PREDICT‐PD we…
View article: Temporal Muscle Thickness Correlates with Sarcopenia in Parkinson’s Disease
Temporal Muscle Thickness Correlates with Sarcopenia in Parkinson’s Disease Open
Background: Sarcopenia is characterized by a progressive loss of muscle mass, strength, and function resulting in adverse health outcomes. Current assessment strategies are bothersome and means to simplify the diagnosis are an unmet medica…
View article: Eye Tracking in Patients with Parkinson’s Disease Treated with Nabilone–Results of a Phase II, Placebo-Controlled, Double-Blind, Parallel-Group Pilot Study
Eye Tracking in Patients with Parkinson’s Disease Treated with Nabilone–Results of a Phase II, Placebo-Controlled, Double-Blind, Parallel-Group Pilot Study Open
The topic of the therapeutic use of cannabinoids in Parkinson’s disease (PD) is broadly discussed and frequently comes up in the outpatient clinic. So far, there are only a few randomized clinical trials assessing the effects of cannabinoi…
View article: Application of the Updated Movement Disorder Society Criteria for Prodromal Parkinson's Disease to a Population‐Based 10‐Year Study
Application of the Updated Movement Disorder Society Criteria for Prodromal Parkinson's Disease to a Population‐Based 10‐Year Study Open
In 2015, a Task Force of the Movement Disorder Society (MDS) proposed evidence-based, probabilistic research diagnostic criteria for prodromal Parkinson's disease (PD).1 Studies that applied the criteria to existing longitudinal population…
View article: Rapid eye movement sleep behavior disorder and rapid eye movement sleep without atonia are more frequent in advanced versus early Parkinson’s disease
Rapid eye movement sleep behavior disorder and rapid eye movement sleep without atonia are more frequent in advanced versus early Parkinson’s disease Open
Study Objectives To evaluate macro sleep architecture and characterize rapid eye movement (REM) sleep without atonia (RWA) by using the SINBAR excessive electromyographic (EMG) montage including mentalis and upper extremity muscles in earl…
View article: Supplementary Material for: Associations of Gait Disorders and Recurrent Falls in Older People: A Prospective Population-Based Study
Supplementary Material for: Associations of Gait Disorders and Recurrent Falls in Older People: A Prospective Population-Based Study Open
Background: Recurrent falls represent a major source of serious adverse health outcomes in the general older population. Gait impairment has been linked to recurrent falls, but there are only limited long-term data on this association. Obj…
View article: Non‐Motor Symptoms in Parkinson's Disease are Reduced by Nabilone
Non‐Motor Symptoms in Parkinson's Disease are Reduced by Nabilone Open
Objective The objective of this study was to assess the efficacy and safety of nabilone, a synthetic tetrahydrocannabinol analogue, as a treatment for non‐motor symptoms (NMS) in Parkinson's disease (PD). Methods This was a phase II placeb…
View article: Application of a Simple Parkinson's Disease Risk Score in a Longitudinal <scp>Population‐Based</scp> Cohort
Application of a Simple Parkinson's Disease Risk Score in a Longitudinal <span>Population‐Based</span> Cohort Open
Background Identifying individuals at risk of developing Parkinson's disease (PD) is critical to define target populations for future neuroprotective trials. Objective The objective of this study was to apply the PREDICT‐PD algorithm of ri…
View article: New hopes for disease modification in Parkinson's Disease
New hopes for disease modification in Parkinson's Disease Open
To date, despite numerous clinical trials, no intervention has been demonstrated to modify the progression of Parkinson's disease (PD). However, over the past decades encouraging progress has been made towards a better understanding of mol…