Katja Graumann
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View article: Biom3d, a modular framework to host and develop 3D segmentation methods
Biom3d, a modular framework to host and develop 3D segmentation methods Open
U-Net is a convolutional neural network model developed in 2015 and has proven to be one of the most inspiring deep-learning models for image segmentation. Numerous U-Net-based applications have since emerged, constituting a heterogeneous …
View article: In Depth Topological Analysis of Arabidopsis Mid-SUN Proteins and Their Interaction with the Membrane-Bound Transcription Factor MaMYB
In Depth Topological Analysis of Arabidopsis Mid-SUN Proteins and Their Interaction with the Membrane-Bound Transcription Factor MaMYB Open
Mid-SUN proteins are a neglected family of conserved type III membrane proteins of ancient origin with representatives in plants, animals, and fungi. Previous higher plant studies have associated them with functions at the nuclear envelope…
View article: Editorial: Understanding the key border: Structure, function, and dynamics of the plant nuclear envelope
Editorial: Understanding the key border: Structure, function, and dynamics of the plant nuclear envelope Open
EDITORIAL article Front. Plant Sci., 03 August 2022Sec. Plant Cell Biology https://doi.org/10.3389/fpls.2022.998823
View article: Deep learning – promises for 3D nuclear imaging: a guide for biologists
Deep learning – promises for 3D nuclear imaging: a guide for biologists Open
For the past century, the nucleus has been the focus of extensive investigations in cell biology. However, many questions remain about how its shape and size are regulated during development, in different tissues, or during disease and agi…
View article: Deep learning for nuclear image analysis and application to 3D plant nuclei
Deep learning for nuclear image analysis and application to 3D plant nuclei Open
International audience
View article: Finding the missing piece of the puzzle: how NMCPs fit into the plant nuclear lamina
Finding the missing piece of the puzzle: how NMCPs fit into the plant nuclear lamina Open
This article comments on: Masuda K, Hikida R, Fujino K. 2021. The plant nuclear lamina proteins NMCP1 and NMCP2 form a filamentous network with lateral filament associations. Journal of Experimental Botany 72, 6190–6204.
View article: Maize (Zea mays L.) Nucleoskeletal Proteins Regulate Nuclear Envelope Remodeling and Function in Stomatal Complex Development and Pollen Viability
Maize (Zea mays L.) Nucleoskeletal Proteins Regulate Nuclear Envelope Remodeling and Function in Stomatal Complex Development and Pollen Viability Open
In eukaryotes, the nuclear envelope (NE) encloses chromatin and separates it from the rest of the cell. The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex physically bridges across the NE, linking nuclear and cytoplasmic componen…
View article: Maize (<i>Zea mays L</i>.) nucleoskeletal proteins regulate nuclear envelope remodeling and function in stomatal complex development and pollen viability
Maize (<i>Zea mays L</i>.) nucleoskeletal proteins regulate nuclear envelope remodeling and function in stomatal complex development and pollen viability Open
In eukaryotes, the nuclear envelope (NE) encloses chromatin and separates it from the rest of the cell. The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex physically bridges across the NE, linking nuclear and cytoplasmic componen…
View article: MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation
MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation Open
The linker of nucleoskeleton and cytoskeleton (LINC) complex is an essential multi-protein structure spanning the eukaryotic nuclear envelope. The LINC complex functions to maintain nuclear architecture, positioning, and mobility, along wi…
View article: A nuclear localization signal targets tail-anchored membrane proteins to the inner nuclear envelope in plants
A nuclear localization signal targets tail-anchored membrane proteins to the inner nuclear envelope in plants Open
Protein targeting to the inner nuclear membrane (INM) is one of the least understood protein targeting pathways. INM proteins are important for chromatin organization, nuclear morphology and movement, and meiosis, and have been implicated …
View article: MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation
MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation Open
The linker of nucleoskeleton and cytoskeleton (LINC) complex is an essential multi-protein structure spanning the eukaryotic nuclear envelope. The LINC complex functions to maintain nuclear architecture, positioning, and mobility, along wi…
View article: Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions
Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions Open
The eukaryotic cell nucleus is a central organelle whose architecture determines genome function at multiple levels. Deciphering nuclear organizing principles influencing cellular responses and identity is a timely challenge. Despite many …
View article: MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation
MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation Open
The linker of nucleoskeleton and cytoskeleton (LINC) complex is an essential multi-protein structure spanning the eukaryotic nuclear envelope. The LINC complex functions to maintain nuclear architecture, positioning, and mobility, along wi…
View article: Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions
Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions Open
The eukaryotic cell nucleus is a central organelle whose architecture determines genome function at multiple levels. Deciphering nuclear organizing principles influencing cellular responses and identity is a timely challenge. Despite many …
View article: The nuclear envelope in higher plant mitosis and meiosis
The nuclear envelope in higher plant mitosis and meiosis Open
Mitosis and meiosis in higher plants involve significant reconfiguration of the nuclear envelope and the proteins that interact with it. The dynamic series of events involves a range of interactions, movement, breakdown, and reformation of…
View article: MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation
MLKS2 is an ARM domain and F-actin-associated KASH protein that functions in stomatal complex development and meiotic chromosome segregation Open
The linker of nucleoskeleton and cytoskeleton (LINC) complex is an essential multi-protein structure spanning the eukaryotic nuclear envelope. The LINC complex functions to maintain nuclear architecture, positioning, and mobility, along wi…
View article: Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions
Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions Open
The eukaryotic cell nucleus is a central organelle whose architecture determines genome function at multiple levels. Deciphering nuclear organizing principles influencing cellular responses and identity is a timely challenge. Despite many …
View article: Identifying essential components of a plant LINC complex
Identifying essential components of a plant LINC complex Open
The higher plant NE contains a functional Linker of Nucleoskeleton and Cytoskeleton (LINC) complex based on conserved Sad1-Unc84 (SUN) domain proteins and plant specific Klarsicht/Anc1/Syne homology (KASH) domain proteins (Figure 1). Recen…
View article: The cell wall of Arabidopsis thaliana influences actin network dynamics
The cell wall of Arabidopsis thaliana influences actin network dynamics Open
In plant cells, molecular connections link the cell wall-plasma membrane-actin cytoskeleton to form a continuum. It is hypothesized that the cell wall provides stable anchor points around which the actin cytoskeleton remodels. Here we use …
View article: Nuclear Envelope Associated Tether (NEAT) system
Nuclear Envelope Associated Tether (NEAT) system Open
Creating transgenic plants relies on the random insertion of genes into DNA. Insert position within the genome can play a huge role in the expression level of the transgene. In other model systems, studies have shown that the physical posi…
View article: Exploring the evolution of the proteins of the plant nuclear envelope
Exploring the evolution of the proteins of the plant nuclear envelope Open
In this study, we explore the plasticity during evolution of proteins of the higher plant nuclear envelope (NE) from the most ancestral plant species to advanced angiosperms. The higher plant NE contains a functional Linker of Nucleoskelet…
View article: A novel family of plant nuclear envelope-associated proteins
A novel family of plant nuclear envelope-associated proteins Open
This paper describes the characterisation of a new family of higher plant nuclear envelope-associated proteins (NEAPs) that interact with other proteins of the nuclear envelope. In the model plant Arabidopsis thaliana, the family consists …
View article: Marker gene tethering by nucleoporins affects gene expression in plants
Marker gene tethering by nucleoporins affects gene expression in plants Open
In non-plant systems, chromatin association with the nuclear periphery affects gene expression, where interactions with nuclear envelope proteins can repress and interactions with nucleoporins can enhance transcription. In plants, both het…
View article: The plant nuclear envelope as a multifunctional platform LINCed by SUN and KASH
The plant nuclear envelope as a multifunctional platform LINCed by SUN and KASH Open
The nuclear envelope (NE) is a double membrane system enclosing the genome of eukaryotes. Besides nuclear pore proteins, which form channels at the NE, nuclear membranes are populated by a collection of NE proteins that perform various cel…