Kathryn V. Dalrymple
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View article: A pilot point-of-care kidney disease clinic in primary care to pharmacologically optimise people with chronic kidney disease (PROTECT KIDNEY)
A pilot point-of-care kidney disease clinic in primary care to pharmacologically optimise people with chronic kidney disease (PROTECT KIDNEY) Open
Background Chronic kidney disease (CKD) is increasing in prevalence and is associated with substantial morbidity and mortality. Early initiation of cardiorenal protective medications is recommended to improve outcomes. Barriers to implemen…
View article: #361 A southeast London primary care allied health professional led point-of-care kidney clinic to pharmacologically optimise people with chronic kidney disease (protect kidney)
#361 A southeast London primary care allied health professional led point-of-care kidney clinic to pharmacologically optimise people with chronic kidney disease (protect kidney) Open
Background and Aims A new generation of treatments for chronic kidney disease (CKD) have potential to significantly improve cardiovascular and renal outcomes. However, barriers to implementation include renal function monitoring after reni…
View article: #360 Renal function assessment with point of care creatinine and potassium in diverse populations (RAPID study): An interim analysis
#360 Renal function assessment with point of care creatinine and potassium in diverse populations (RAPID study): An interim analysis Open
Background and Aims Point-of-care (POC) testing enhances care through rapid turnaround times, instant-decision making and improving patient engagement. With rising incidence of chronic kidney disease (CKD), early diagnosis and timely manag…
View article: The effect of lifestyle intervention and depression symptoms on binge eating and relation of binge eating to gestational weight gain and child birth weight in the UPBEAT cohort of pregnant women living with obesity
The effect of lifestyle intervention and depression symptoms on binge eating and relation of binge eating to gestational weight gain and child birth weight in the UPBEAT cohort of pregnant women living with obesity Open
Binge eating is one of the most prevalent eating disorder behaviours in pregnancy, its risk factors and association with pregnancy-related outcomes has sparsely researched in this population. This study aimed to investigate: (hypothesis 1)…
View article: The relationship between virtual antenatal care and pregnancy outcomes in a diverse UK inner-city population: a group-based trajectory modeling approach using routine health records
The relationship between virtual antenatal care and pregnancy outcomes in a diverse UK inner-city population: a group-based trajectory modeling approach using routine health records Open
A higher proportion of virtual care contacts in antenatal care in the second or third trimesters was associated with a greater risk of adverse pregnancy outcomes.
View article: Metallomic profiles of pregnant women living with obesity in the UK: a secondary analysis of UPBEAT
Metallomic profiles of pregnant women living with obesity in the UK: a secondary analysis of UPBEAT Open
Characterization of serum metal element concentrations in pregnancy enables the elucidation of relationships with maternal-fetal and neonatal health. Metal elements in the blood serve as essential cofactors for enzymatic reactions and cont…
View article: Temporal trends in pregnancy outcomes during a health system shock: A retrospective longitudinal study
Temporal trends in pregnancy outcomes during a health system shock: A retrospective longitudinal study Open
To better understand reported COVID-19 pandemic effects on pregnancy, we examined temporal trends in pregnancy outcomes in a diverse population from South London, United Kingdom. We included 31,411 singleton pregnancies with complete regis…
View article: The impact of the COVID-19 pandemic on maternal healthcare costs: a time series analysis of pregnancies of multi-ethnic mothers in South London, United Kingdom
The impact of the COVID-19 pandemic on maternal healthcare costs: a time series analysis of pregnancies of multi-ethnic mothers in South London, United Kingdom Open
The pandemic was associated with temporary reductions in maternity costs due to lower healthcare utilisation. Ongoing, rising maternity costs were unchanged. The pandemic had differential effects on Black and Asian women compared with Whit…
View article: Associations between diet quality indices and psoriasis severity: results from the Asking People with Psoriasis about Lifestyle and Eating (APPLE) cross-sectional study. – CORRIGENDUM
Associations between diet quality indices and psoriasis severity: results from the Asking People with Psoriasis about Lifestyle and Eating (APPLE) cross-sectional study. – CORRIGENDUM Open
View article: The relationship between virtual antenatal care and pregnancy outcomes in a diverse UK inner-city population; A group-based trajectory modelling approach using routine health records
The relationship between virtual antenatal care and pregnancy outcomes in a diverse UK inner-city population; A group-based trajectory modelling approach using routine health records Open
Background The COVID-19 pandemic resulted in major maternity service reconfigurations, particularly an increase in virtual antenatal care (vANC). We aimed to explore the relationship between vANC trajectories over time and pregnancy outcom…
View article: Are psoriasis severity and comorbidities associated with diet quality? A cross-sectional analysis using UK Biobank
Are psoriasis severity and comorbidities associated with diet quality? A cross-sectional analysis using UK Biobank Open
Participants with psoriasis showed slightly better adherence to a Mediterranean-style diet but also consumed more processed meat, sodium, free sugars, and alcohol. Those with the most severe psoriasis or comorbidities had poorer diet quali…
View article: The Interactive Effect of Prenatal Vitamin D Status and Maternal Obesity on Birth Outcomes among US Black Women
The Interactive Effect of Prenatal Vitamin D Status and Maternal Obesity on Birth Outcomes among US Black Women Open
View article: The impact of the COVID-19 pandemic on maternal healthcare costs:a time series analysis of pregnancies of multi-ethnic mothers in South London, United Kingdom
The impact of the COVID-19 pandemic on maternal healthcare costs:a time series analysis of pregnancies of multi-ethnic mothers in South London, United Kingdom Open
Background: Due to the COVID-19 pandemic, maternity care reconfigurations disrupted in-person care, which shifted towards virtual care and self-monitoring. We assessed the impact of these changes on maternity service provision costs. Metho…
View article: Associations between diet quality indices and psoriasis severity: results from the Asking People with Psoriasis about Lifestyle and Eating (APPLE) cross-sectional study
Associations between diet quality indices and psoriasis severity: results from the Asking People with Psoriasis about Lifestyle and Eating (APPLE) cross-sectional study Open
Psoriasis is a chronic immune-inflammatory skin disease. Cross-sectional research examining diet quality indices in psoriasis has focused on the Mediterranean diet and is confined to Mediterranean populations, thereby lacking generalisabil…
View article: WCN25-1495 OBSERVATIONAL COHORT WITH EMBEDDED RANDOMISED CONTROLLED TRIALS TO STUDY PREGNANCY-ASSOCIATED PROGRESSION OF RENAL DISEASE - A FEASIBILITY STUDY OF DIETARY NITRATE (BEETROOT JUICE) TO PROTECT KIDNEY FUNCTION IN PREGNANT WOMEN WITH CHRONIC KIDNEY DISEASE.
WCN25-1495 OBSERVATIONAL COHORT WITH EMBEDDED RANDOMISED CONTROLLED TRIALS TO STUDY PREGNANCY-ASSOCIATED PROGRESSION OF RENAL DISEASE - A FEASIBILITY STUDY OF DIETARY NITRATE (BEETROOT JUICE) TO PROTECT KIDNEY FUNCTION IN PREGNANT WOMEN WITH CHRONIC KIDNEY DISEASE. Open
View article: The impact of the COVID-19 pandemic on maternal healthcare costs in a UK inner-city multi-ethnic population
The impact of the COVID-19 pandemic on maternal healthcare costs in a UK inner-city multi-ethnic population Open
Background: During the COVID-19 pandemic, maternity care reconfigurations disrupted in-person care, which shifted towards virtual care and self-monitoring. We assessed the impact of these changes on healthcare costs. Methods: Data from Oct…
View article: Associations between maternal diet, family eating habits and preschool children’s dietary patterns: insights from the UPBEAT trial
Associations between maternal diet, family eating habits and preschool children’s dietary patterns: insights from the UPBEAT trial Open
Unhealthy dietary patterns in childhood are directly linked to similar maternal patterns and family meal behaviours, such as television viewing and food rewards. These findings highlight targetable behaviours for public health intervention…
View article: Breastfeeding behaviours in women with obesity; associations with weight retention and the serum metabolome: a secondary analysis of UPBEAT
Breastfeeding behaviours in women with obesity; associations with weight retention and the serum metabolome: a secondary analysis of UPBEAT Open
View article: Vitamin D status of pregnant women with obesity in the UK and its association with pregnancy outcomes: a secondary analysis of the UK Pregnancies Better Eating and Activity Trial (UPBEAT) study
Vitamin D status of pregnant women with obesity in the UK and its association with pregnancy outcomes: a secondary analysis of the UK Pregnancies Better Eating and Activity Trial (UPBEAT) study Open
Prenatal vitamin D deficiency is widely reported and may affect perinatal outcomes. In this secondary analysis of the UK Pregnancies Better Eating and Activity Trial, we examined vitamin D status and its relationship with selected pregnanc…
View article: WCN24-1183 Assessing kidney function in pregnancy: gestation specific centile reference ranges for serum creatinine, urea, cystatin c and beta-2-microglobulin
WCN24-1183 Assessing kidney function in pregnancy: gestation specific centile reference ranges for serum creatinine, urea, cystatin c and beta-2-microglobulin Open
Deterioration in maternal kidney function is associated with adverse pregnancy outcomes and long-term morbidity and mortality for mother and baby. Lack of accurate assessment of kidney function, accounting for physiological adaptation acro…
View article: WCN24-2050 ESTABLISHING THE PREVALENCE OF ACUTE KIDNEY INJURY IN A HIGH-RISK OBSTETRIC COHORT IN A TERTIARY MATERNITY UNIT IN FREETOWN, SIERRA LEONE
WCN24-2050 ESTABLISHING THE PREVALENCE OF ACUTE KIDNEY INJURY IN A HIGH-RISK OBSTETRIC COHORT IN A TERTIARY MATERNITY UNIT IN FREETOWN, SIERRA LEONE Open
Haemorrhage, hypertension and sepsis cause 75% of maternal deaths in Sierra Leone, and globally, and commonly lead to Acute Kidney Injury, which is associated with high rates of maternal and fetal morbidity and mortality (6 to 52%). Most d…
View article: Interventions in preconception and pregnant women at risk of gestational diabetes; a systematic review and meta-analysis of randomised controlled trials
Interventions in preconception and pregnant women at risk of gestational diabetes; a systematic review and meta-analysis of randomised controlled trials Open
View article: Hypertension prevalence, coding and control in an urban primary care setting in the UK between 2014 and 2021
Hypertension prevalence, coding and control in an urban primary care setting in the UK between 2014 and 2021 Open
Objective: Hypertension is a leading preventable cause of mortality, yet high rates of undiagnosed and uncontrolled hypertension continue. The burden falls most heavily on some ethnic minorities and the socially deprived, with the COVID-19…
View article: Longitudinal dietary trajectories from pregnancy to 3 years post delivery in women with obesity: relationships with adiposity
Longitudinal dietary trajectories from pregnancy to 3 years post delivery in women with obesity: relationships with adiposity Open
Objective The study aim was to examine the relationships between longitudinal dietary trajectories from early pregnancy to 3 years post delivery and adiposity measures in women with obesity. Methods The diets of 1208 women with obesity in …
View article: Project20: maternity care mechanisms that improve access and engagement for women with social risk factors in the UK – a mixed-methods, realist evaluation
Project20: maternity care mechanisms that improve access and engagement for women with social risk factors in the UK – a mixed-methods, realist evaluation Open
Objectives To evaluate how women access and engage with different models of maternity care, whether specialist models improve access and engagement for women with social risk factors, and if so, how? Design Realist evaluation. Setting Two …
View article: Changing epidemiology of acute kidney injury in critically ill patients with COVID-19: a prospective cohort
Changing epidemiology of acute kidney injury in critically ill patients with COVID-19: a prospective cohort Open
Background Acute kidney injury (AKI) is common in critically ill patients with coronavirus disease-19 (COVID-19). We aimed to explore the changes in AKI epidemiology between the first and the second COVID wave in the United Kingdom (UK). M…
View article: Micronutrient supplementation interventions in preconception and pregnant women at increased risk of developing pre-eclampsia: a systematic review and meta-analysis
Micronutrient supplementation interventions in preconception and pregnant women at increased risk of developing pre-eclampsia: a systematic review and meta-analysis Open
View article: Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT
Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT Open
Background/Objectives Obesity in pregnancy has been associated with increased childhood cardiometabolic risk and reduced life expectancy. The UK UPBEAT multicentre randomised control trial was a lifestyle intervention of diet and physical …
View article: Evaluation and interpretation of latent class modelling strategies to characterise dietary trajectories across early life: a longitudinal study from the Southampton Women’s Survey
Evaluation and interpretation of latent class modelling strategies to characterise dietary trajectories across early life: a longitudinal study from the Southampton Women’s Survey Open
There is increasing interest in modelling longitudinal dietary data and classifying individuals into subgroups (latent classes) who follow similar trajectories over time. These trajectories could identify population groups and time points …
View article: Preventing and treating childhood overweight and obesity in children up to 5 years old: A systematic review by intervention setting
Preventing and treating childhood overweight and obesity in children up to 5 years old: A systematic review by intervention setting Open
The prevalence of childhood obesity is increasing worldwide with long‐term health consequences. Effective strategies to stem the rising childhood obesity rates are needed but systematic reviews of interventions have reported inconsistent e…