Kausik Regunath
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View article: Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway–dependent Rho/ROCK signaling
Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway–dependent Rho/ROCK signaling Open
Certain TP53 mutations can confer neomorphic gain of function (GOF) activities to the p53 protein that affect cancer progression. Yet the concept of mutant p53 GOF has been challenged. Here, using various strategies to alter the status of …
View article: Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling
Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling Open
Certain mutations can confer neomorphic gain of function (GOF) activities to the p53 protein that affect cancer progression. Yet the concept of mutant p53 GOF has been challenged. Here, using various strategies to alter the status of mutan…
View article: Supplementary Table S3 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S3 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S3 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in glioblastoma.
View article: Supplementary Figure S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S5 shows Kaplan Meier curves from TCGA cancer datasets
View article: List of Supplementary Tables from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
List of Supplementary Tables from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
List of Supplementary Tables with description of each table in the manuscript
View article: Supplementary Table S4 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S4 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S4 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in prostate cancers.
View article: Supplementary Table S8 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S8 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S8 shows publicly available ChIP-seq datasets pertaining to p53
View article: Supplementary Table S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S1 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in breast cancers.
View article: Supplementary Figure S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S6 shows amplified and deleted lncRNAs from TCGA cancer datasets that are correlated with better or worse survival
View article: List of Supplementary Tables from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
List of Supplementary Tables from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
List of Supplementary Tables with description of each table in the manuscript
View article: Supplementary Table S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S5 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in pancreatic cancers.
View article: Supplementary Figure Legends from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure Legends from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Legends for all Supplementary Figures in the manuscript
View article: Supplementary Figure S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S5 shows Kaplan Meier curves from TCGA cancer datasets
View article: Supplementary Table S2 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S2 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S2 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in colon cancers.
View article: Supplementary Figure Legends from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure Legends from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Legends for all Supplementary Figures in the manuscript
View article: Supplementary Table S8 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S8 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S8 shows publicly available ChIP-seq datasets pertaining to p53
View article: Supplementary Table S4 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S4 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S4 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in prostate cancers.
View article: Data from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Data from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
The p53 tumor suppressor protein, a sequence-specific DNA binding transcription factor, regulates the expression of a large number of genes, in response to various forms of cellular stress. Although the protein coding target genes of p53 h…
View article: Supplementary Table S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S1 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in breast cancers.
View article: Supplementary Figure S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S1 shows cell cycle profiles, volcano plots, heatmap and quantification of p53 levels from HCT116 cells treated with control or drugs
View article: Supplementary Figure S4 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S4 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S4 shows heatmap of p53LTCC expression in breast cancer samples comparing tumors with wild-type p53 vs mutant p53
View article: Supplementary Figure S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S1 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S1 shows cell cycle profiles, volcano plots, heatmap and quantification of p53 levels from HCT116 cells treated with control or drugs
View article: Supplementary Figure S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S6 shows amplified and deleted lncRNAs from TCGA cancer datasets that are correlated with better or worse survival
View article: Supplementary Table S7 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S7 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S7 shows p53LTCC LncRNAs deleted in five different cancers
View article: Supplementary Figure S3 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S3 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S3 shows heatmap of p53LTCC expression in breast, colon and prostate cancers
View article: Supplementary Table S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S6 shows p53LTCC LncRNAs differentially expressed in three cancers (comparing samples with wild-type vs mutant p53)
View article: Supplementary Table S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S6 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S6 shows p53LTCC LncRNAs differentially expressed in three cancers (comparing samples with wild-type vs mutant p53)
View article: Supplementary Table S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S5 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S5 shows p53LTCC lncRNAs (activated and repressed) associated with patient survival in pancreatic cancers.
View article: Supplementary Table S7 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Table S7 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Table S7 shows p53LTCC LncRNAs deleted in five different cancers
View article: Supplementary Figure S3 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types
Supplementary Figure S3 from Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types Open
Supplementary Figure S3 shows heatmap of p53LTCC expression in breast, colon and prostate cancers