Kathrin Ohla
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View article: Effects of one year of extreme isolation in Antarctica on olfactory and gustatory functions
Effects of one year of extreme isolation in Antarctica on olfactory and gustatory functions Open
Taste and smell are critical for food intake and maintaining adequate energy balance, particularly in isolated, confined, and extreme (ICE) environments. Hypoxic conditions, low humidity, and limited chemosensory exposure at Concordia Stat…
View article: Missing what's right under your nose: Failed appetitive and aversive audio-olfactory conditioning in humans
Missing what's right under your nose: Failed appetitive and aversive audio-olfactory conditioning in humans Open
The comparison of physiological mechanisms underlying appetitive and aversive conditioning is often challenging due to the involvement of stimuli from different modalities with potentially disparate effective mechanisms (e.g., pain stimuli…
View article: Post-vaccination outcomes in COVID-19-associated chemosensory dysfunction
Post-vaccination outcomes in COVID-19-associated chemosensory dysfunction Open
Olfactory and taste dysfunction is a common symptom of COVID-19 and post-acute COVID-19 syndrome. Although vaccines have been suggested to influence chemosensory function both positively and negatively, data remain limited. This global sur…
View article: Missing what’s right under your nose: failed appetitive and aversive audio-olfactory conditioning in humans
Missing what’s right under your nose: failed appetitive and aversive audio-olfactory conditioning in humans Open
The comparison of physiological mechanisms underlying appetitive and aversive conditioning is often challenging due to the involvement of stimuli from different modalities with potentially disparate effective mechanisms (e.g., pain stimuli…
View article: Single-neuron representations of odours in the human brain
Single-neuron representations of odours in the human brain Open
View article: Differences in Discounting Behavior and Brain Responses for Food and Money Reward
Differences in Discounting Behavior and Brain Responses for Food and Money Reward Open
Most neuroeconomic research seeks to understand how value influences decision-making. The influence of reward type is less well understood. We used functional magnetic resonance imaging (fMRI) to investigate delay discounting of primary (i…
View article: Text-based predictions of COVID-19 diagnosis from self-reported chemosensory descriptions
Text-based predictions of COVID-19 diagnosis from self-reported chemosensory descriptions Open
Background There is a prevailing view that humans’ capacity to use language to characterize sensations like odors or tastes is poor, providing an unreliable source of information. Methods Here, we developed a machine learning method based …
View article: Covid-19 affects taste independently of smell: results from a combined chemosensory home test and online survey from a global cohort (N=10,953)
Covid-19 affects taste independently of smell: results from a combined chemosensory home test and online survey from a global cohort (N=10,953) Open
People often confuse smell loss with taste loss, so it is unclear how much gustatory function is reduced in patients self-reporting taste loss. Our pre-registered cross-sectional study design included an online survey in 12 languages with …
View article: Covid-19 affects taste independent of taste–smell confusions: results from a combined chemosensory home test and online survey from a large global cohort
Covid-19 affects taste independent of taste–smell confusions: results from a combined chemosensory home test and online survey from a large global cohort Open
People often confuse smell loss with taste loss, so it is unclear how much gustatory function is reduced in patients self-reporting taste loss. Our pre-registered cross-sectional study design included an online survey in 12 languages with …
View article: Nutrition claims influence expectations about food attributes, attenuate activity in reward‐associated brain regions during tasting, but do not impact pleasantness
Nutrition claims influence expectations about food attributes, attenuate activity in reward‐associated brain regions during tasting, but do not impact pleasantness Open
Introduction Nutrition claims are one of the most common tools used to improve food decisions. Previous research has shown that nutrition claims impact expectations; however, their effects on perceived pleasantness, valuation, and their ne…
View article: Taste It! 7-Day Exposure to a Protein-Enriched Milk Drink Increases Its Smell, Taste, and Flavor Familiarity and Facilitates Acquisition of Taste Familiarity of a Novel Protein Drink
Taste It! 7-Day Exposure to a Protein-Enriched Milk Drink Increases Its Smell, Taste, and Flavor Familiarity and Facilitates Acquisition of Taste Familiarity of a Novel Protein Drink Open
Novel and reformulated food, in particular protein-enhanced drinks, provide an important strategy to promote healthy eating. Despite their availability, protein-enriched foods are not widely accepted, likely owing to their unexpected “tast…
View article: Taste It! 7-Day Exposure to a Protein-Enriched Milk Drink Increases Its Smell, Taste, and Flavor Familiarity and Facilitates Acquisition of Taste Familiarity of a Novel Protein Drink
Taste It! 7-Day Exposure to a Protein-Enriched Milk Drink Increases Its Smell, Taste, and Flavor Familiarity and Facilitates Acquisition of Taste Familiarity of a Novel Protein Drink Open
Epidemiological studies suggest that the average dietary protein intake is insufficient to maintain muscle mass as we age. Despite their availability, protein-enriched foods are not widely accepted, likely owing to their unexpected “taste”…
View article: The capacity and organization of gustatory working memory
The capacity and organization of gustatory working memory Open
View article: A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss
A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss Open
Background: Sudden smell loss is a specific early symptom of COVID-19, which, prior to the emergence of Omicron, had estimated prevalence of ~40% to 75%. Chemosensory impairments affect physical and mental health, and dietary behavior. Thu…
View article: Associations between Taste and Smell Sensitivity, Preference and Quality of Life in Healthy Aging—The NutriAct Family Study Examinations (NFSE) Cohort
Associations between Taste and Smell Sensitivity, Preference and Quality of Life in Healthy Aging—The NutriAct Family Study Examinations (NFSE) Cohort Open
Taste and smell function decline with age, with robust impairment in the very old. Much less is known about taste and smell function in young and middle aged. We investigated taste and smell sensitivity via thresholds in a sub-sample of th…
View article: Associations between Taste and Smell Sensitivity, Preference, and Quality of Life in Healthy Aging - The NutriAct Family Study Examinations (NFSE) Cohort
Associations between Taste and Smell Sensitivity, Preference, and Quality of Life in Healthy Aging - The NutriAct Family Study Examinations (NFSE) Cohort Open
Taste and smell function decline with age, with robust impairment in the very old. Much less is known about taste and smell function in young and middle old. We investigated taste and smell sensitivity via thresholds in a sub-sample of the…
View article: Leveraging machine learning and self-administered tests to predict COVID-19: An olfactory and gustatory dysfunction assessment through crowd-sourced data in India
Leveraging machine learning and self-administered tests to predict COVID-19: An olfactory and gustatory dysfunction assessment through crowd-sourced data in India Open
It has been established that smell and taste loss are frequent symptoms during COVID-19 onset. Most evidence stems from medical exams or self-reports. The latter is particularly confounded by the common confusion of smell and taste. Here, …
View article: Assessing the extent and timing of chemosensory impairments during COVID-19 pandemic
Assessing the extent and timing of chemosensory impairments during COVID-19 pandemic Open
View article: Increasing incidence of parosmia and phantosmia in patients recovering from COVID-19 smell loss
Increasing incidence of parosmia and phantosmia in patients recovering from COVID-19 smell loss Open
Importance Sudden smell loss is a specific early symptom of COVID-19, with an estimated prevalence of ~40% to 75%. Smell impairment affects physical and mental health, and dietary behavior. Thus, it is critical to understand the rate and t…
View article: From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic
From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic Open
Chemosensory impairments have been established as a specific indicator of COVID-19. They affect most patients and may persist long past the resolution of respiratory symptoms, representing an unprecedented medical challenge. Since the SARS…
View article: Durable memories and efficient neural coding through mnemonic training using the method of loci
Durable memories and efficient neural coding through mnemonic training using the method of loci Open
Mnemonic training boosts long-lasting memories, supported by optimized brain processing and consolidation.
View article: The Capacity and Organization of Gustatory Working Memory
The Capacity and Organization of Gustatory Working Memory Open
Remembering a particular taste is crucial in food intake and associative learning. We investigated whether taste can be dynamically encoded, maintained, and retrieved on short time-scales consistent with working memory (WM). We used novel …
View article: Recent Smell Loss Is the Best Predictor of COVID-19 Among Individuals With Recent Respiratory Symptoms
Recent Smell Loss Is the Best Predictor of COVID-19 Among Individuals With Recent Respiratory Symptoms Open
In a preregistered, cross-sectional study, we investigated whether olfactory loss is a reliable predictor of COVID-19 using a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory il…
View article: Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine
Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine Open
View article: The best COVID-19 predictor is recent smell loss: a cross-sectional study
The best COVID-19 predictor is recent smell loss: a cross-sectional study Open
Background COVID-19 has heterogeneous manifestations, though one of the most common symptoms is a sudden loss of smell (anosmia or hyposmia). We investigated whether olfactory loss is a reliable predictor of COVID-19. Methods This preregis…
View article: More than smell – COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
More than smell – COVID-19 is associated with severe impairment of smell, taste, and chemesthesis Open
View article: More Than Smell—COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis
More Than Smell—COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis Open
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments, such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored ch…
View article: More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis Open
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored che…
View article: Durable memories and efficient neural coding through mnemonic training using the method of loci
Durable memories and efficient neural coding through mnemonic training using the method of loci Open
Mnemonic techniques, such as the method of loci, can powerfully boost memory. Here, we compared memory athletes ranked among the world’s top 50 in memory sports to mnemonics-naïve controls. In a second study, participants completed a six-w…
View article: Non-invasive recording from the human olfactory bulb
Non-invasive recording from the human olfactory bulb Open
Current non-invasive neuroimaging methods can assess neural activity in all areas of the human brain but the olfactory bulb (OB). The OB has been suggested to fulfill a role comparable to that of V1 and the thalamus in the visual system an…