Katie Compton
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View article: Genetic testing practices among specialist physicians who treat prostate cancer
Genetic testing practices among specialist physicians who treat prostate cancer Open
Introduction: In patients with prostate cancer (PCa), the identification of an alteration in genes associated with homologous recombination repair (HRR) has implications for prognostication, optimization of therapy, and familial risk mitig…
View article: Germline Testing and Somatic Tumor Testing for<i>BRCA1/2</i>Pathogenic Variants in Ovarian Cancer: What Is the Optimal Sequence of Testing?
Germline Testing and Somatic Tumor Testing for<i>BRCA1/2</i>Pathogenic Variants in Ovarian Cancer: What Is the Optimal Sequence of Testing? Open
PURPOSE In 2020, ASCO recommended that all women with epithelial ovarian cancer have germline testing for BRCA1/2 mutations, and those without a germline pathogenic variant (PV) should have somatic tumor testing to determine eligibility fo…
View article: “Game Changer”: Health Professionals’ Views on the Clinical Utility of Circulating Tumor DNA Testing in Hereditary Cancer Syndrome Management
“Game Changer”: Health Professionals’ Views on the Clinical Utility of Circulating Tumor DNA Testing in Hereditary Cancer Syndrome Management Open
Background We explored health professionals’ views on the utility of circulating tumor DNA (ctDNA) testing in hereditary cancer syndrome (HCS) management. Materials and Methods A qualitative interpretive description study was conducted, us…
View article: Integrating Tumor Sequencing Into Clinical Practice for Patients With Mismatch Repair-Deficient Lynch Syndrome Spectrum Cancers
Integrating Tumor Sequencing Into Clinical Practice for Patients With Mismatch Repair-Deficient Lynch Syndrome Spectrum Cancers Open
INTRODUCTION: Uninformative germline genetic testing presents a challenge to clinical management for patients suspected to have Lynch syndrome, a cancer predisposition syndrome caused by germline variants in the mismatch repair (MMR) genes…
View article: Use of Treatment-Focused Tumor Sequencing to Screen for Germline Cancer Predisposition
Use of Treatment-Focused Tumor Sequencing to Screen for Germline Cancer Predisposition Open
View article: Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System
Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System Open
New streamlined models for genetic counseling and genetic testing have recently been developed in response to increasing demand for cancer genetic services. To improve access and decrease wait times, we implemented an oncology clinic-based…