Katrina Schmidt
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View article: Characterization of the Structural Requirements for the NADase Activity of Bacterial Toll/IL-1R domains in a Course-based Undergraduate Research Experience
Characterization of the Structural Requirements for the NADase Activity of Bacterial Toll/IL-1R domains in a Course-based Undergraduate Research Experience Open
TLRs initiate innate immune signaling pathways via Toll/IL-1R (TIR) domains on their cytoplasmic tails. Various bacterial species also express TIR domain-containing proteins that contribute to bacterial evasion of the innate immune system.…
View article: The structure of NAD<sup>+</sup>consuming protein<i>Acinetobacter baumannii</i>TIR domain shows unique kinetics and conformations
The structure of NAD<sup>+</sup>consuming protein<i>Acinetobacter baumannii</i>TIR domain shows unique kinetics and conformations Open
Toll-like and Interleukin-1/18 receptor resistance (TIR) domain-containing proteins function as important signaling and immune regulatory molecules. TIR domain-containing proteins identified in eukaryotic and prokaryotic species also exhib…