Katie Dennis
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View article: Hepatitis E Virus Infection in a Liver Transplant Recipient Presenting With Late‐Onset Acute Rejection and Treated With Ribavirin
Hepatitis E Virus Infection in a Liver Transplant Recipient Presenting With Late‐Onset Acute Rejection and Treated With Ribavirin Open
Hepatitis E virus (HEV) is increasingly recognized as a cause of allograft hepatitis in transplant recipients. Persistent HEV infection is often asymptomatic with nonspecific findings on liver biopsy, requiring high clinical awareness to o…
View article: Hyaluronan synthesis inhibition normalizes ethanol‐enhanced hepatic stellate cell activation
Hyaluronan synthesis inhibition normalizes ethanol‐enhanced hepatic stellate cell activation Open
Background Chronic ethanol overconsumption promotes alcohol‐associated liver disease (ALD), characterized by hepatocyte injury, inflammation, hepatic stellate cell (HSC) activation, and fibrosis. Hyaluronan (HA) concentration is greater in…
View article: Pyruvate Dehydrogenase Kinase 4 Deficiency Increases Tumorigenesis in a Murine Model of Bladder Cancer
Pyruvate Dehydrogenase Kinase 4 Deficiency Increases Tumorigenesis in a Murine Model of Bladder Cancer Open
Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial isozyme in the PDK family (PDK1-4) partially responsible for phosphorylation of pyruvate dehydrogenase (PDH). Phosphorylation of PDH is thought to result in a pro-proliferative shif…
View article: Role of <scp>MIF1</scp> / <scp>MIF2</scp> / <scp>CD74</scp> interactions in bladder cancer
Role of <span>MIF1</span> / <span>MIF2</span> / <span>CD74</span> interactions in bladder cancer Open
Macrophage migration inhibitory factor (MIF1) is a pleiotropic cytokine involved in inflammation and cancer. Genetic knockout of Mif1 in the validated N ‐butyl‐ N ‐(4‐hydroxybutyl) nitrosamine (BBN) model of bladder cancer (BCa) resulted i…
View article: USCAP 2022 Abstracts: Genitourinary Pathology (including renal tumors) (522-659)
USCAP 2022 Abstracts: Genitourinary Pathology (including renal tumors) (522-659) Open
Background: Clear cell adenocarcinoma (CCA) of the lower urinary tract is a rare generally aggressive adenocarcinoma that arises in the bladder or urethra, more commonly in women.Here in, we report the immunomorphologic features and clinic…
View article: USCAP 2022 Abstracts: Liver Pathology (1018-1075)
USCAP 2022 Abstracts: Liver Pathology (1018-1075) Open
Background: Men and post-menopausal women are at increased risk of developing non-alcoholic steatohepatitis (NASH) compared to pre-menopausal women.However, the impact of age and gender on NASH progression remains controversial.We sought t…