Katja Steinhorst
YOU?
Author Swipe
View article: Learning in the Single-Cell Organism Physarum polycephalum: Effect of Propofol
Learning in the Single-Cell Organism Physarum polycephalum: Effect of Propofol Open
Propofol belongs to a class of molecules that are known to block learning and memory in mammals, including rodents and humans. Interestingly, learning and memory are not tied to the presence of a nervous system. There are several lines of …
View article: Repurposing of the antibiotic nitroxoline for the treatment of mpox
Repurposing of the antibiotic nitroxoline for the treatment of mpox Open
The antiviral drugs tecovirimat, brincidofovir, and cidofovir are considered for mpox (monkeypox) treatment despite a lack of clinical evidence. Moreover, their use is affected by toxic side‐effects (brincidofovir, cidofovir), limited avai…
View article: Repurposing of the antibiotic nitroxoline for the treatment of mpox
Repurposing of the antibiotic nitroxoline for the treatment of mpox Open
The antiviral drugs tecovirimat, brincidofovir, and cidofovir are considered for mpox (monkeypox) treatment despite a lack of clinical evidence. Moreover, their use is affected by toxic side-effects (brincidofovir, cidofovir), limited avai…
View article: Drug Sensitivity of Currently Circulating Mpox Viruses
Drug Sensitivity of Currently Circulating Mpox Viruses Open
suggest an increased incidence of ectopic pregnancy detected after abortion with the use of no-touch protocols. 5However, clinicians must maintain a high index of suspicion for ectopic pregnancy in persons presenting with suggestive sympto…
View article: Functional Downregulation of PD-L1 and PD-L2 by CpG and non-CpG Oligonucleotides in Melanoma Cells
Functional Downregulation of PD-L1 and PD-L2 by CpG and non-CpG Oligonucleotides in Melanoma Cells Open
The clinical application of immune checkpoint inhibitors represents a breakthrough progress in the treatment of metastasized melanoma and other tumor entities. In the present study, it was hypothesized that oligonucleotides (ODNs), known a…
View article: G protein‐coupled receptor 40 expression in human melanoma – correlation with tumour thickness, <scp>AJCC</scp> stage and survival
G protein‐coupled receptor 40 expression in human melanoma – correlation with tumour thickness, <span>AJCC</span> stage and survival Open
Background In melanoma, preclinical data suggest a possible role of polyunsaturated fatty acids inhibiting cell growth. A new target molecule for free fatty acids, the G protein‐coupled receptor GPR 40, was identified in melanoma cells. Ob…
View article: Collagen I Promotes Adipocytogenesis in Adipose-Derived Stem Cells In Vitro
Collagen I Promotes Adipocytogenesis in Adipose-Derived Stem Cells In Vitro Open
A hallmark of ageing is the redistribution of body fat. Particularly, subcutaneous fat decreases paralleled by a decrease of skin collagen I are typical for age-related skin atrophy. In this paper, we hypothesize that collagen I may be a r…
View article: Sensitization of human melanoma cells for TRAIL-induced apoptosis by a selective aurora kinase A inhibitor
Sensitization of human melanoma cells for TRAIL-induced apoptosis by a selective aurora kinase A inhibitor Open
Different therapeutic strategies in metastatic melanoma focused on signalling pathways controlling cell proliferation, cell cycle and apoptosis. While TRAIL (TNF-related apoptosis inducing ligand) has been shown to be an interesting candid…