Kati Hellsten
YOU?
Author Swipe
View article: A reference list of neurotoxicants based on CLP harmonised classifications
A reference list of neurotoxicants based on CLP harmonised classifications Open
With the societal interest to decrease experimental animal testing for regulatory purposes, the need for reliable new approach methods (NAMs) has become evident. To ensure the continued safe use of chemicals, NAMs should perform ideally at…
View article: New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project
New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project Open
In the European regulatory context, rodent in vivo studies are the predominant source of neurotoxicity information. Although they form a cornerstone of neurotoxicological assessments, they are costly and the topic of ethical debate. While …
View article: GABAA receptor subunit-related neuroanatomical substrates for attenuation of anxiety
GABAA receptor subunit-related neuroanatomical substrates for attenuation of anxiety Open
GABAergic inhibition is crucial for regulation of neuronal excitability and hence for optimal function of the nervous system. The GABAA receptor forms a pentameric ligand-gated anion channel. The subunit combinations of the receptors defin…